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Colorectal surgery obesity-related morbidity during COVID-19.
Surg Obes Relat Dis. 2020 09; 16(9):1372-1375.SO

Abstract

Tocilizumab, a monoclonal antiinterluekin-6 receptor antibody, has been empirically used in the treatment of cytokine release syndrome associated with severe coronavirus disease 2019 infections. The efficacy and safety of these medications for these patients is unknown. The purpose of this report was to present a case of acute large bowel perforation in a morbidly obese patient with coronavirus disease 2019 pneumonia who received empiric Tocilizumab. This case report analyzes the risks of acute large bowel perforation after using this medication empirically and discusses the appropriate management of this adverse event.

Authors+Show Affiliations

Department of General Surgery, Cleveland Clinic Florida, Weston, Florida.Department of General Surgery, Cleveland Clinic Florida, Weston, Florida.Department of Gastroenterology, Cleveland Clinic Florida, Weston, Florida.Department of General Surgery, Cleveland Clinic Florida, Weston, Florida.Department of Colorectal Surgery, Cleveland Clinic Florida, Weston, Florida.Department of General Surgery, Cleveland Clinic Florida, Weston, Florida.Department of General Surgery, Cleveland Clinic Florida, Weston, Florida.Department of Laboratory Medicine, Cleveland Clinic Florida, Weston, Florida.Department of Colorectal Surgery, Cleveland Clinic Florida, Weston, Florida. Electronic address: wexners@ccf.org.

Pub Type(s)

Case Reports
Journal Article
Video-Audio Media

Language

eng

PubMed ID

32723601

Citation

Montorfano, Lisandro, et al. "Colorectal Surgery Obesity-related Morbidity During COVID-19." Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery, vol. 16, no. 9, 2020, pp. 1372-1375.
Montorfano L, Miret R, Rahman AU, et al. Colorectal surgery obesity-related morbidity during COVID-19. Surg Obes Relat Dis. 2020;16(9):1372-1375.
Montorfano, L., Miret, R., Rahman, A. U., Alonso, M., Maron, D. J., Roy, M., Ferri, F., Bejarano, P., & Wexner, S. D. (2020). Colorectal surgery obesity-related morbidity during COVID-19. Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery, 16(9), 1372-1375. https://doi.org/10.1016/j.soard.2020.06.011
Montorfano L, et al. Colorectal Surgery Obesity-related Morbidity During COVID-19. Surg Obes Relat Dis. 2020;16(9):1372-1375. PubMed PMID: 32723601.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Colorectal surgery obesity-related morbidity during COVID-19. AU - Montorfano,Lisandro, AU - Miret,Rafael, AU - Rahman,Asad Ur, AU - Alonso,Mileydis, AU - Maron,David J, AU - Roy,Mayank, AU - Ferri,Francisco, AU - Bejarano,Pablo, AU - Wexner,Steven D, Y1 - 2020/07/09/ PY - 2020/05/28/received PY - 2020/06/05/accepted PY - 2020/7/30/pubmed PY - 2020/9/10/medline PY - 2020/7/30/entrez KW - Bowel perforation KW - COVID-19 KW - Colonic perforation KW - Corticosteroids KW - IL-6 KW - SARS-CoV-2 coronavirus KW - Tocilizumab SP - 1372 EP - 1375 JF - Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery JO - Surg Obes Relat Dis VL - 16 IS - 9 N2 - Tocilizumab, a monoclonal antiinterluekin-6 receptor antibody, has been empirically used in the treatment of cytokine release syndrome associated with severe coronavirus disease 2019 infections. The efficacy and safety of these medications for these patients is unknown. The purpose of this report was to present a case of acute large bowel perforation in a morbidly obese patient with coronavirus disease 2019 pneumonia who received empiric Tocilizumab. This case report analyzes the risks of acute large bowel perforation after using this medication empirically and discusses the appropriate management of this adverse event. SN - 1878-7533 UR - https://www.unboundmedicine.com/medline/citation/32723601/Colorectal_surgery_obesity-related_morbidity_during_COVID-19 L2 - https://linkinghub.elsevier.com/retrieve/pii/S1550-7289(20)30331-2 DB - PRIME DP - Unbound Medicine ER -