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Atypical MOG antibody disease presenting with typical multiple sclerosis lesions.
Mult Scler Relat Disord. 2020 Jun 26; 44:102342.MS

Abstract

Myelin oligodendrocyte glycoprotein (MOG) antibody disease is an autoimmune disease of the central nervous system associated with a serological antibody against MOG, a glycoprotein expressed on the outer membrane of myelin. It is solely found within the central nervous system in the brain, optic nerves and spinal cord. MOG antibody disease falls within the neuromyelitis optica spectrum disorders (NMOSD), however clinical characteristics appear distinct from aquaporin-4 antibody related disease and multiple sclerosis. It has predilection for causing recurrent optic neuritis and transverse myelitis. Accurate diagnosis is important to determine long term prognosis and suitable treatment. We describe the case of a 42 year old woman previously labelled as MS who demonstrated a variable presentation of MOG antibody disease.

Authors+Show Affiliations

Department of Neurology, University of Kentucky, Lexington, Kentucky, USA. Electronic address: katelyn.dolbec@gmail.com.Department of Neurology, University of Kentucky, Lexington, Kentucky, USA.Department of Neurology, University of Kentucky, Lexington, Kentucky, USA. Electronic address: padmaja.sudhakar@uky.edu.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32615531

Citation

Dolbec, Katelyn, et al. "Atypical MOG Antibody Disease Presenting With Typical Multiple Sclerosis Lesions." Multiple Sclerosis and Related Disorders, vol. 44, 2020, p. 102342.
Dolbec K, Chalkley J, Sudhakar P. Atypical MOG antibody disease presenting with typical multiple sclerosis lesions. Mult Scler Relat Disord. 2020;44:102342.
Dolbec, K., Chalkley, J., & Sudhakar, P. (2020). Atypical MOG antibody disease presenting with typical multiple sclerosis lesions. Multiple Sclerosis and Related Disorders, 44, 102342. https://doi.org/10.1016/j.msard.2020.102342
Dolbec K, Chalkley J, Sudhakar P. Atypical MOG Antibody Disease Presenting With Typical Multiple Sclerosis Lesions. Mult Scler Relat Disord. 2020 Jun 26;44:102342. PubMed PMID: 32615531.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Atypical MOG antibody disease presenting with typical multiple sclerosis lesions. AU - Dolbec,Katelyn, AU - Chalkley,Joshua, AU - Sudhakar,Padmaja, Y1 - 2020/06/26/ PY - 2020/05/27/received PY - 2020/06/25/revised PY - 2020/06/25/accepted PY - 2020/7/3/pubmed PY - 2020/7/3/medline PY - 2020/7/3/entrez SP - 102342 EP - 102342 JF - Multiple sclerosis and related disorders JO - Mult Scler Relat Disord VL - 44 N2 - Myelin oligodendrocyte glycoprotein (MOG) antibody disease is an autoimmune disease of the central nervous system associated with a serological antibody against MOG, a glycoprotein expressed on the outer membrane of myelin. It is solely found within the central nervous system in the brain, optic nerves and spinal cord. MOG antibody disease falls within the neuromyelitis optica spectrum disorders (NMOSD), however clinical characteristics appear distinct from aquaporin-4 antibody related disease and multiple sclerosis. It has predilection for causing recurrent optic neuritis and transverse myelitis. Accurate diagnosis is important to determine long term prognosis and suitable treatment. We describe the case of a 42 year old woman previously labelled as MS who demonstrated a variable presentation of MOG antibody disease. SN - 2211-0356 UR - https://www.unboundmedicine.com/medline/citation/32615531/Atypical_MOG_antibody_disease_presenting_with_typical_multiple_sclerosis_lesions L2 - https://linkinghub.elsevier.com/retrieve/pii/S2211-0348(20)30418-1 DB - PRIME DP - Unbound Medicine ER -
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