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Progress and Challenges in the Development of COVID-19 Vaccines and Current Understanding of SARS-CoV-2- Specific Immune Responses.
J Microbiol Biotechnol. 2020 Aug 28; 30(8):1109-1115.JM

Abstract

The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is spreading globally, and the WHO has declared this outbreak a pandemic. Vaccines are an effective way to prevent the rapid spread of COVID-19. Furthermore, the immune response against SARS-CoV-2 infection needs to be understood for the development of an efficient and safe vaccine. Here, we review the current understanding of vaccine targets and the status of vaccine development for COVID-19. We also describe host immune responses to highly pathogenic human coronaviruses in terms of innate and adaptive immunities.

Authors+Show Affiliations

Center for Convergent Research of Emerging Virus Infection, Korea Research Institute of Chemical Technology, Daejeon 34114, Republic of Korea.Center for Convergent Research of Emerging Virus Infection, Korea Research Institute of Chemical Technology, Daejeon 34114, Republic of Korea.Center for Convergent Research of Emerging Virus Infection, Korea Research Institute of Chemical Technology, Daejeon 34114, Republic of Korea.Center for Convergent Research of Emerging Virus Infection, Korea Research Institute of Chemical Technology, Daejeon 34114, Republic of Korea.Center for Convergent Research of Emerging Virus Infection, Korea Research Institute of Chemical Technology, Daejeon 34114, Republic of Korea.Center for Convergent Research of Emerging Virus Infection, Korea Research Institute of Chemical Technology, Daejeon 34114, Republic of Korea.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

32627758

Citation

Kim, Kyun-Do, et al. "Progress and Challenges in the Development of COVID-19 Vaccines and Current Understanding of SARS-CoV-2- Specific Immune Responses." Journal of Microbiology and Biotechnology, vol. 30, no. 8, 2020, pp. 1109-1115.
Kim KD, Hwang I, Ku KB, et al. Progress and Challenges in the Development of COVID-19 Vaccines and Current Understanding of SARS-CoV-2- Specific Immune Responses. J Microbiol Biotechnol. 2020;30(8):1109-1115.
Kim, K. D., Hwang, I., Ku, K. B., Lee, S., Kim, S. J., & Kim, C. (2020). Progress and Challenges in the Development of COVID-19 Vaccines and Current Understanding of SARS-CoV-2- Specific Immune Responses. Journal of Microbiology and Biotechnology, 30(8), 1109-1115. https://doi.org/10.4014/jmb.2006.06006
Kim KD, et al. Progress and Challenges in the Development of COVID-19 Vaccines and Current Understanding of SARS-CoV-2- Specific Immune Responses. J Microbiol Biotechnol. 2020 Aug 28;30(8):1109-1115. PubMed PMID: 32627758.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Progress and Challenges in the Development of COVID-19 Vaccines and Current Understanding of SARS-CoV-2- Specific Immune Responses. AU - Kim,Kyun-Do, AU - Hwang,Insu, AU - Ku,Keun Bon, AU - Lee,Sumin, AU - Kim,Seong-Jun, AU - Kim,Chonsaeng, PY - 2020/06/03/received PY - 2020/06/15/revised PY - 2020/06/15/accepted PY - 2020/7/7/pubmed PY - 2020/9/4/medline PY - 2020/7/7/entrez KW - COVID-19 KW - Coronavirus KW - SARS-CoV-2 KW - immune response KW - vaccine SP - 1109 EP - 1115 JF - Journal of microbiology and biotechnology JO - J Microbiol Biotechnol VL - 30 IS - 8 N2 - The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is spreading globally, and the WHO has declared this outbreak a pandemic. Vaccines are an effective way to prevent the rapid spread of COVID-19. Furthermore, the immune response against SARS-CoV-2 infection needs to be understood for the development of an efficient and safe vaccine. Here, we review the current understanding of vaccine targets and the status of vaccine development for COVID-19. We also describe host immune responses to highly pathogenic human coronaviruses in terms of innate and adaptive immunities. SN - 1738-8872 UR - https://www.unboundmedicine.com/medline/citation/32627758/Progress_and_Challenges_in_the_Development_of_COVID_19_Vaccines_and_Current_Understanding_of_SARS_CoV_2__Specific_Immune_Responses_ L2 - http://www.jmb.or.kr/journal/view.html?doi=10.4014/jmb.2006.06006 DB - PRIME DP - Unbound Medicine ER -