Tags

Type your tag names separated by a space and hit enter

Factitious hypoglycemia due to surreptitious administration of insulin. Diagnosis, treatment, and long-term follow-up.
Ann Intern Med. 1988 Feb; 108(2):252-7.AIM

Abstract

Ten patients had factitious hypoglycemia due to surreptitious insulin injections diagnosed and were followed for up to 15 years (median, 5 years; range, 2 months to 15 years). When available, demonstration of anti-insulin antibodies was the most helpful diagnostic test. Decreased plasma C-peptide levels corroborated the diagnosis. Young women (nine of ten) with knowledge of the medical profession or relatives with diabetes mellitus predominated in the sample. Five of the patients had a history of insulin-requiring diabetes mellitus. Two patients eventually committed suicide despite the best efforts at therapy. Only three of ten patients made a successful transition into productive life after the diagnosis of factitious hypoglycemia was established. Factitious hypoglycemia remains a difficult diagnosis to make, and the long-term outcome after the diagnosis is established is unpredictable. All efforts have to be made to confirm the diagnosis before the patients are approached. The confrontation is to be made by an experienced team of health care professionals who have gained the patient's confidence through an understanding but firm manner. Long-term therapy must be planned and initiated before the patient's discharge.

Authors+Show Affiliations

Diabetes Branch, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

3277509

Citation

Grunberger, G, et al. "Factitious Hypoglycemia Due to Surreptitious Administration of Insulin. Diagnosis, Treatment, and Long-term Follow-up." Annals of Internal Medicine, vol. 108, no. 2, 1988, pp. 252-7.
Grunberger G, Weiner JL, Silverman R, et al. Factitious hypoglycemia due to surreptitious administration of insulin. Diagnosis, treatment, and long-term follow-up. Ann Intern Med. 1988;108(2):252-7.
Grunberger, G., Weiner, J. L., Silverman, R., Taylor, S., & Gorden, P. (1988). Factitious hypoglycemia due to surreptitious administration of insulin. Diagnosis, treatment, and long-term follow-up. Annals of Internal Medicine, 108(2), 252-7.
Grunberger G, et al. Factitious Hypoglycemia Due to Surreptitious Administration of Insulin. Diagnosis, Treatment, and Long-term Follow-up. Ann Intern Med. 1988;108(2):252-7. PubMed PMID: 3277509.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Factitious hypoglycemia due to surreptitious administration of insulin. Diagnosis, treatment, and long-term follow-up. AU - Grunberger,G, AU - Weiner,J L, AU - Silverman,R, AU - Taylor,S, AU - Gorden,P, PY - 1988/2/1/pubmed PY - 1988/2/1/medline PY - 1988/2/1/entrez SP - 252 EP - 7 JF - Annals of internal medicine JO - Ann Intern Med VL - 108 IS - 2 N2 - Ten patients had factitious hypoglycemia due to surreptitious insulin injections diagnosed and were followed for up to 15 years (median, 5 years; range, 2 months to 15 years). When available, demonstration of anti-insulin antibodies was the most helpful diagnostic test. Decreased plasma C-peptide levels corroborated the diagnosis. Young women (nine of ten) with knowledge of the medical profession or relatives with diabetes mellitus predominated in the sample. Five of the patients had a history of insulin-requiring diabetes mellitus. Two patients eventually committed suicide despite the best efforts at therapy. Only three of ten patients made a successful transition into productive life after the diagnosis of factitious hypoglycemia was established. Factitious hypoglycemia remains a difficult diagnosis to make, and the long-term outcome after the diagnosis is established is unpredictable. All efforts have to be made to confirm the diagnosis before the patients are approached. The confrontation is to be made by an experienced team of health care professionals who have gained the patient's confidence through an understanding but firm manner. Long-term therapy must be planned and initiated before the patient's discharge. SN - 0003-4819 UR - https://www.unboundmedicine.com/medline/citation/3277509/Factitious_hypoglycemia_due_to_surreptitious_administration_of_insulin__Diagnosis_treatment_and_long_term_follow_up_ L2 - https://www.acpjournals.org/doi/10.7326/0003-4819-108-2-252?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -