Tags

Type your tag names separated by a space and hit enter

Comparative evaluation of a novel herbal anesthetic gel and 2% lignocaine gel as an intraoral topical anesthetic agent in children: Bilateral split-mouth, single-blind, crossover in vivo study.
J Indian Soc Pedod Prev Dent. 2020 Apr-Jun; 38(2):177-183.JI

Abstract

Background

Topical anesthetics have an intrinsic part to reduce pricking pain sensation due to needle stick before injection in children.

Aim

The present study aimed to determine the effectiveness of a novel herbal anesthetic gel used as a topical anesthetic before an inferior alveolar nerve block.

SettingsandDesign

This was a bilateral split-mouth, single blind, crossoverin vivo study.

Methods

Atotal number of 30 children were selected for this study design. After the application of the topical anesthesia, a 26-gauge needle was inserted in the mucobuccal fold and local anesthetic solution was deposited. Assessment of pain perception was done before the procedure and at the time of needle penetration using hemodynamic parameters such as blood pressure and heart rate. The objective and subjective pain assessment was recoded through sound eye motor scale and Faces Pain Scale-Revised (FPS-R).

StatisticalAnalysis

As the data followed a normal distribution, parametric tests were used to analyze these data. The independent sample t-test and paired sample t-test were used to check the mean differences.

Results

The data showed no statistically significant differences in the objective and subjective pain assessment values of the novel herbal anesthetic gel compared to the 2% lignocaine gel. However, the intragroup comparisons of the before and during treatment results showed statistically significant results (P < 0.05).

Conclusion

The novel herbal anesthetic gel was effective and safe in reducing the pain from needle insertion. Thus, setting up scientific evidence for the therapeutic usage of herbal products can, therefore, assist to develop a more efficient and alternative topical anesthetic.

Authors+Show Affiliations

Department of Pediatric and Preventive Dentistry, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Medical Sciences (Deemed to be University), Wardha, Maharashtra, India.Department of Pediatric and Preventive Dentistry, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Medical Sciences (Deemed to be University), Wardha, Maharashtra, India.Department of Pediatric and Preventive Dentistry, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Medical Sciences (Deemed to be University), Wardha, Maharashtra, India.Department of Pediatric and Preventive Dentistry, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Medical Sciences (Deemed to be University), Wardha, Maharashtra, India.Department of Pharmacology and Materia Medica, Datta Meghe Institute of Ayurvedic Medical College, Hospital and Research Centre, Nagpur, Maharashtra, India.Department of Pediatric and Preventive Dentistry, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Medical Sciences (Deemed to be University), Wardha, Maharashtra, India.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32611865

Citation

Mohite, Vedangi Arvind, et al. "Comparative Evaluation of a Novel Herbal Anesthetic Gel and 2% Lignocaine Gel as an Intraoral Topical Anesthetic Agent in Children: Bilateral Split-mouth, Single-blind, Crossover in Vivo Study." Journal of the Indian Society of Pedodontics and Preventive Dentistry, vol. 38, no. 2, 2020, pp. 177-183.
Mohite VA, Baliga S, Thosar N, et al. Comparative evaluation of a novel herbal anesthetic gel and 2% lignocaine gel as an intraoral topical anesthetic agent in children: Bilateral split-mouth, single-blind, crossover in vivo study. J Indian Soc Pedod Prev Dent. 2020;38(2):177-183.
Mohite, V. A., Baliga, S., Thosar, N., Rathi, N., Khobragade, P., & Srivastava, R. (2020). Comparative evaluation of a novel herbal anesthetic gel and 2% lignocaine gel as an intraoral topical anesthetic agent in children: Bilateral split-mouth, single-blind, crossover in vivo study. Journal of the Indian Society of Pedodontics and Preventive Dentistry, 38(2), 177-183. https://doi.org/10.4103/JISPPD.JISPPD_226_20
Mohite VA, et al. Comparative Evaluation of a Novel Herbal Anesthetic Gel and 2% Lignocaine Gel as an Intraoral Topical Anesthetic Agent in Children: Bilateral Split-mouth, Single-blind, Crossover in Vivo Study. J Indian Soc Pedod Prev Dent. 2020 Apr-Jun;38(2):177-183. PubMed PMID: 32611865.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparative evaluation of a novel herbal anesthetic gel and 2% lignocaine gel as an intraoral topical anesthetic agent in children: Bilateral split-mouth, single-blind, crossover in vivo study. AU - Mohite,Vedangi Arvind, AU - Baliga,Sudhindra, AU - Thosar,Nilima, AU - Rathi,Nilesh, AU - Khobragade,Pramod, AU - Srivastava,Rashi, PY - 2020/7/3/entrez PY - 2020/7/3/pubmed PY - 2020/7/4/medline KW - KW - 2% lignocaine gel KW - faces pain scale-revised scale KW - sound eye motor scale KW - topical anesthetic gel SP - 177 EP - 183 JF - Journal of the Indian Society of Pedodontics and Preventive Dentistry JO - J Indian Soc Pedod Prev Dent VL - 38 IS - 2 N2 - Background: Topical anesthetics have an intrinsic part to reduce pricking pain sensation due to needle stick before injection in children. Aim: The present study aimed to determine the effectiveness of a novel herbal anesthetic gel used as a topical anesthetic before an inferior alveolar nerve block. SettingsandDesign: This was a bilateral split-mouth, single blind, crossoverin vivo study. Methods: Atotal number of 30 children were selected for this study design. After the application of the topical anesthesia, a 26-gauge needle was inserted in the mucobuccal fold and local anesthetic solution was deposited. Assessment of pain perception was done before the procedure and at the time of needle penetration using hemodynamic parameters such as blood pressure and heart rate. The objective and subjective pain assessment was recoded through sound eye motor scale and Faces Pain Scale-Revised (FPS-R). StatisticalAnalysis: As the data followed a normal distribution, parametric tests were used to analyze these data. The independent sample t-test and paired sample t-test were used to check the mean differences. Results: The data showed no statistically significant differences in the objective and subjective pain assessment values of the novel herbal anesthetic gel compared to the 2% lignocaine gel. However, the intragroup comparisons of the before and during treatment results showed statistically significant results (P < 0.05). Conclusion: The novel herbal anesthetic gel was effective and safe in reducing the pain from needle insertion. Thus, setting up scientific evidence for the therapeutic usage of herbal products can, therefore, assist to develop a more efficient and alternative topical anesthetic. SN - 1998-3905 UR - https://www.unboundmedicine.com/medline/citation/32611865/Comparative_evaluation_of_a_novel_herbal_anesthetic_gel_and_2%_lignocaine_gel_as_an_intraoral_topical_anesthetic_agent_in_children:_Bilateral_split-mouth,_single-blind,_crossover_in_vivo_study DB - PRIME DP - Unbound Medicine ER -