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Electro-acupuncture regulates glucose metabolism in chronic stress model rats.
Sci Rep. 2020 Jul 09; 10(1):11281.SR

Abstract

Studies have shown that acupuncture is very effective in treating chronic stress depression. However, little is known about the therapeutic mechanism of electro-acupuncture. Metabolomics, on the other hand, is a technology that determines the metabolic changes of organisms caused by various interventions as a whole and is related to the overall effect of electro-acupuncture (EA). 1HNMR, serum sample analysis, and histopathology and molecular biology analysis were used to evaluate the effects of EA. The results show that electro-acupuncture points can regulate the heat pain threshold of chronic stress model rats and change the morphology of adrenal cortex cells Structure, and regulate the contents of corticotropin-releasing hormone, Corticosterone (CORT), glucose, alanine and valine in the samples. These findings help to clarify the therapeutic mechanism of electro-acupuncture on heterologous chronic stress model rats. The effect of electro-acupuncture on improving chronic stress is likely to be achieved by regulating glucose metabolism, which can provide a reference for clinical acupuncture treatment of chronic stress depression.

Authors+Show Affiliations

Luoyang Traditional Chinese Medicine Hospital, Luoyang, 471000, People's Republic of China. Godlovehorse@163.com. Department of Traditional Chinese Medicine, Xiamen University, Xiamen, 361005, People's Republic of China. Godlovehorse@163.com.Luoyang Traditional Chinese Medicine Hospital, Luoyang, 471000, People's Republic of China.Luoyang Traditional Chinese Medicine Hospital, Luoyang, 471000, People's Republic of China.Department of Traditional Chinese Medicine, Xiamen University, Xiamen, 361005, People's Republic of China.Shanghai Research Institute of Acupuncture and Meridian, Shanghai, 200030, People's Republic of China.Luoyang Traditional Chinese Medicine Hospital, Luoyang, 471000, People's Republic of China.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32647204

Citation

Ma, Fu-Qiang, et al. "Electro-acupuncture Regulates Glucose Metabolism in Chronic Stress Model Rats." Scientific Reports, vol. 10, no. 1, 2020, p. 11281.
Ma FQ, Sun CJ, Wei JJ, et al. Electro-acupuncture regulates glucose metabolism in chronic stress model rats. Sci Rep. 2020;10(1):11281.
Ma, F. Q., Sun, C. J., Wei, J. J., Wang, Y. D., Shen, J. C., & Chang, J. J. (2020). Electro-acupuncture regulates glucose metabolism in chronic stress model rats. Scientific Reports, 10(1), 11281. https://doi.org/10.1038/s41598-020-68132-w
Ma FQ, et al. Electro-acupuncture Regulates Glucose Metabolism in Chronic Stress Model Rats. Sci Rep. 2020 Jul 9;10(1):11281. PubMed PMID: 32647204.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Electro-acupuncture regulates glucose metabolism in chronic stress model rats. AU - Ma,Fu-Qiang, AU - Sun,Chan-Juan, AU - Wei,Jun-Jie, AU - Wang,Ya-Dong, AU - Shen,Jia-Cheng, AU - Chang,Jin-Jian, Y1 - 2020/07/09/ PY - 2019/12/26/received PY - 2020/06/17/accepted PY - 2020/7/11/entrez PY - 2020/7/11/pubmed PY - 2020/7/11/medline SP - 11281 EP - 11281 JF - Scientific reports JO - Sci Rep VL - 10 IS - 1 N2 - Studies have shown that acupuncture is very effective in treating chronic stress depression. However, little is known about the therapeutic mechanism of electro-acupuncture. Metabolomics, on the other hand, is a technology that determines the metabolic changes of organisms caused by various interventions as a whole and is related to the overall effect of electro-acupuncture (EA). 1HNMR, serum sample analysis, and histopathology and molecular biology analysis were used to evaluate the effects of EA. The results show that electro-acupuncture points can regulate the heat pain threshold of chronic stress model rats and change the morphology of adrenal cortex cells Structure, and regulate the contents of corticotropin-releasing hormone, Corticosterone (CORT), glucose, alanine and valine in the samples. These findings help to clarify the therapeutic mechanism of electro-acupuncture on heterologous chronic stress model rats. The effect of electro-acupuncture on improving chronic stress is likely to be achieved by regulating glucose metabolism, which can provide a reference for clinical acupuncture treatment of chronic stress depression. SN - 2045-2322 UR - https://www.unboundmedicine.com/medline/citation/32647204/Electro-acupuncture_regulates_glucose_metabolism_in_chronic_stress_model_rats L2 - http://dx.doi.org/10.1038/s41598-020-68132-w DB - PRIME DP - Unbound Medicine ER -
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