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COVID-19 - Recent advancements in identifying novel vaccine candidates and current status of upcoming SARS-CoV-2 vaccines.
Hum Vaccin Immunother. 2020 12 01; 16(12):2891-2904.HV

Abstract

The COVID-19 pandemic caused by SARS-CoV-2 has spread rapidly. To date, countries have relied on the prevention of the disease through isolation, quarantine, and clinical care of affected individuals. However, studies on the roles of asymptomatic and mildly infected subjects in disease transmission, use of antiviral drugs, and vaccination of the general population will be very important for mitigating the effects of the eventual return of this pandemic. Initial investigations are ongoing to evaluate antigenic structures of SARS-CoV-2 and the immunogenicity of vaccine candidates. There also is a need to comprehensively compile the details of previous studies on SARS-related vaccines that can be extrapolated to identify potent vaccine targets for developing COVID-19 vaccines. This review aims to analyze previous studies, current status, and future possibilities for producing SARS-CoV-2 vaccines.

Authors+Show Affiliations

Division of Veterinary Clinical Complex, Faculty of Veterinary Sciences and Animal Husbandry, Sher-E-Kashmir University of Agricultural Sciences and Technology of Kashmir , Srinagar, India.Department of Biotechnology, University of Kashmir , Srinagar, India.Division of Veterinary Clinical Complex, Faculty of Veterinary Sciences and Animal Husbandry, Sher-E-Kashmir University of Agricultural Sciences and Technology of Kashmir , Srinagar, India.Division of Veterinary Clinical Complex, Faculty of Veterinary Sciences and Animal Husbandry, Sher-E-Kashmir University of Agricultural Sciences and Technology of Kashmir , Srinagar, India.Division of Veterinary Clinical Complex, Faculty of Veterinary Sciences and Animal Husbandry, Sher-E-Kashmir University of Agricultural Sciences and Technology of Kashmir , Srinagar, India.Division of Biotechnology, ICAR-Indian Veterinary Research Institute , Bareilly, India.Division of Pathology, ICAR-Indian Veterinary Research Institute , Bareilly, India.Division of Pathology, ICAR-Indian Veterinary Research Institute , Bareilly, India.Department of Veterinary Microbiology and Immunology, College of Veterinary Sciences, UP Pandit Deen Dayal Upadhayay Pashu Chikitsa Vigyan Vishwavidyalay Evum Go-Anusandhan Sansthan , Mathura, India.Division of Biological Standardization, ICAR-Indian Veterinary Research Institute , Bareilly, India.Department of Microbiology, Tribhuvan University Teaching Hospital, Institute of Medicine , Kathmandu, Nepal.Molecular Diagnostic Laboratory, Johns Hopkins Aramco Healthcare , Dhahran, Saudi Arabia.Public Health and Infection Research Group, Faculty of Health Sciences, Universidad Tecnologica de Pereira , Pereira, Colombia. Grupo de Investigacion Biomedicina, Faculty of Medicine, Fundacion Universitaria Autonoma de las Americas , Risaralda, Colombia.Division of Pathology, ICAR-Indian Veterinary Research Institute , Bareilly, India.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

32703064

Citation

Iqbal Yatoo, Mohd, et al. "COVID-19 - Recent Advancements in Identifying Novel Vaccine Candidates and Current Status of Upcoming SARS-CoV-2 Vaccines." Human Vaccines & Immunotherapeutics, vol. 16, no. 12, 2020, pp. 2891-2904.
Iqbal Yatoo M, Hamid Z, Parray OR, et al. COVID-19 - Recent advancements in identifying novel vaccine candidates and current status of upcoming SARS-CoV-2 vaccines. Hum Vaccin Immunother. 2020;16(12):2891-2904.
Iqbal Yatoo, M., Hamid, Z., Parray, O. R., Wani, A. H., Ul Haq, A., Saxena, A., Patel, S. K., Pathak, M., Tiwari, R., Malik, Y. S., Sah, R., Rabaan, A. A., Rodriguez Morales, A. J., & Dhama, K. (2020). COVID-19 - Recent advancements in identifying novel vaccine candidates and current status of upcoming SARS-CoV-2 vaccines. Human Vaccines & Immunotherapeutics, 16(12), 2891-2904. https://doi.org/10.1080/21645515.2020.1788310
Iqbal Yatoo M, et al. COVID-19 - Recent Advancements in Identifying Novel Vaccine Candidates and Current Status of Upcoming SARS-CoV-2 Vaccines. Hum Vaccin Immunother. 2020 12 1;16(12):2891-2904. PubMed PMID: 32703064.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - COVID-19 - Recent advancements in identifying novel vaccine candidates and current status of upcoming SARS-CoV-2 vaccines. AU - Iqbal Yatoo,Mohd, AU - Hamid,Zeenat, AU - Parray,Oveas Rafiq, AU - Wani,Aasim Habib, AU - Ul Haq,Abrar, AU - Saxena,Archana, AU - Patel,Shailesh Kumar, AU - Pathak,Mamta, AU - Tiwari,Ruchi, AU - Malik,Yashpal Singh, AU - Sah,Ranjit, AU - Rabaan,Ali A, AU - Rodriguez Morales,Alfonso J, AU - Dhama,Kuldeep, Y1 - 2020/07/23/ PY - 2020/7/25/pubmed PY - 2021/1/16/medline PY - 2020/7/25/entrez KW - COVID-19 KW - SARS-CoV-2 KW - pandemic KW - vaccines SP - 2891 EP - 2904 JF - Human vaccines & immunotherapeutics JO - Hum Vaccin Immunother VL - 16 IS - 12 N2 - The COVID-19 pandemic caused by SARS-CoV-2 has spread rapidly. To date, countries have relied on the prevention of the disease through isolation, quarantine, and clinical care of affected individuals. However, studies on the roles of asymptomatic and mildly infected subjects in disease transmission, use of antiviral drugs, and vaccination of the general population will be very important for mitigating the effects of the eventual return of this pandemic. Initial investigations are ongoing to evaluate antigenic structures of SARS-CoV-2 and the immunogenicity of vaccine candidates. There also is a need to comprehensively compile the details of previous studies on SARS-related vaccines that can be extrapolated to identify potent vaccine targets for developing COVID-19 vaccines. This review aims to analyze previous studies, current status, and future possibilities for producing SARS-CoV-2 vaccines. SN - 2164-554X UR - https://www.unboundmedicine.com/medline/citation/32703064/COVID_19___Recent_advancements_in_identifying_novel_vaccine_candidates_and_current_status_of_upcoming_SARS_CoV_2_vaccines_ L2 - https://www.tandfonline.com/doi/full/10.1080/21645515.2020.1788310 DB - PRIME DP - Unbound Medicine ER -