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Age-specific SARS-CoV-2 infection fatality ratio and associated risk factors, Italy, February to April 2020.
Euro Surveill. 2020 08; 25(31)ES

Abstract

We analysed 5,484 close contacts of coronavirus disease (COVID-19) cases in Italy, all tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Infection fatality ratio was 0.43% (95% confidence interval (CI): 0.21-0.79) for individuals younger than 70 years and 10.5% (95% CI: 8.0-13.6) for older individuals. Risk of death after infection was 62% lower (95% CI: 31-80) in clusters identified after 16 March 2020 and 1.8-fold higher for males (95% CI: 1.03-3.16).

Authors+Show Affiliations

Bruno Kessler Foundation, Trento, Italy.Health Protection Agency of Pavia, Pavia, Italy. Directorate General for Health, Lombardy Region, Milan, Italy.Directorate General for Health, Lombardy Region, Milan, Italy.Bruno Kessler Foundation, Trento, Italy.Bruno Kessler Foundation, Trento, Italy.Bruno Kessler Foundation, Trento, Italy.Quality Management Unit, Papa Giovanni XXIII Hospital, Bergamo, Italy. Directorate General for Health, Lombardy Region, Milan, Italy.Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Pavia, Italy.Directorate General for Health, Lombardy Region, Milan, Italy.Department of Decision Sciences, Bocconi University, Milan, Italy. Dondena Centre for Research on Social Dynamics and Public Policy, Bocconi University, Milan, Italy.Directorate General for Health, Lombardy Region, Milan, Italy.Dipartimento di Fisiopatologia Medico-Chirurgica e dei Trapianti, Università degli Studi di Milano, Milan, Italy. Dipartimento di Anestesia, Rianimazione ed Emergenza-Urgenza, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.Department of Social and Political Sciences, Bocconi University, Milan, Italy. Dondena Centre for Research on Social Dynamics and Public Policy, Bocconi University, Milan, Italy.Directorate General for Health, Lombardy Region, Milan, Italy.Department of Epidemiology and Biostatistics, Indiana University School of Public Health, Bloomington, United States.Bruno Kessler Foundation, Trento, Italy.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32762797

Citation

Poletti, Piero, et al. "Age-specific SARS-CoV-2 Infection Fatality Ratio and Associated Risk Factors, Italy, February to April 2020." Euro Surveillance : Bulletin Europeen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin, vol. 25, no. 31, 2020.
Poletti P, Tirani M, Cereda D, et al. Age-specific SARS-CoV-2 infection fatality ratio and associated risk factors, Italy, February to April 2020. Euro Surveill. 2020;25(31).
Poletti, P., Tirani, M., Cereda, D., Trentini, F., Guzzetta, G., Marziano, V., Buoro, S., Riboli, S., Crottogini, L., Piccarreta, R., Piatti, A., Grasselli, G., Melegaro, A., Gramegna, M., Ajelli, M., & Merler, S. (2020). Age-specific SARS-CoV-2 infection fatality ratio and associated risk factors, Italy, February to April 2020. Euro Surveillance : Bulletin Europeen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin, 25(31). https://doi.org/10.2807/1560-7917.ES.2020.25.31.2001383
Poletti P, et al. Age-specific SARS-CoV-2 Infection Fatality Ratio and Associated Risk Factors, Italy, February to April 2020. Euro Surveill. 2020;25(31) PubMed PMID: 32762797.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Age-specific SARS-CoV-2 infection fatality ratio and associated risk factors, Italy, February to April 2020. AU - Poletti,Piero, AU - Tirani,Marcello, AU - Cereda,Danilo, AU - Trentini,Filippo, AU - Guzzetta,Giorgio, AU - Marziano,Valentina, AU - Buoro,Sabrina, AU - Riboli,Simona, AU - Crottogini,Lucia, AU - Piccarreta,Raffaella, AU - Piatti,Alessandra, AU - Grasselli,Giacomo, AU - Melegaro,Alessia, AU - Gramegna,Maria, AU - Ajelli,Marco, AU - Merler,Stefano, PY - 2020/8/9/entrez PY - 2020/8/9/pubmed PY - 2020/8/21/medline KW - COVID-19 KW - SARS-CoV-2 KW - comorbidities KW - infection fatality ratio KW - mortality JF - Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin JO - Euro Surveill VL - 25 IS - 31 N2 - We analysed 5,484 close contacts of coronavirus disease (COVID-19) cases in Italy, all tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Infection fatality ratio was 0.43% (95% confidence interval (CI): 0.21-0.79) for individuals younger than 70 years and 10.5% (95% CI: 8.0-13.6) for older individuals. Risk of death after infection was 62% lower (95% CI: 31-80) in clusters identified after 16 March 2020 and 1.8-fold higher for males (95% CI: 1.03-3.16). SN - 1560-7917 UR - https://www.unboundmedicine.com/medline/citation/32762797/Age_specific_SARS_CoV_2_infection_fatality_ratio_and_associated_risk_factors_Italy_February_to_April_2020_ L2 - http://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2020.25.31.2001383 DB - PRIME DP - Unbound Medicine ER -