Tags

Type your tag names separated by a space and hit enter

MicroRNA Regulatory Pathways in the Control of the Actin-Myosin Cytoskeleton.
Cells. 2020 Jul 09; 9(7)C

Abstract

MicroRNAs (miRNAs) are key modulators of post-transcriptional gene regulation in a plethora of processes, including actin-myosin cytoskeleton dynamics. Recent evidence points to the widespread effects of miRNAs on actin-myosin cytoskeleton dynamics, either directly on the expression of actin and myosin genes or indirectly on the diverse signaling cascades modulating cytoskeletal arrangement. Furthermore, studies from various human models indicate that miRNAs contribute to the development of various human disorders. The potentially huge impact of miRNA-based mechanisms on cytoskeletal elements is just starting to be recognized. In this review, we summarize recent knowledge about the importance of microRNA modulation of the actin-myosin cytoskeleton affecting physiological processes, including cardiovascular function, hematopoiesis, podocyte physiology, and osteogenesis.

Authors+Show Affiliations

Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

32660059

Citation

Uray, Karen, et al. "MicroRNA Regulatory Pathways in the Control of the Actin-Myosin Cytoskeleton." Cells, vol. 9, no. 7, 2020.
Uray K, Major E, Lontay B. MicroRNA Regulatory Pathways in the Control of the Actin-Myosin Cytoskeleton. Cells. 2020;9(7).
Uray, K., Major, E., & Lontay, B. (2020). MicroRNA Regulatory Pathways in the Control of the Actin-Myosin Cytoskeleton. Cells, 9(7). https://doi.org/10.3390/cells9071649
Uray K, Major E, Lontay B. MicroRNA Regulatory Pathways in the Control of the Actin-Myosin Cytoskeleton. Cells. 2020 Jul 9;9(7) PubMed PMID: 32660059.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - MicroRNA Regulatory Pathways in the Control of the Actin-Myosin Cytoskeleton. AU - Uray,Karen, AU - Major,Evelin, AU - Lontay,Beata, Y1 - 2020/07/09/ PY - 2020/06/11/received PY - 2020/07/03/revised PY - 2020/07/07/accepted PY - 2020/7/15/entrez KW - Rho kinase KW - actin KW - actin–myosin complex KW - cancer KW - cardiovascular system KW - gene expression KW - hematopoiesis KW - miRNA KW - muscle cell differentiation KW - myosin KW - smooth muscle KW - stress fiber KW - striated muscle KW - therapy JF - Cells JO - Cells VL - 9 IS - 7 N2 - MicroRNAs (miRNAs) are key modulators of post-transcriptional gene regulation in a plethora of processes, including actin-myosin cytoskeleton dynamics. Recent evidence points to the widespread effects of miRNAs on actin-myosin cytoskeleton dynamics, either directly on the expression of actin and myosin genes or indirectly on the diverse signaling cascades modulating cytoskeletal arrangement. Furthermore, studies from various human models indicate that miRNAs contribute to the development of various human disorders. The potentially huge impact of miRNA-based mechanisms on cytoskeletal elements is just starting to be recognized. In this review, we summarize recent knowledge about the importance of microRNA modulation of the actin-myosin cytoskeleton affecting physiological processes, including cardiovascular function, hematopoiesis, podocyte physiology, and osteogenesis. SN - 2073-4409 UR - https://www.unboundmedicine.com/medline/citation/32660059/MicroRNA_Regulatory_Pathways_in_the_Control_of_the_Actin-Myosin_Cytoskeleton L2 - https://www.mdpi.com/resolver?pii=cells9071649 DB - PRIME DP - Unbound Medicine ER -
Try the Free App:
Prime PubMed app for iOS iPhone iPad
Prime PubMed app for Android
Prime PubMed is provided
free to individuals by:
Unbound Medicine.