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The Efficacy of Intravenous Insulin Infusion in the Management of Hypertriglyceridemia-Induced Pancreatitis in a Rural Community Hospital.
J Investig Med High Impact Case Rep. 2020 Jan-Dec; 8:2324709620940492.JI

Abstract

A 28-year-old female presented to the emergency room with epigastric pain, nausea, and vomiting; her lipase was elevated, and computed tomography of abdomen showed evidence of acute pancreatitis. Her past medical history was significant for poorly controlled insulin requiring type 2 diabetes mellitus and 2 previous admissions for hypertriglyceridemia-induced pancreatitis. Due to the severity of her pancreatitis presentation, she was admitted to the intensive care unit. She received aggressive intravenous fluid hydration and was started on an insulin drip. Apheresis was strongly considered given the degree of her hypertriglyceridemia (11 602 mg/dL), but there was no timely access to this treatment option. She, however, significantly improved with insulin therapy alone. Her triglyceride levels decreased rather quickly to 4783 mg/dL within 24 hours and by the fourth day of admission were comfortably <1000 mg/dL with insulin infusion along with clinical improvement. She was discharged on niacin and insulin therapy along with her home medications of statin and fenofibrate.

Authors+Show Affiliations

White River Health System, Batesville, AR, USA.White River Health System, Batesville, AR, USA.White River Health System, Batesville, AR, USA.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32643965

Citation

Sawalha, Khalid, et al. "The Efficacy of Intravenous Insulin Infusion in the Management of Hypertriglyceridemia-Induced Pancreatitis in a Rural Community Hospital." Journal of Investigative Medicine High Impact Case Reports, vol. 8, 2020, p. 2324709620940492.
Sawalha K, Kunnumpurath A, Kamoga GR. The Efficacy of Intravenous Insulin Infusion in the Management of Hypertriglyceridemia-Induced Pancreatitis in a Rural Community Hospital. J Investig Med High Impact Case Rep. 2020;8:2324709620940492.
Sawalha, K., Kunnumpurath, A., & Kamoga, G. R. (2020). The Efficacy of Intravenous Insulin Infusion in the Management of Hypertriglyceridemia-Induced Pancreatitis in a Rural Community Hospital. Journal of Investigative Medicine High Impact Case Reports, 8, 2324709620940492. https://doi.org/10.1177/2324709620940492
Sawalha K, Kunnumpurath A, Kamoga GR. The Efficacy of Intravenous Insulin Infusion in the Management of Hypertriglyceridemia-Induced Pancreatitis in a Rural Community Hospital. J Investig Med High Impact Case Rep. 2020 Jan-Dec;8:2324709620940492. PubMed PMID: 32643965.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The Efficacy of Intravenous Insulin Infusion in the Management of Hypertriglyceridemia-Induced Pancreatitis in a Rural Community Hospital. AU - Sawalha,Khalid, AU - Kunnumpurath,Anthony, AU - Kamoga,Gilbert-Roy, PY - 2020/7/10/entrez PY - 2020/7/10/pubmed PY - 2020/7/10/medline KW - cost-effective KW - hypertriglyceridemia KW - insulin KW - pancreatitis SP - 2324709620940492 EP - 2324709620940492 JF - Journal of investigative medicine high impact case reports JO - J Investig Med High Impact Case Rep VL - 8 N2 - A 28-year-old female presented to the emergency room with epigastric pain, nausea, and vomiting; her lipase was elevated, and computed tomography of abdomen showed evidence of acute pancreatitis. Her past medical history was significant for poorly controlled insulin requiring type 2 diabetes mellitus and 2 previous admissions for hypertriglyceridemia-induced pancreatitis. Due to the severity of her pancreatitis presentation, she was admitted to the intensive care unit. She received aggressive intravenous fluid hydration and was started on an insulin drip. Apheresis was strongly considered given the degree of her hypertriglyceridemia (11 602 mg/dL), but there was no timely access to this treatment option. She, however, significantly improved with insulin therapy alone. Her triglyceride levels decreased rather quickly to 4783 mg/dL within 24 hours and by the fourth day of admission were comfortably <1000 mg/dL with insulin infusion along with clinical improvement. She was discharged on niacin and insulin therapy along with her home medications of statin and fenofibrate. SN - 2324-7096 UR - https://www.unboundmedicine.com/medline/citation/32643965/The_Efficacy_of_Intravenous_Insulin_Infusion_in_the_Management_of_Hypertriglyceridemia-Induced_Pancreatitis_in_a_Rural_Community_Hospital L2 - https://journals.sagepub.com/doi/10.1177/2324709620940492?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub=www.ncbi.nlm.nih.gov DB - PRIME DP - Unbound Medicine ER -
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