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COVID-19: Progress in diagnostics, therapy and vaccination.
Theranostics. 2020; 10(17):7821-7835.T

Abstract

Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has recently become a pandemic. As the sudden emergence and rapid spread of SARS-CoV-2 is endangering global health and the economy, the development of strategies to contain the virus's spread are urgently needed. At present, various diagnostic kits to test for SARS-CoV-2 are available for use to initiate appropriate treatment faster and to limit further spread of the virus. Several drugs have demonstrated in vitro activity against SARS-CoV-2 or potential clinical benefits. In addition, institutions and companies worldwide are working tirelessly to develop treatments and vaccines against COVID-19. However, no drug or vaccine has yet been specifically approved for COVID-19. Given the urgency of the outbreak, we focus here on recent advances in the diagnostics, treatment, and vaccine development for SARS-CoV-2 infection, helping to guide strategies to address the current COVID-19 pandemic.

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Authors+Show Affiliations

Liu X
State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & National Institute of Diagnostics and Vaccine Development in Infectious Disease, School of Public Health, Xiamen University, 361102, China.
Liu C
State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, 361102, China.
Liu G
State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, 361102, China.
Luo W
State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & National Institute of Diagnostics and Vaccine Development in Infectious Disease, School of Public Health, Xiamen University, 361102, China.
Xia N
State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & National Institute of Diagnostics and Vaccine Development in Infectious Disease, School of Public Health, Xiamen University, 361102, China.

MeSH

Antiviral AgentsBetacoronavirusCOVID-19COVID-19 TestingCOVID-19 VaccinesClinical Laboratory TechniquesCoronavirus InfectionsDrug DevelopmentHumansImmunization, PassivePandemicsPneumonia, ViralSARS-CoV-2Theranostic NanomedicineViral VaccinesCOVID-19 Drug TreatmentCOVID-19 Serotherapy

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

32685022

Citation

Liu, Xue, et al. "COVID-19: Progress in Diagnostics, Therapy and Vaccination." Theranostics, vol. 10, no. 17, 2020, pp. 7821-7835.
Liu X, Liu C, Liu G, et al. COVID-19: Progress in diagnostics, therapy and vaccination. Theranostics. 2020;10(17):7821-7835.
Liu, X., Liu, C., Liu, G., Luo, W., & Xia, N. (2020). COVID-19: Progress in diagnostics, therapy and vaccination. Theranostics, 10(17), 7821-7835. https://doi.org/10.7150/thno.47987
Liu X, et al. COVID-19: Progress in Diagnostics, Therapy and Vaccination. Theranostics. 2020;10(17):7821-7835. PubMed PMID: 32685022.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - COVID-19: Progress in diagnostics, therapy and vaccination. AU - Liu,Xue, AU - Liu,Chao, AU - Liu,Gang, AU - Luo,Wenxin, AU - Xia,Ningshao, Y1 - 2020/06/19/ PY - 2020/05/09/received PY - 2020/06/07/accepted PY - 2020/7/21/entrez PY - 2020/7/21/pubmed PY - 2020/8/7/medline KW - COVID-19 KW - SARS-CoV-2 KW - antiviral therapy KW - diagnostics SP - 7821 EP - 7835 JF - Theranostics JO - Theranostics VL - 10 IS - 17 N2 - Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has recently become a pandemic. As the sudden emergence and rapid spread of SARS-CoV-2 is endangering global health and the economy, the development of strategies to contain the virus's spread are urgently needed. At present, various diagnostic kits to test for SARS-CoV-2 are available for use to initiate appropriate treatment faster and to limit further spread of the virus. Several drugs have demonstrated in vitro activity against SARS-CoV-2 or potential clinical benefits. In addition, institutions and companies worldwide are working tirelessly to develop treatments and vaccines against COVID-19. However, no drug or vaccine has yet been specifically approved for COVID-19. Given the urgency of the outbreak, we focus here on recent advances in the diagnostics, treatment, and vaccine development for SARS-CoV-2 infection, helping to guide strategies to address the current COVID-19 pandemic. SN - 1838-7640 UR - https://www.unboundmedicine.com/medline/citation/32685022/COVID_19:_Progress_in_diagnostics_therapy_and_vaccination_ DB - PRIME DP - Unbound Medicine ER -