TY - JOUR T1 - Epidemiological and Clinical Profile of Pediatric Inflammatory Multisystem Syndrome - Temporally Associated with SARS-CoV-2 (PIMS-TS) in Indian Children. AU - Dhanalakshmi,K, AU - Venkataraman,Aishwarya, AU - Balasubramanian,S, AU - Madhusudan,Manoj, AU - Amperayani,Sumanth, AU - Putilibai,Sulochana, AU - Sadasivam,Kalaimaran, AU - Ramachandran,Bala, AU - Ramanan,A V, Y1 - 2020/08/06/ PY - 2020/8/10/pubmed PY - 2020/12/22/medline PY - 2020/8/10/entrez SP - 1010 EP - 1014 JF - Indian pediatrics JO - Indian Pediatr VL - 57 IS - 11 N2 - Background: We describe the demographic, clinical and labo-ratory findings along with the treatment and outcomes among children meeting the case definition of Pediatric Inflammatory Multisystem Syndrome - Temporally associated with SARS-CoV-2 (PIMS-TS). METHODS: We analyzed the clinical and laboratory findings of children who presented with PIMS-TS during an 8-week period from May 4, 2020 to July 8, 2020. RESULTS: We report 19 children with a median age of 6 year (IQR: 13 months-16 years), who met the case definition of PIMS-TS. All of them presented with fever. Multi organ involvement (79%), mucocutaneous involvement (74%), cardiovascular symptoms (63%) and gastrointestinal symptoms (42%) were the other features. Elevated levels of C-reactive protein was found in all of them and the majority of them had evidence of coagulopathy; intensive care admissions were needed in 12 (63%) and vasoactive medications were given to 6 (31.5%) children. There were no deaths. CONCLUSION: Children with PIMS-TS present with a wide range of signs and symptoms. Fewer children in this series had coronary artery abnormalities, and there was a low incidence of RT-PCR positivity with high presence of SARS-CoV-2 antibodies. SN - 0974-7559 UR - https://www.unboundmedicine.com/medline/citation/32769230/Epidemiological_and_Clinical_Profile_of_Pediatric_Inflammatory_Multisystem_Syndrome___Temporally_Associated_with_SARS_CoV_2__PIMS_TS__in_Indian_Children_ DB - PRIME DP - Unbound Medicine ER -