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[Endoscopic sclerotherapy and esophageal varices].
Schweiz Med Wochenschr. 1988 Oct 15; 118(41):1476-81.SM

Abstract

60 consecutive patients underwent sclerotherapy for hemorrhage from ruptured esophageal varices. Sclerosis was always started within the first 48 hours. 12 patients (20%) died during initial hospitalization, but only 5 from recurrent bleeding. Of 48 survivors, 22 (46%) did not rebleed during a mean 18-month follow-up, whereas 26 (54%) had recurrences, 27 of these bleeding episodes occurred early (within 4 months) and 17 late (mean 16.5 months). Eradication of the varices was achieved in 29 patients (60%) with a mean of 6.2 sessions and within a mean of 6 months. Of these 48 patients 2 have been lost to follow-up, 25 (52%) are alive after a mean follow-up of 29 months, and 21 (44%) died (though only 2 from variceal bleeding). The survival curve (Kaplan-Meier) of these 60 bleeders is 45% and 37% at 2 and 4 years respectively. Sclerotherapy caused no death and only minor adverse effects. These results confirm those in the literature. We advocate endoscopic sclerosis as first choice in the treatment of ruptured esophageal varices.

Authors+Show Affiliations

Division de gastroentérologie et nutrition, Hôpital cantonal universitaire de Genève.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

fre

PubMed ID

3266368

Citation

Berclaz, R, et al. "[Endoscopic Sclerotherapy and Esophageal Varices]." Schweizerische Medizinische Wochenschrift, vol. 118, no. 41, 1988, pp. 1476-81.
Berclaz R, de Peyer R, Miazza B, et al. [Endoscopic sclerotherapy and esophageal varices]. Schweiz Med Wochenschr. 1988;118(41):1476-81.
Berclaz, R., de Peyer, R., Miazza, B., Laszlo, A., Cunningham, M., Dederding, J. P., Loup, R., & Loizeau, E. (1988). [Endoscopic sclerotherapy and esophageal varices]. Schweizerische Medizinische Wochenschrift, 118(41), 1476-81.
Berclaz R, et al. [Endoscopic Sclerotherapy and Esophageal Varices]. Schweiz Med Wochenschr. 1988 Oct 15;118(41):1476-81. PubMed PMID: 3266368.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Endoscopic sclerotherapy and esophageal varices]. AU - Berclaz,R, AU - de Peyer,R, AU - Miazza,B, AU - Laszlo,A, AU - Cunningham,M, AU - Dederding,J P, AU - Loup,R, AU - Loizeau,E, PY - 1988/10/15/pubmed PY - 1988/10/15/medline PY - 1988/10/15/entrez SP - 1476 EP - 81 JF - Schweizerische medizinische Wochenschrift JO - Schweiz Med Wochenschr VL - 118 IS - 41 N2 - 60 consecutive patients underwent sclerotherapy for hemorrhage from ruptured esophageal varices. Sclerosis was always started within the first 48 hours. 12 patients (20%) died during initial hospitalization, but only 5 from recurrent bleeding. Of 48 survivors, 22 (46%) did not rebleed during a mean 18-month follow-up, whereas 26 (54%) had recurrences, 27 of these bleeding episodes occurred early (within 4 months) and 17 late (mean 16.5 months). Eradication of the varices was achieved in 29 patients (60%) with a mean of 6.2 sessions and within a mean of 6 months. Of these 48 patients 2 have been lost to follow-up, 25 (52%) are alive after a mean follow-up of 29 months, and 21 (44%) died (though only 2 from variceal bleeding). The survival curve (Kaplan-Meier) of these 60 bleeders is 45% and 37% at 2 and 4 years respectively. Sclerotherapy caused no death and only minor adverse effects. These results confirm those in the literature. We advocate endoscopic sclerosis as first choice in the treatment of ruptured esophageal varices. SN - 0036-7672 UR - https://www.unboundmedicine.com/medline/citation/3266368/[Endoscopic_sclerotherapy_and_esophageal_varices]_ L2 - https://www.diseaseinfosearch.org/result/2658 DB - PRIME DP - Unbound Medicine ER -