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Coronaviruses in cats and other companion animals: Where does SARS-CoV-2/COVID-19 fit?
Vet Microbiol. 2020 Aug; 247:108777.VM

Abstract

Coronaviruses (CoVs) cause disease in a range of agricultural and companion animal species, and can be important causes of zoonotic infections. In humans, several coronaviruses circulate seasonally. Recently, a novel zoonotic CoV named SARS-CoV-2 emerged from a bat reservoir, resulting in the COVID-19 pandemic. With a focus on felines, we review here the evidence for SARS-CoV-2 infection in cats, ferrets and dogs, describe the relationship between SARS-CoV-2 and the natural coronaviruses known to infect these species, and provide a rationale for the relative susceptibility of these species to SARS-CoV-2 through comparative analysis of the ACE-2 receptor.

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Authors+Show Affiliations

Stout AE
Department of Microbiology & Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY, 14853, United States.
André NM
Department of Microbiology & Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY, 14853, United States.
Jaimes JA
Department of Microbiology & Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY, 14853, United States.
Millet JK
Université Paris-Saclay, INRAE, UVSQ, Virologie et Immunologie Moléculaires, 78352, Jouy-en-Josas, France.
Whittaker GR
Department of Microbiology & Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY, 14853, United States; Master of Public Health Program, Cornell University, Ithaca, NY, 14853, United States; Cornell Feline Health Center, Ithaca, NY, 14853, United States. Electronic address: grw7@cornell.edu.

MeSH

Angiotensin-Converting Enzyme 2AnimalsBetacoronavirusCOVID-19Cat DiseasesCatsCoronavirus InfectionsDog DiseasesDogsEvolution, MolecularFerretsHumansPandemicsPeptidyl-Dipeptidase APneumonia, ViralReceptors, CoronavirusReceptors, VirusSARS-CoV-2Zoonoses

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

32768223

Citation

Stout, Alison E., et al. "Coronaviruses in Cats and Other Companion Animals: Where Does SARS-CoV-2/COVID-19 Fit?" Veterinary Microbiology, vol. 247, 2020, p. 108777.
Stout AE, André NM, Jaimes JA, et al. Coronaviruses in cats and other companion animals: Where does SARS-CoV-2/COVID-19 fit? Vet Microbiol. 2020;247:108777.
Stout, A. E., André, N. M., Jaimes, J. A., Millet, J. K., & Whittaker, G. R. (2020). Coronaviruses in cats and other companion animals: Where does SARS-CoV-2/COVID-19 fit? Veterinary Microbiology, 247, 108777. https://doi.org/10.1016/j.vetmic.2020.108777
Stout AE, et al. Coronaviruses in Cats and Other Companion Animals: Where Does SARS-CoV-2/COVID-19 Fit. Vet Microbiol. 2020;247:108777. PubMed PMID: 32768223.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Coronaviruses in cats and other companion animals: Where does SARS-CoV-2/COVID-19 fit? AU - Stout,Alison E, AU - André,Nicole M, AU - Jaimes,Javier A, AU - Millet,Jean K, AU - Whittaker,Gary R, Y1 - 2020/06/23/ PY - 2020/05/05/received PY - 2020/06/17/revised PY - 2020/06/20/accepted PY - 2020/8/10/entrez PY - 2020/8/10/pubmed PY - 2020/8/22/medline KW - ACE-2 KW - Coronavirus KW - Feline coronavirus KW - SARS-CoV-2 SP - 108777 EP - 108777 JF - Veterinary microbiology JO - Vet Microbiol VL - 247 N2 - Coronaviruses (CoVs) cause disease in a range of agricultural and companion animal species, and can be important causes of zoonotic infections. In humans, several coronaviruses circulate seasonally. Recently, a novel zoonotic CoV named SARS-CoV-2 emerged from a bat reservoir, resulting in the COVID-19 pandemic. With a focus on felines, we review here the evidence for SARS-CoV-2 infection in cats, ferrets and dogs, describe the relationship between SARS-CoV-2 and the natural coronaviruses known to infect these species, and provide a rationale for the relative susceptibility of these species to SARS-CoV-2 through comparative analysis of the ACE-2 receptor. SN - 1873-2542 UR - https://www.unboundmedicine.com/medline/citation/32768223/Coronaviruses_in_cats_and_other_companion_animals:_Where_does_SARS_CoV_2/COVID_19_fit DB - PRIME DP - Unbound Medicine ER -