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Efficacy and safety results of micellar water, cream and serum for rosacea in comparison to a control group.
J Cosmet Dermatol. 2020 Jul 05 [Online ahead of print]JC

Abstract

BACKGROUND

Rosacea is a common inflammatory skin disorder with centrofacial erythema, flushing, telangiectasia, papules/pustules, and possible ocular or phymatous manifestation. Patients' skin is particularly sensitive to chemical and physical stimuli leading to burning, stinging, dryness, and skin tightness.

OBJECTIVE

Dermatological evaluation of the efficacy and safety of skin care products designed for centrofacial erythema in rosacea patients, in comparison with a control group using objective measurements. Rosacea symptoms (itching, tension, warmth, burning, dryness) and quality of life were examined.

METHODS

Sixty Caucasians with centrofacial erythema were enrolled in an 8-week prospective study, fifty of them exclusively using the study products (micellar water, cream, and serum) with ten participants randomly assigned to a control group. Patients were evaluated at baseline (V0), at 4 weeks (V1), and at 8 weeks (V2). Three-dimensional objective measurements (VECTRA®) as well as standardized questionnaires were used.

RESULTS

Results were compared with the control group. A significant reduction of 16% in skin redness as indicated by VECTRA® analysis was seen in the intervention group comparing V0-V2. Furthermore, rosacea-associated symptoms diminished by 57.1%, while life quality of affected patients within the intervention group improved by 54.5% comparing V0-V2, respectively.

CONCLUSIONS

A skin care regime suitable for sensitive and redness-prone skin led to an enhanced clinical appearance, to a decrease of associated symptoms in rosacea patients, and to an improved life quality.

Authors+Show Affiliations

Department of Dermatology and Allergy, University Hospital of Munich (LMU), Munich, Germany.Department of Dermatology and Allergy, University Hospital of Munich (LMU), Munich, Germany.Department of Dermatology and Allergy, University Hospital of Munich (LMU), Munich, Germany.LETI Pharma GmbH, Ismaning, Germany.LETI Pharma GmbH, Ismaning, Germany.Department of Dermatology and Allergy, University Hospital of Munich (LMU), Munich, Germany.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32623833

Citation

Guertler, Anne, et al. "Efficacy and Safety Results of Micellar Water, Cream and Serum for Rosacea in Comparison to a Control Group." Journal of Cosmetic Dermatology, 2020.
Guertler A, Jøntvedt NM, Clanner-Engelshofen BM, et al. Efficacy and safety results of micellar water, cream and serum for rosacea in comparison to a control group. J Cosmet Dermatol. 2020.
Guertler, A., Jøntvedt, N. M., Clanner-Engelshofen, B. M., Cappello, C., Sager, A., & Reinholz, M. (2020). Efficacy and safety results of micellar water, cream and serum for rosacea in comparison to a control group. Journal of Cosmetic Dermatology. https://doi.org/10.1111/jocd.13591
Guertler A, et al. Efficacy and Safety Results of Micellar Water, Cream and Serum for Rosacea in Comparison to a Control Group. J Cosmet Dermatol. 2020 Jul 5; PubMed PMID: 32623833.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Efficacy and safety results of micellar water, cream and serum for rosacea in comparison to a control group. AU - Guertler,Anne, AU - Jøntvedt,Nora Marie, AU - Clanner-Engelshofen,Benjamin M, AU - Cappello,Christian, AU - Sager,Angelika, AU - Reinholz,Markus, Y1 - 2020/07/05/ PY - 2020/06/03/received PY - 2020/06/22/revised PY - 2020/06/29/accepted PY - 2020/7/6/pubmed PY - 2020/7/6/medline PY - 2020/7/6/entrez KW - cosmeceutical KW - cosmetic dermatology KW - facial redness KW - rosacea KW - skin care JF - Journal of cosmetic dermatology JO - J Cosmet Dermatol N2 - BACKGROUND: Rosacea is a common inflammatory skin disorder with centrofacial erythema, flushing, telangiectasia, papules/pustules, and possible ocular or phymatous manifestation. Patients' skin is particularly sensitive to chemical and physical stimuli leading to burning, stinging, dryness, and skin tightness. OBJECTIVE: Dermatological evaluation of the efficacy and safety of skin care products designed for centrofacial erythema in rosacea patients, in comparison with a control group using objective measurements. Rosacea symptoms (itching, tension, warmth, burning, dryness) and quality of life were examined. METHODS: Sixty Caucasians with centrofacial erythema were enrolled in an 8-week prospective study, fifty of them exclusively using the study products (micellar water, cream, and serum) with ten participants randomly assigned to a control group. Patients were evaluated at baseline (V0), at 4 weeks (V1), and at 8 weeks (V2). Three-dimensional objective measurements (VECTRA®) as well as standardized questionnaires were used. RESULTS: Results were compared with the control group. A significant reduction of 16% in skin redness as indicated by VECTRA® analysis was seen in the intervention group comparing V0-V2. Furthermore, rosacea-associated symptoms diminished by 57.1%, while life quality of affected patients within the intervention group improved by 54.5% comparing V0-V2, respectively. CONCLUSIONS: A skin care regime suitable for sensitive and redness-prone skin led to an enhanced clinical appearance, to a decrease of associated symptoms in rosacea patients, and to an improved life quality. SN - 1473-2165 UR - https://www.unboundmedicine.com/medline/citation/32623833/Efficacy_and_Safety_Results_of_Micellar_Water,_Cream_and_Serum_for_Rosacea_in_comparison_to_a_control_group L2 - https://doi.org/10.1111/jocd.13591 DB - PRIME DP - Unbound Medicine ER -
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