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Fenofibrate

Abstract
Fenofibrate is FDA approved for the management and treatment of hypertriglyceridemia, primary hypercholesterolemia or mixed dyslipidemia. It reduces low-density lipoprotein, triglycerides, and total cholesterol while increasing high-density lipoprotein cholesterol in adults. Fenofibrate should be used in conjunction with a restriction of cholesterol intake and exercise if lifestyle modifications alone have been insufficient. The clinician needs to rule out hyperlipidemia or dyslipidemia due to secondary causes before initiating treatment. The medication is safe and effective for use in the geriatric population. However, drug safety and efficacy are unestablished in the pediatrics population. Fenobrifate may be used in pregnancy if the potential benefits outweigh the potential risk to the fetus. Off-label fenofibrate may be used as adjunctive therapy for elevated blood uric acid levels in individuals with gout.[1][2]

Publisher

StatPearls Publishing
Treasure Island (FL)

Language

eng

PubMed ID

32644645

Citation

Sidhu G, Tripp J: Fenofibrate. StatPearls. StatPearls Publishing, 2020, Treasure Island (FL).
Sidhu G, Tripp J. Fenofibrate. StatPearls. StatPearls Publishing; 2020.
Sidhu G & Tripp J. (2020). Fenofibrate. In StatPearls. Treasure Island (FL): StatPearls Publishing
Sidhu G, Tripp J. Fenofibrate. StatPearls. Treasure Island (FL): StatPearls Publishing; 2020.
* Article titles in AMA citation format should be in sentence-case
TY - CHAP T1 - Fenofibrate BT - StatPearls A1 - Sidhu,Gursharan, AU - Tripp,Jayson, Y1 - 2020/01// PY - 2020/7/10/pubmed PY - 2020/7/10/medline PY - 2020/7/10/entrez N2 - Fenofibrate is FDA approved for the management and treatment of hypertriglyceridemia, primary hypercholesterolemia or mixed dyslipidemia. It reduces low-density lipoprotein, triglycerides, and total cholesterol while increasing high-density lipoprotein cholesterol in adults. Fenofibrate should be used in conjunction with a restriction of cholesterol intake and exercise if lifestyle modifications alone have been insufficient. The clinician needs to rule out hyperlipidemia or dyslipidemia due to secondary causes before initiating treatment. The medication is safe and effective for use in the geriatric population. However, drug safety and efficacy are unestablished in the pediatrics population. Fenobrifate may be used in pregnancy if the potential benefits outweigh the potential risk to the fetus. Off-label fenofibrate may be used as adjunctive therapy for elevated blood uric acid levels in individuals with gout.[1][2] PB - StatPearls Publishing CY - Treasure Island (FL) UR - https://www.unboundmedicine.com/medline/citation/32644645/StatPearls:_Fenofibrate L2 - https://www.ncbi.nlm.nih.gov/books/NBK559219 DB - PRIME DP - Unbound Medicine ER -
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