TY - JOUR T1 - Effects of Sulfamethoxazole Exposure on the Growth, Antioxidant System of Chlorella vulgaris and Microcystis aeruginosa. AU - Dong,Xiaotong, AU - Sun,Shaohua, AU - Jia,Ruibao, AU - Xu,Lirong, AU - Hou,Wei, AU - Lu,Nannan, AU - Wang,Mingquan, AU - Zhao,Qinghua, AU - Hou,Li'an, Y1 - 2020/08/01/ PY - 2020/04/24/received PY - 2020/07/24/accepted PY - 2020/8/3/pubmed PY - 2020/9/25/medline PY - 2020/8/3/entrez KW - Antioxidant capacity KW - Growth inhibition rate KW - Lipid peroxidation KW - Sulfamethoxazole SP - 358 EP - 365 JF - Bulletin of environmental contamination and toxicology JO - Bull Environ Contam Toxicol VL - 105 IS - 3 N2 - Sulfamethoxazole (SMZ) is a kind of sulfonamides antibiotic, which is widely used in human life. This study investigated the effects of SMZ on physiological and biochemical indexes of Chlorella vulgaris (C. vulgaris) and Microcystis aeruginosa (M. aeruginosa) for 35-day. The results showed that SMZ inhibited the growth and Chl-a content of C. vulgaris and M. aeruginosa, and growth inhibition rate was 8.06%-95.86%, Chl-a content decreased 2.44%-98.04%. SMZ resulting in increased SOD and CAT activity and destroyed the dynamic balance of antioxidant system. In addition, SMZ increased the content of malondialdehyde (MDA) in algae, destroyed the cell membrane to a certain extent, which was 1.8-7.3 folds higher than the control group. High concentration of SMZ can make algae cells exceed the limit of cell antioxidant capacity. Coupled with the serious damage of cell membrane, algae cells begin to appear a large number of death phenomenon. SN - 1432-0800 UR - https://www.unboundmedicine.com/medline/citation/32740748/Effects_of_Sulfamethoxazole_Exposure_on_the_Growth_Antioxidant_System_of_Chlorella_vulgaris_and_Microcystis_aeruginosa_ DB - PRIME DP - Unbound Medicine ER -