Tags

Type your tag names separated by a space and hit enter

Efficacy of experimental phage therapies in livestock.
Anim Health Res Rev. 2020 Jun 19 [Online ahead of print]AH

Abstract

Bacteriophages are the most abundant form of life on earth and are present everywhere. The total number of bacteriophages has been estimated to be 1032 virions. The main division of bacteriophages is based on the type of nucleic acid (DNA or RNA) and on the structure of the capsid. Due to the significant increase in the number of multi-drug-resistant bacteria, bacteriophages could be a useful tool as an alternative to antibiotics in experimental therapies to prevent and to control bacterial infections in people and animals. The aim of this review was to discuss the history of phage therapy as a replacement for antibiotics, in response to EU regulations prohibiting the use of antibiotics in livestock, and to present current examples and results of experimental phage treatments in comparison to antibiotics. The use of bacteriophages to control human infections has had a high success rate, especially in mixed infections caused mainly by Staphylococcus, Pseudomonas, Enterobacter, and Enterococcus. Bacteriophages have also proven to be an effective tool in experimental treatments for combating diseases in livestock.

Authors+Show Affiliations

Sub-Department of Veterinary Prevention and Avian Diseases, Institute of Biological Basis of Animal Diseases, Faculty of Veterinary Medicine, University of Life Sciences, Akademicka 12, 20-033 Lublin, Poland.Sub-Department of Veterinary Prevention and Avian Diseases, Institute of Biological Basis of Animal Diseases, Faculty of Veterinary Medicine, University of Life Sciences, Akademicka 12, 20-033 Lublin, Poland.Sub-Department of Veterinary Prevention and Avian Diseases, Institute of Biological Basis of Animal Diseases, Faculty of Veterinary Medicine, University of Life Sciences, Akademicka 12, 20-033 Lublin, Poland.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32618543

Citation

Dec, Marta, et al. "Efficacy of Experimental Phage Therapies in Livestock." Animal Health Research Reviews, 2020, pp. 1-15.
Dec M, Wernicki A, Urban-Chmiel R. Efficacy of experimental phage therapies in livestock. Anim Health Res Rev. 2020.
Dec, M., Wernicki, A., & Urban-Chmiel, R. (2020). Efficacy of experimental phage therapies in livestock. Animal Health Research Reviews, 1-15. https://doi.org/10.1017/S1466252319000161
Dec M, Wernicki A, Urban-Chmiel R. Efficacy of Experimental Phage Therapies in Livestock. Anim Health Res Rev. 2020 Jun 19;1-15. PubMed PMID: 32618543.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Efficacy of experimental phage therapies in livestock. AU - Dec,Marta, AU - Wernicki,Andrzej, AU - Urban-Chmiel,Renata, Y1 - 2020/06/19/ PY - 2020/7/4/entrez KW - Bacteriophages KW - experimental therapies KW - livestock KW - pathogens SP - 1 EP - 15 JF - Animal health research reviews JO - Anim Health Res Rev N2 - Bacteriophages are the most abundant form of life on earth and are present everywhere. The total number of bacteriophages has been estimated to be 1032 virions. The main division of bacteriophages is based on the type of nucleic acid (DNA or RNA) and on the structure of the capsid. Due to the significant increase in the number of multi-drug-resistant bacteria, bacteriophages could be a useful tool as an alternative to antibiotics in experimental therapies to prevent and to control bacterial infections in people and animals. The aim of this review was to discuss the history of phage therapy as a replacement for antibiotics, in response to EU regulations prohibiting the use of antibiotics in livestock, and to present current examples and results of experimental phage treatments in comparison to antibiotics. The use of bacteriophages to control human infections has had a high success rate, especially in mixed infections caused mainly by Staphylococcus, Pseudomonas, Enterobacter, and Enterococcus. Bacteriophages have also proven to be an effective tool in experimental treatments for combating diseases in livestock. SN - 1475-2654 UR - https://www.unboundmedicine.com/medline/citation/32618543/Efficacy_of_experimental_phage_therapies_in_livestock L2 - https://www.cambridge.org/core/product/identifier/S1466252319000161/type/journal_article DB - PRIME DP - Unbound Medicine ER -
Try the Free App:
Prime PubMed app for iOS iPhone iPad
Prime PubMed app for Android
Prime PubMed is provided
free to individuals by:
Unbound Medicine.