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Appendiceal Diverticular Disease: A 10-year Retrospective Study of Cases from Tertiary Hospitals in Western Australia.
Chirurgia (Bucur). 2020 May-Jun; 115(3):348-356.C

Abstract

Background:

Appendiceal diverticular disease (ADD) is typically a histological diagnosis. Our paper aims to investigate the implications of ADD compared to acute appendicitis (AA).

Methods:

We conducted a retrospective data collection of patients who had undergone an appen dicectomy in three tertiary hospitals across Western Australia between 2009-2019 and included patients with histopathological diagnoses of ADD and AA.

Results:

Thirty-seven patients with ADD and forty with AA were included. The mean age in the ADD group was significantly older (p 0.001) at 50.1 compared to the AA group (37.3). The mean white cell count (WCC) in the ADD group was lower than the AA group (11x109/L vs. 13.3x109/L, p 0.001), whereas the C-Reactive Protein (CRP) level was greater, although not statistically significant. The ADD group had a greater risk of major surgery (p 0.05) and complications such as appendiceal perforation and appendiceal mass (p 0.05). Post-operative colonoscopy also demon strated a higher incidence of polyps in patients with ADD (19% vs. 2.5%, p 0.001).

Conclusion:

ADD frequently presents with clinical features indiscernible from AA. Our study demonstrates that ADD is associated with higher rates of appendiceal perforation, polyps and malignancy. We recommend that patients with ADD be advised to have a colonoscopy post-opera tively to rule out underlying malignancy.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32614290

Citation

Toh, Pei Yinn, et al. "Appendiceal Diverticular Disease: a 10-year Retrospective Study of Cases From Tertiary Hospitals in Western Australia." Chirurgia (Bucharest, Romania : 1990), vol. 115, no. 3, 2020, pp. 348-356.
Toh PY, Parys S, Watanabe Y. Appendiceal Diverticular Disease: A 10-year Retrospective Study of Cases from Tertiary Hospitals in Western Australia. Chirurgia (Bucur). 2020;115(3):348-356.
Toh, P. Y., Parys, S., & Watanabe, Y. (2020). Appendiceal Diverticular Disease: A 10-year Retrospective Study of Cases from Tertiary Hospitals in Western Australia. Chirurgia (Bucharest, Romania : 1990), 115(3), 348-356. https://doi.org/10.21614/chirurgia.115.3.348
Toh PY, Parys S, Watanabe Y. Appendiceal Diverticular Disease: a 10-year Retrospective Study of Cases From Tertiary Hospitals in Western Australia. Chirurgia (Bucur). 2020 May-Jun;115(3):348-356. PubMed PMID: 32614290.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Appendiceal Diverticular Disease: A 10-year Retrospective Study of Cases from Tertiary Hospitals in Western Australia. AU - Toh,Pei Yinn, AU - Parys,Simon, AU - Watanabe,Yuki, PY - 2020/06/01/accepted PY - 2020/7/3/entrez PY - 2020/7/3/pubmed PY - 2020/7/8/medline KW - acuteappendicitis KW - appendicealdiverticulum KW - diverticulitis SP - 348 EP - 356 JF - Chirurgia (Bucharest, Romania : 1990) JO - Chirurgia (Bucur) VL - 115 IS - 3 N2 - Background: Appendiceal diverticular disease (ADD) is typically a histological diagnosis. Our paper aims to investigate the implications of ADD compared to acute appendicitis (AA). Methods: We conducted a retrospective data collection of patients who had undergone an appen dicectomy in three tertiary hospitals across Western Australia between 2009-2019 and included patients with histopathological diagnoses of ADD and AA. Results: Thirty-seven patients with ADD and forty with AA were included. The mean age in the ADD group was significantly older (p 0.001) at 50.1 compared to the AA group (37.3). The mean white cell count (WCC) in the ADD group was lower than the AA group (11x109/L vs. 13.3x109/L, p 0.001), whereas the C-Reactive Protein (CRP) level was greater, although not statistically significant. The ADD group had a greater risk of major surgery (p 0.05) and complications such as appendiceal perforation and appendiceal mass (p 0.05). Post-operative colonoscopy also demon strated a higher incidence of polyps in patients with ADD (19% vs. 2.5%, p 0.001). Conclusion: ADD frequently presents with clinical features indiscernible from AA. Our study demonstrates that ADD is associated with higher rates of appendiceal perforation, polyps and malignancy. We recommend that patients with ADD be advised to have a colonoscopy post-opera tively to rule out underlying malignancy. SN - 1221-9118 UR - https://www.unboundmedicine.com/medline/citation/32614290/Appendiceal_Diverticular_Disease:_A_10-year_Retrospective_Study_of_Cases_from_Tertiary_Hospitals_in_Western_Australia L2 - http://www.diseaseinfosearch.org/result/2310 DB - PRIME DP - Unbound Medicine ER -