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[Pyogenic spondylodiscitis: symptoms, diagnostics and therapeutic strategies].
Orthopade. 2020 Aug; 49(8):691-701.O

Abstract

BACKGROUND

Pyogenic spondylodiscitis is a rare disease that is being diagnosed with increasing frequency in recent years. It is associated with a high morbidity and mortality.

DIAGNOSIS

Often, because of its nonspecific symptoms, pyogenic spondylodiscitis is diagnose with some delay. In addition to pathogen detection, MRI is the gold standard to diagnose pyogenic spondylodiscitis. Also, x-ray imaging and CT can be carried out for surgical planning and for subsequent follow-up imaging. If blood or tissue cultures are negative, open surgical biopsies should be preferred over CT-guided biopsies.

THERAPY

The therapy can be conservative, such as immobilization, as well as antibiotics and analgesics, or surgical. If, for example, neurological deficits, spinale instabilities or deformities, septic disease progression or extensive abscess formations are present, surgical therapy is indicated. The surgical treatment strategies depend on the severity of the disease.

OUTLOOK

The prognosis is dependent on a rapid diagnosis and a swift start to therapy. There is no clear evidence with regard to treatment options (conservative vs. surgical therapy).

Authors+Show Affiliations

Klinik für Neurochirurgie und Zentrum für Wirbelsäulentherapie, Helios Klinikum Berlin-Buch, Schwanebecker Chaussee 50, 13125, Berlin, Deutschland. yu-mi.ryang@helios-gesundheit.de.Clinic für Wirbelsäulenerkrankungen und -Therapien, MEOCLINIC, Berlin, Deutschland.

Pub Type(s)

English Abstract
Journal Article
Review

Language

ger

PubMed ID

32642943

Citation

Ryang, Y-M, and M Akbar. "[Pyogenic Spondylodiscitis: Symptoms, Diagnostics and Therapeutic Strategies]." Der Orthopade, vol. 49, no. 8, 2020, pp. 691-701.
Ryang YM, Akbar M. [Pyogenic spondylodiscitis: symptoms, diagnostics and therapeutic strategies]. Orthopade. 2020;49(8):691-701.
Ryang, Y. M., & Akbar, M. (2020). [Pyogenic spondylodiscitis: symptoms, diagnostics and therapeutic strategies]. Der Orthopade, 49(8), 691-701. https://doi.org/10.1007/s00132-020-03945-1
Ryang YM, Akbar M. [Pyogenic Spondylodiscitis: Symptoms, Diagnostics and Therapeutic Strategies]. Orthopade. 2020;49(8):691-701. PubMed PMID: 32642943.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Pyogenic spondylodiscitis: symptoms, diagnostics and therapeutic strategies]. AU - Ryang,Y-M, AU - Akbar,M, PY - 2020/7/10/pubmed PY - 2020/7/10/medline PY - 2020/7/10/entrez KW - Antibiotics KW - Biopsy KW - Discitis KW - Spinal infection KW - Therapy, conservative or surgical SP - 691 EP - 701 JF - Der Orthopade JO - Orthopade VL - 49 IS - 8 N2 - BACKGROUND: Pyogenic spondylodiscitis is a rare disease that is being diagnosed with increasing frequency in recent years. It is associated with a high morbidity and mortality. DIAGNOSIS: Often, because of its nonspecific symptoms, pyogenic spondylodiscitis is diagnose with some delay. In addition to pathogen detection, MRI is the gold standard to diagnose pyogenic spondylodiscitis. Also, x-ray imaging and CT can be carried out for surgical planning and for subsequent follow-up imaging. If blood or tissue cultures are negative, open surgical biopsies should be preferred over CT-guided biopsies. THERAPY: The therapy can be conservative, such as immobilization, as well as antibiotics and analgesics, or surgical. If, for example, neurological deficits, spinale instabilities or deformities, septic disease progression or extensive abscess formations are present, surgical therapy is indicated. The surgical treatment strategies depend on the severity of the disease. OUTLOOK: The prognosis is dependent on a rapid diagnosis and a swift start to therapy. There is no clear evidence with regard to treatment options (conservative vs. surgical therapy). SN - 1433-0431 UR - https://www.unboundmedicine.com/medline/citation/32642943/[Pyogenic_spondylodiscitis:_symptoms,_diagnostics_and_therapeutic_strategies] L2 - https://dx.doi.org/10.1007/s00132-020-03945-1 DB - PRIME DP - Unbound Medicine ER -
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