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Relationship between Presence of Visceral Infarction and Functional Outcome among Patients with Acute Ischemic Stroke.
Cerebrovasc Dis. 2020; 49(3):316-320.CD

Abstract

INTRODUCTION

Evidence of visceral infarction is often found in patients with acute ischemic stroke. It remains uncertain whether there exists a relationship between visceral infarction and functional outcomes among patients with stroke.

OBJECTIVE

The aim of this study was to evaluate whether evidence of visceral infarction is associated with functional outcomes among patients with stroke.

METHODS

Among patients with acute ischemic stroke enrolled in the Cornell AcutE Stroke Academic Registry (CAESAR) from 2011 through 2016, we included those with a contrast-enhanced abdominal computed tomographic scan within 1 year of admission. Our outcome was ambulatory status at discharge from acute stroke hospitalization, categorized as walking without assistance, walking with assistance, and unable to walk. We used ordinal logistic regression to examine the association between visceral infarction and discharge ambulatory status after adjustment for demographics, stroke risk factors, stroke severity (NIH Stroke Scale), and stroke subtype.

RESULTS

Among 2,116 ischemic stroke patients registered in CAESAR from 2011 to 2016, 259 had contrast-enhanced abdominal computed tomographic imaging, of whom 48 (19%) had evidence of visceral infarction. After adjustment for demographics, stroke risk factors, stroke severity, and stroke subtype, the presence of visceral infarction was associated with a worse ambulatory status at discharge (global OR for better ambulatory status, 0.4; 95% CI, 0.2-1.0, p = 0.046).

CONCLUSIONS

We found that the presence of visceral infarction was associated with poor functional outcomes at the time of hospital discharge. These findings suggest that such findings are not necessarily benign and are at the least a marker of poor outcomes.

Authors+Show Affiliations

Clinical and Translational Neuroscience Unit, Feil Family Brain and Mind Research Institute, New York, New York, USA. Department of Neurology, Weill Cornell Medicine, New York, New York, USA.Clinical and Translational Neuroscience Unit, Feil Family Brain and Mind Research Institute, New York, New York, USA. Department of Neurology, Weill Cornell Medicine, New York, New York, USA.Clinical and Translational Neuroscience Unit, Feil Family Brain and Mind Research Institute, New York, New York, USA. Department of Radiology, Weill Cornell Medicine, New York, New York, USA.Clinical and Translational Neuroscience Unit, Feil Family Brain and Mind Research Institute, New York, New York, USA. Department of Radiology, Weill Cornell Medicine, New York, New York, USA.Clinical and Translational Neuroscience Unit, Feil Family Brain and Mind Research Institute, New York, New York, USA. Department of Neurology, Weill Cornell Medicine, New York, New York, USA.Clinical and Translational Neuroscience Unit, Feil Family Brain and Mind Research Institute, New York, New York, USA. Department of Neurology, Weill Cornell Medicine, New York, New York, USA.Clinical and Translational Neuroscience Unit, Feil Family Brain and Mind Research Institute, New York, New York, USA. Department of Neurology, Weill Cornell Medicine, New York, New York, USA.Clinical and Translational Neuroscience Unit, Feil Family Brain and Mind Research Institute, New York, New York, USA, alm9097@med.cornell.edu. Department of Neurology, Weill Cornell Medicine, New York, New York, USA, alm9097@med.cornell.edu.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32629447

Citation

Piran, Pirouz, et al. "Relationship Between Presence of Visceral Infarction and Functional Outcome Among Patients With Acute Ischemic Stroke." Cerebrovascular Diseases (Basel, Switzerland), vol. 49, no. 3, 2020, pp. 316-320.
Piran P, Atalay YB, Gupta A, et al. Relationship between Presence of Visceral Infarction and Functional Outcome among Patients with Acute Ischemic Stroke. Cerebrovasc Dis. 2020;49(3):316-320.
Piran, P., Atalay, Y. B., Gupta, A., Patel, P., Murthy, S. B., Navi, B. B., Kamel, H., & Merkler, A. E. (2020). Relationship between Presence of Visceral Infarction and Functional Outcome among Patients with Acute Ischemic Stroke. Cerebrovascular Diseases (Basel, Switzerland), 49(3), 316-320. https://doi.org/10.1159/000508826
Piran P, et al. Relationship Between Presence of Visceral Infarction and Functional Outcome Among Patients With Acute Ischemic Stroke. Cerebrovasc Dis. 2020;49(3):316-320. PubMed PMID: 32629447.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Relationship between Presence of Visceral Infarction and Functional Outcome among Patients with Acute Ischemic Stroke. AU - Piran,Pirouz, AU - Atalay,Yahya B, AU - Gupta,Ajay, AU - Patel,Praneil, AU - Murthy,Santosh B, AU - Navi,Babak B, AU - Kamel,Hooman, AU - Merkler,Alexander E, Y1 - 2020/07/06/ PY - 2020/03/19/received PY - 2020/05/06/accepted PY - 2020/7/7/pubmed PY - 2020/7/7/medline PY - 2020/7/7/entrez KW - Cardioembolism KW - Functional outcomes KW - Renal infarction KW - Splenic infarction KW - Stroke KW - Visceral infarction SP - 316 EP - 320 JF - Cerebrovascular diseases (Basel, Switzerland) JO - Cerebrovasc. Dis. VL - 49 IS - 3 N2 - INTRODUCTION: Evidence of visceral infarction is often found in patients with acute ischemic stroke. It remains uncertain whether there exists a relationship between visceral infarction and functional outcomes among patients with stroke. OBJECTIVE: The aim of this study was to evaluate whether evidence of visceral infarction is associated with functional outcomes among patients with stroke. METHODS: Among patients with acute ischemic stroke enrolled in the Cornell AcutE Stroke Academic Registry (CAESAR) from 2011 through 2016, we included those with a contrast-enhanced abdominal computed tomographic scan within 1 year of admission. Our outcome was ambulatory status at discharge from acute stroke hospitalization, categorized as walking without assistance, walking with assistance, and unable to walk. We used ordinal logistic regression to examine the association between visceral infarction and discharge ambulatory status after adjustment for demographics, stroke risk factors, stroke severity (NIH Stroke Scale), and stroke subtype. RESULTS: Among 2,116 ischemic stroke patients registered in CAESAR from 2011 to 2016, 259 had contrast-enhanced abdominal computed tomographic imaging, of whom 48 (19%) had evidence of visceral infarction. After adjustment for demographics, stroke risk factors, stroke severity, and stroke subtype, the presence of visceral infarction was associated with a worse ambulatory status at discharge (global OR for better ambulatory status, 0.4; 95% CI, 0.2-1.0, p = 0.046). CONCLUSIONS: We found that the presence of visceral infarction was associated with poor functional outcomes at the time of hospital discharge. These findings suggest that such findings are not necessarily benign and are at the least a marker of poor outcomes. SN - 1421-9786 UR - https://www.unboundmedicine.com/medline/citation/32629447/Relationship_between_Presence_of_Visceral_Infarction_and_Functional_Outcome_among_Patients_with_Acute_Ischemic_Stroke L2 - https://www.karger.com?DOI=10.1159/000508826 DB - PRIME DP - Unbound Medicine ER -
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