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[Non-inflammatory muscle pain].
Dtsch Med Wochenschr. 2020 Jul; 145(13):887-894.DM

Abstract

Muscle pain as a common symptom in daily practice frequently occurs as a non-specific accompanying symptom in multiple internal and neurological diseases. Primarily inflammatory or autoimmune muscular diseases are causing muscle pain. However, a number of non-inflammatory causes of pain can also be considered for differential diagnosis. These are presented in this article. In principle, a distinction must be made between focal and diffuse muscle pain. As an invasive diagnostic procedure, a muscle biopsy should only be performed as the last step in the diagnostic alogorithm. If diffuse muscle pain is only associated with slight muscle weakness or is completely absent, there is usually a primary rheumatic cause. Statins (HMG-CoA reductase inhibitors) can lead to rhabdomyolysis, muscle fiber atrophy and muscle necrosis by damaging the muscle fiber membrane. Myotonias are autosomal dominant or autosomal recessive inherited disorders of muscle function. The genetic defect leads to pronounced muscle stiffness. The cause of metabolic myopathies can be disorders of the carbohydrate, fat or purine metabolism. Fibromyalgia syndrome (FMS) is a non-inflammatory disease and, according to the current knowledge, recognized as the result of an exposure to physical, biological and psychosocial factors (biopsychological disease model). To help diagnosing FMS, pain regions and core symptoms (fatigue, sleep disturbances) can be detected using questionnaires (Widespread Pain Index [WPI] and Symptom Severity Scale [SSS]).

Authors

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Pub Type(s)

English Abstract
Journal Article

Language

ger

PubMed ID

32615603

Citation

Roicke, Hannes, et al. "[Non-inflammatory Muscle Pain]." Deutsche Medizinische Wochenschrift (1946), vol. 145, no. 13, 2020, pp. 887-894.
Roicke H, Köhler W, Baum P, et al. [Non-inflammatory muscle pain]. Dtsch Med Wochenschr. 2020;145(13):887-894.
Roicke, H., Köhler, W., Baum, P., Baerwald, C., & Krasselt, M. (2020). [Non-inflammatory muscle pain]. Deutsche Medizinische Wochenschrift (1946), 145(13), 887-894. https://doi.org/10.1055/a-1068-5210
Roicke H, et al. [Non-inflammatory Muscle Pain]. Dtsch Med Wochenschr. 2020;145(13):887-894. PubMed PMID: 32615603.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Non-inflammatory muscle pain]. AU - Roicke,Hannes, AU - Köhler,Wolfgang, AU - Baum,Petra, AU - Baerwald,Christoph, AU - Krasselt,Marco, Y1 - 2020/07/02/ PY - 2020/7/3/entrez PY - 2020/7/3/pubmed PY - 2020/7/3/medline SP - 887 EP - 894 JF - Deutsche medizinische Wochenschrift (1946) JO - Dtsch. Med. Wochenschr. VL - 145 IS - 13 N2 - Muscle pain as a common symptom in daily practice frequently occurs as a non-specific accompanying symptom in multiple internal and neurological diseases. Primarily inflammatory or autoimmune muscular diseases are causing muscle pain. However, a number of non-inflammatory causes of pain can also be considered for differential diagnosis. These are presented in this article. In principle, a distinction must be made between focal and diffuse muscle pain. As an invasive diagnostic procedure, a muscle biopsy should only be performed as the last step in the diagnostic alogorithm. If diffuse muscle pain is only associated with slight muscle weakness or is completely absent, there is usually a primary rheumatic cause. Statins (HMG-CoA reductase inhibitors) can lead to rhabdomyolysis, muscle fiber atrophy and muscle necrosis by damaging the muscle fiber membrane. Myotonias are autosomal dominant or autosomal recessive inherited disorders of muscle function. The genetic defect leads to pronounced muscle stiffness. The cause of metabolic myopathies can be disorders of the carbohydrate, fat or purine metabolism. Fibromyalgia syndrome (FMS) is a non-inflammatory disease and, according to the current knowledge, recognized as the result of an exposure to physical, biological and psychosocial factors (biopsychological disease model). To help diagnosing FMS, pain regions and core symptoms (fatigue, sleep disturbances) can be detected using questionnaires (Widespread Pain Index [WPI] and Symptom Severity Scale [SSS]). SN - 1439-4413 UR - https://www.unboundmedicine.com/medline/citation/32615603/[Non-inflammatory_muscle_pain] L2 - http://www.thieme-connect.com/DOI/DOI?10.1055/a-1068-5210 DB - PRIME DP - Unbound Medicine ER -
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