Tags

Type your tag names separated by a space and hit enter

Evaluation of antifungal activity of six children's toothpaste on Candida albicans isolated from early childhood caries patients.
J Indian Soc Pedod Prev Dent. 2020 Apr-Jun; 38(2):152-157.JI

Abstract

Background

Early childhood caries (ECC) is an aggressive, destructive form of dental caries that affects the children younger than 6 years of age. Candida is known to increase the adherence of Streptococcus mutans to the oral biofilm and produce acids that cause tooth demineralization.

Aim of the Study

To evaluate the efficacy of six commercially available children's toothpaste on clinical isolates of Candida albicans obtained from ECC patients.

Materials and Methods

The study population comprised 60 children aged 3-6 years having ECC. Samples were divided into six groups comprising ten children in each group. Samples were collected using sterile cotton swabs, inoculated on Sabouraud dextrose agar, and incubated at 37°C for 24 h. Species identification was done by germ tube test and growth on corn meal agar. After the confirmed growth of C. albicans, the six commercially available children's toothpaste namely Organic Children's Coconut Oil Toothpaste®, Aloe Dent Children's Toothpaste®, Patanjali Dant Kanti Junior Toothpaste®, Colgate Kids Toothpaste®, Pediflor Kids Toothpaste®, and Crest Pro-Health Stages Kids Toothpaste® and distilled water as control group were subjected for antifungal activity of C. albicans. Agar plates were incubated at 37°C for 48 h, and the diameter of the zones of inhibition was measured and recorded. Data were tabulated and statistical analysis was done using Statistical Package for the Social Science (16.0) version.

Results

Pediflor kids toothpaste® showed maximum antifungal activity and Aloe Dent children's toothpaste® showed minimum antifungal activity.

Conclusion

All brands of children's toothpaste show antifungal activity against Candida albicans.

Authors+Show Affiliations

Department of Pediatric and Preventive Dentistry, Kannur Dental College, Kannur, Kerala, India.Department of Pediatric and Preventive Dentistry, Kannur Dental College, Kannur, Kerala, India.Department of Pediatric and Preventive Dentistry, Kannur Dental College, Kannur, Kerala, India.Department of Microbiology, Kannur Medical College, Kannur, Kerala, India.Department of Pediatric and Preventive Dentistry, Kannur Dental College, Kannur, Kerala, India.Department of Pediatric and Preventive Dentistry, Kannur Dental College, Kannur, Kerala, India.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32611861

Citation

Chandhru, T P., et al. "Evaluation of Antifungal Activity of Six Children's Toothpaste On Candida Albicans Isolated From Early Childhood Caries Patients." Journal of the Indian Society of Pedodontics and Preventive Dentistry, vol. 38, no. 2, 2020, pp. 152-157.
Chandhru TP, Anusha VR, Peedikayil FC, et al. Evaluation of antifungal activity of six children's toothpaste on Candida albicans isolated from early childhood caries patients. J Indian Soc Pedod Prev Dent. 2020;38(2):152-157.
Chandhru, T. P., Anusha, V. R., Peedikayil, F. C., Gufran Ahmed, M. B., Kottayi, S., & Narasimhan, D. (2020). Evaluation of antifungal activity of six children's toothpaste on Candida albicans isolated from early childhood caries patients. Journal of the Indian Society of Pedodontics and Preventive Dentistry, 38(2), 152-157. https://doi.org/10.4103/JISPPD.JISPPD_3_20
Chandhru TP, et al. Evaluation of Antifungal Activity of Six Children's Toothpaste On Candida Albicans Isolated From Early Childhood Caries Patients. J Indian Soc Pedod Prev Dent. 2020 Apr-Jun;38(2):152-157. PubMed PMID: 32611861.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Evaluation of antifungal activity of six children's toothpaste on Candida albicans isolated from early childhood caries patients. AU - Chandhru,T P, AU - Anusha,V R, AU - Peedikayil,Faizal C, AU - Gufran Ahmed,M B, AU - Kottayi,Soni, AU - Narasimhan,Dhanesh, PY - 2020/7/3/entrez PY - 2020/7/3/pubmed PY - 2020/7/4/medline KW - Candida albicans KW - early childhood caries KW - toothpaste SP - 152 EP - 157 JF - Journal of the Indian Society of Pedodontics and Preventive Dentistry JO - J Indian Soc Pedod Prev Dent VL - 38 IS - 2 N2 - Background: Early childhood caries (ECC) is an aggressive, destructive form of dental caries that affects the children younger than 6 years of age. Candida is known to increase the adherence of Streptococcus mutans to the oral biofilm and produce acids that cause tooth demineralization. Aim of the Study: To evaluate the efficacy of six commercially available children's toothpaste on clinical isolates of Candida albicans obtained from ECC patients. Materials and Methods: The study population comprised 60 children aged 3-6 years having ECC. Samples were divided into six groups comprising ten children in each group. Samples were collected using sterile cotton swabs, inoculated on Sabouraud dextrose agar, and incubated at 37°C for 24 h. Species identification was done by germ tube test and growth on corn meal agar. After the confirmed growth of C. albicans, the six commercially available children's toothpaste namely Organic Children's Coconut Oil Toothpaste®, Aloe Dent Children's Toothpaste®, Patanjali Dant Kanti Junior Toothpaste®, Colgate Kids Toothpaste®, Pediflor Kids Toothpaste®, and Crest Pro-Health Stages Kids Toothpaste® and distilled water as control group were subjected for antifungal activity of C. albicans. Agar plates were incubated at 37°C for 48 h, and the diameter of the zones of inhibition was measured and recorded. Data were tabulated and statistical analysis was done using Statistical Package for the Social Science (16.0) version. Results: Pediflor kids toothpaste® showed maximum antifungal activity and Aloe Dent children's toothpaste® showed minimum antifungal activity. Conclusion: All brands of children's toothpaste show antifungal activity against Candida albicans. SN - 1998-3905 UR - https://www.unboundmedicine.com/medline/citation/32611861/Evaluation_of_antifungal_activity_of_six_children's_toothpaste_on_Candida_albicans_isolated_from_early_childhood_caries_patients DB - PRIME DP - Unbound Medicine ER -