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SARS-COV-2 in Ophthalmology: Current Evidence and Standards for Clinical Practice.
Acta Med Port. 2020 Sep 01; 33(9):593-600.AM

Abstract

INTRODUCTION

COVID-19 is caused by the coronavirus SARS-CoV-2. Ocular manifestations have been reported including conjunctivitis and retinal changes. Therefore, it is of the utmost importance to clarify eye involvement in COVID-19 in order to help with its diagnosis and to further prevent its transmission. The purpose of this review is to describe the structure and transmission of SARS-CoV-2, reported ocular findings and protection strategies for ophthalmologists.

MATERIAL AND METHODS

Literature search on PubMed for relevant articles using the keywords 'COVID-19', 'coronavirus', and 'SARS-CoV-2' in conjunction with 'ophthalmology' and 'eye'. Moreover, official recommendations of ophthalmological societies were reviewed.

RESULTS

Although the conjunctiva is directly exposed to extraocular pathogens, and the mucosa of the ocular surface and upper respiratory tract are connected by the nasolacrimal duct, the eye is rarely involved in human SARS-CoV-2 infection and the SARS-CoV-2 RNA positive rate by RT-PCR test in tears and conjunctival secretions from patients with COVID-19 is also extremely low.

DISCUSSION

The eye can be affected by SARS-CoV-2, which is supported by some reports of conjunctivitis and retinal changes, but its role in the spread of the disease is still unknown.

CONCLUSION

Given the current scarce evidence, more research is needed to clarify the relationship between SARS-CoV-2 and the eye.

Authors+Show Affiliations

Department of Ophthalmology. Centro Hospitalar Universitário de São João. Porto. Portugal.Department of Ophthalmology. Centro Hospitalar Universitário de São João. Porto. Portugal.Department of Ophthalmology. Centro Hospitalar Universitário de São João. Porto. Department of Surgery and Physiology. Faculty of Medicine. University of Porto. Porto. Portugal.Department of Ophthalmology. Centro Hospitalar Universitário de São João. Porto. Department of Surgery and Physiology. Faculty of Medicine. University of Porto. Porto. Portugal.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

32662416

Citation

Torres-Costa, Sónia, et al. "SARS-COV-2 in Ophthalmology: Current Evidence and Standards for Clinical Practice." Acta Medica Portuguesa, vol. 33, no. 9, 2020, pp. 593-600.
Torres-Costa S, Lima-Fontes M, Falcão-Reis F, et al. SARS-COV-2 in Ophthalmology: Current Evidence and Standards for Clinical Practice. Acta Med Port. 2020;33(9):593-600.
Torres-Costa, S., Lima-Fontes, M., Falcão-Reis, F., & Falcão, M. (2020). SARS-COV-2 in Ophthalmology: Current Evidence and Standards for Clinical Practice. Acta Medica Portuguesa, 33(9), 593-600. https://doi.org/10.20344/amp.14118
Torres-Costa S, et al. SARS-COV-2 in Ophthalmology: Current Evidence and Standards for Clinical Practice. Acta Med Port. 2020 Sep 1;33(9):593-600. PubMed PMID: 32662416.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - SARS-COV-2 in Ophthalmology: Current Evidence and Standards for Clinical Practice. AU - Torres-Costa,Sónia, AU - Lima-Fontes,Mário, AU - Falcão-Reis,Fernando, AU - Falcão,Manuel, Y1 - 2020/06/16/ PY - 2020/05/13/received PY - 2020/06/16/accepted PY - 2020/06/09/revised PY - 2020/7/15/pubmed PY - 2020/11/20/medline PY - 2020/7/15/entrez KW - COVID-19 KW - Conjunctivitis KW - Coronavirus Infections KW - Eye Diseases KW - Ophthalmology KW - SARS-COV-2 SP - 593 EP - 600 JF - Acta medica portuguesa JO - Acta Med Port VL - 33 IS - 9 N2 - INTRODUCTION: COVID-19 is caused by the coronavirus SARS-CoV-2. Ocular manifestations have been reported including conjunctivitis and retinal changes. Therefore, it is of the utmost importance to clarify eye involvement in COVID-19 in order to help with its diagnosis and to further prevent its transmission. The purpose of this review is to describe the structure and transmission of SARS-CoV-2, reported ocular findings and protection strategies for ophthalmologists. MATERIAL AND METHODS: Literature search on PubMed for relevant articles using the keywords 'COVID-19', 'coronavirus', and 'SARS-CoV-2' in conjunction with 'ophthalmology' and 'eye'. Moreover, official recommendations of ophthalmological societies were reviewed. RESULTS: Although the conjunctiva is directly exposed to extraocular pathogens, and the mucosa of the ocular surface and upper respiratory tract are connected by the nasolacrimal duct, the eye is rarely involved in human SARS-CoV-2 infection and the SARS-CoV-2 RNA positive rate by RT-PCR test in tears and conjunctival secretions from patients with COVID-19 is also extremely low. DISCUSSION: The eye can be affected by SARS-CoV-2, which is supported by some reports of conjunctivitis and retinal changes, but its role in the spread of the disease is still unknown. CONCLUSION: Given the current scarce evidence, more research is needed to clarify the relationship between SARS-CoV-2 and the eye. SN - 1646-0758 UR - https://www.unboundmedicine.com/medline/citation/32662416/SARS_COV_2_in_Ophthalmology:_Current_Evidence_and_Standards_for_Clinical_Practice_ L2 - http://www.diseaseinfosearch.org/result/6415 DB - PRIME DP - Unbound Medicine ER -