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Smoking history and its relationship with comorbidities in patients with obstructive sleep apnea.
Tob Induc Dis. 2020; 18:56.TI

Abstract

INTRODUCTION

Current knowledge on the correlation between smoking and comorbidities associated with obstructive sleep apnea (OSA) is limited. This study evaluated the smoking history of OSA patients and analyzed the association between smoking and OSA comorbidities.

METHODS

Retrospective analysis was performed in newly diagnosed OSA patients in our hospital, a tertiary medical center, from January 2016 to December 2019. In all, 1021 patients were enrolled and divided into two groups, non-smokers (n=796) and current/former smokers (n=225), in order to compare their clinical manifestations and polysomnographic results and to analyze the association between smoking and comorbidities.

RESULTS

Compared with the non-smokers, the current/former smokers had higher Epworth sleepiness scale (ESS) scores (9.3 ± 4.0 vs 8.5 ± 5.1; p<0.05), longer sleep latency (SL) [20.5 (12.3-39.3) vs 18.5 (10.0-34.0) minutes; p<0.05], and a lower nocturnal mean oxygen saturation (91.8 ± 3.6% vs 92.8 ± 3.4%; p<0.001). There was no significant difference in the apnea-hypopnea index (AHI) between the two groups. OSA patients with a history of smoking had significantly increased risk of hypertension (OR=2.09; 95% CI: 1.46- 3.01), chronic obstructive pulmonary disease (COPD) (OR=9.80; 95% CI: 4.73-20.33), gastroesophageal reflux disease (GERD) (OR=1.97; 95% CI: 1.19-3.27), and chronic pharyngitis (OR=1.83; 95% CI: 1.32-2.54).

CONCLUSIONS

No significant association was found between previous smoking history and current OSA severity. OSA patients with a history of smoking had an increased risk of hypertension, COPD, GERD, and chronic pharyngitis.

Authors+Show Affiliations

Department of Pulmonary and Critical Care Medicine, Ningbo Medical Center Lihuili Hospital, Ningbo, China. Department of Special Procurement Ward, The First Affiliated Hospital of Soochow University, Suzhou, China. Department of General Practice, The First Affiliated Hospital of Soochow University, Suzhou, China.Department of Special Procurement Ward, The First Affiliated Hospital of Soochow University, Suzhou, China. Department of General Practice, The First Affiliated Hospital of Soochow University, Suzhou, China.Department of Pulmonary and Critical Care Medicine, Ningbo Medical Center Lihuili Hospital, Ningbo, China.Department of Pulmonary and Critical Care Medicine, Ningbo Medical Center Lihuili Hospital, Ningbo, China.Sleep Medicine Center, Nanfang Hospital, Southern Medical University, Guangzhou, China. Department of Pulmonary and Critical Care Medicine, Ningbo Yinzhou No. 2 Hospital, Ningbo, China.Department of Special Procurement Ward, The First Affiliated Hospital of Soochow University, Suzhou, China. Department of General Practice, The First Affiliated Hospital of Soochow University, Suzhou, China.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32641922

Citation

Shao, Chuan, et al. "Smoking History and Its Relationship With Comorbidities in Patients With Obstructive Sleep Apnea." Tobacco Induced Diseases, vol. 18, 2020, p. 56.
Shao C, Qi H, Fang Q, et al. Smoking history and its relationship with comorbidities in patients with obstructive sleep apnea. Tob Induc Dis. 2020;18:56.
Shao, C., Qi, H., Fang, Q., Tu, J., Li, Q., & Wang, L. (2020). Smoking history and its relationship with comorbidities in patients with obstructive sleep apnea. Tobacco Induced Diseases, 18, 56. https://doi.org/10.18332/tid/123429
Shao C, et al. Smoking History and Its Relationship With Comorbidities in Patients With Obstructive Sleep Apnea. Tob Induc Dis. 2020;18:56. PubMed PMID: 32641922.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Smoking history and its relationship with comorbidities in patients with obstructive sleep apnea. AU - Shao,Chuan, AU - Qi,Huan, AU - Fang,Qing, AU - Tu,Jinjing, AU - Li,Qianjun, AU - Wang,Ling, Y1 - 2020/07/01/ PY - 2020/04/17/received PY - 2020/05/26/revised PY - 2020/06/03/accepted PY - 2020/7/10/entrez PY - 2020/7/10/pubmed PY - 2020/7/10/medline KW - comorbidities KW - obstructive sleep apnea KW - polysomnography KW - smoking SP - 56 EP - 56 JF - Tobacco induced diseases JO - Tob Induc Dis VL - 18 N2 - INTRODUCTION: Current knowledge on the correlation between smoking and comorbidities associated with obstructive sleep apnea (OSA) is limited. This study evaluated the smoking history of OSA patients and analyzed the association between smoking and OSA comorbidities. METHODS: Retrospective analysis was performed in newly diagnosed OSA patients in our hospital, a tertiary medical center, from January 2016 to December 2019. In all, 1021 patients were enrolled and divided into two groups, non-smokers (n=796) and current/former smokers (n=225), in order to compare their clinical manifestations and polysomnographic results and to analyze the association between smoking and comorbidities. RESULTS: Compared with the non-smokers, the current/former smokers had higher Epworth sleepiness scale (ESS) scores (9.3 ± 4.0 vs 8.5 ± 5.1; p<0.05), longer sleep latency (SL) [20.5 (12.3-39.3) vs 18.5 (10.0-34.0) minutes; p<0.05], and a lower nocturnal mean oxygen saturation (91.8 ± 3.6% vs 92.8 ± 3.4%; p<0.001). There was no significant difference in the apnea-hypopnea index (AHI) between the two groups. OSA patients with a history of smoking had significantly increased risk of hypertension (OR=2.09; 95% CI: 1.46- 3.01), chronic obstructive pulmonary disease (COPD) (OR=9.80; 95% CI: 4.73-20.33), gastroesophageal reflux disease (GERD) (OR=1.97; 95% CI: 1.19-3.27), and chronic pharyngitis (OR=1.83; 95% CI: 1.32-2.54). CONCLUSIONS: No significant association was found between previous smoking history and current OSA severity. OSA patients with a history of smoking had an increased risk of hypertension, COPD, GERD, and chronic pharyngitis. SN - 1617-9625 UR - https://www.unboundmedicine.com/medline/citation/32641922/Smoking_history_and_its_relationship_with_comorbidities_in_patients_with_obstructive_sleep_apnea L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/32641922/ DB - PRIME DP - Unbound Medicine ER -
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