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SARS-CoV-2: characteristics and current advances in research.
Virol J. 2020 Jul 29; 17(1):117.VJ

Abstract

Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection has spread rapidly across the world and become an international public health emergency. Both SARS-CoV-2 and SARS-CoV belong to subfamily Coronavirinae in the family Coronaviridae of the order Nidovirales and they are classified as the SARS-like species while belong to different cluster. Besides, viral structure, epidemiology characteristics and pathological characteristics are also different. We present a comprehensive survey of the latest coronavirus-SARS-CoV-2-from investigating its origin and evolution alongside SARS-CoV. Meanwhile, pathogenesis, cardiovascular disease in COVID-19 patients, myocardial injury and venous thromboembolism induced by SARS-CoV-2 as well as the treatment methods are summarized in this review.

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Authors+Show Affiliations

Yang Y
State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China. Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, 510515, China.
Xiao Z
Department of clinical medicine, Zhengzhou university, 100 Science Avenue, Zhengzhou, 450001, China.
Ye K
Second Clinical Medical College, Southern Medical University, Guangzhou, 510515, China.
He X
Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, 510515, China.
Sun B
State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China.
Qin Z
Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, 510515, China.
Yu J
Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, 510515, China.
Yao J
Yang Jiang Hospital, Yangjiang, 510515, Guangdong Province, China.
Wu Q
Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, 510515, China.
Bao Z
Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, 510515, China. zhangb@smu.edu.cn.
Zhao W
Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, 510515, China. zhaowei@smu.edu.cn.

MeSH

Angiotensin-Converting Enzyme 2Antiviral AgentsAsymptomatic InfectionsBetacoronavirusCOVID-19ComorbidityCoronavirus InfectionsDisease SusceptibilityEvolution, MolecularGenome, ViralHumansImmunization, PassivePandemicsPeptidyl-Dipeptidase APneumonia, ViralReceptors, CoronavirusReceptors, VirusSevere acute respiratory syndrome-related coronavirusSARS-CoV-2Viral ProteinsCOVID-19 Drug TreatmentCOVID-19 Serotherapy

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

32727485

Citation

Yang, Yicheng, et al. "SARS-CoV-2: Characteristics and Current Advances in Research." Virology Journal, vol. 17, no. 1, 2020, p. 117.
Yang Y, Xiao Z, Ye K, et al. SARS-CoV-2: characteristics and current advances in research. Virol J. 2020;17(1):117.
Yang, Y., Xiao, Z., Ye, K., He, X., Sun, B., Qin, Z., Yu, J., Yao, J., Wu, Q., Bao, Z., & Zhao, W. (2020). SARS-CoV-2: characteristics and current advances in research. Virology Journal, 17(1), 117. https://doi.org/10.1186/s12985-020-01369-z
Yang Y, et al. SARS-CoV-2: Characteristics and Current Advances in Research. Virol J. 2020 Jul 29;17(1):117. PubMed PMID: 32727485.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - SARS-CoV-2: characteristics and current advances in research. AU - Yang,Yicheng, AU - Xiao,Zhiqiang, AU - Ye,Kaiyan, AU - He,Xiaoen, AU - Sun,Bo, AU - Qin,Zhiran, AU - Yu,Jianghai, AU - Yao,Jinxiu, AU - Wu,Qinghua, AU - Bao,Zhang, AU - Zhao,Wei, Y1 - 2020/07/29/ PY - 2020/4/6/received PY - 2020/6/23/accepted PY - 2020/7/31/entrez PY - 2020/7/31/pubmed PY - 2020/8/5/medline KW - COVID-19 KW - Cardiovascular disease KW - Cytokine storm KW - Myocardial injury KW - SARS-CoV-2 KW - Treatment KW - Venous thromboembolism SP - 117 EP - 117 JF - Virology journal JO - Virol J VL - 17 IS - 1 N2 - Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection has spread rapidly across the world and become an international public health emergency. Both SARS-CoV-2 and SARS-CoV belong to subfamily Coronavirinae in the family Coronaviridae of the order Nidovirales and they are classified as the SARS-like species while belong to different cluster. Besides, viral structure, epidemiology characteristics and pathological characteristics are also different. We present a comprehensive survey of the latest coronavirus-SARS-CoV-2-from investigating its origin and evolution alongside SARS-CoV. Meanwhile, pathogenesis, cardiovascular disease in COVID-19 patients, myocardial injury and venous thromboembolism induced by SARS-CoV-2 as well as the treatment methods are summarized in this review. SN - 1743-422X UR - https://www.unboundmedicine.com/medline/citation/32727485/SARS_CoV_2:_characteristics_and_current_advances_in_research_ DB - PRIME DP - Unbound Medicine ER -