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Potential strategies for combating COVID-19.
Arch Virol. 2020 Nov; 165(11):2419-2438.AV

Abstract

Coronavirus disease 2019, also known as COVID-19, is caused by a novel coronavirus named severe acute respiratory syndrome coronavirus 2, or SARS-CoV-2. The infection has now catapulted into a full-blown pandemic across the world, which has affected more than 2 million people and has led to approximately 150,000 fatalities all over the world (WHO). In this review, we elaborate all currently available data that shed light on possible methods for treatment of COVID-19, such as antiviral drugs, corticosteroids, convalescent plasma, and potentially effective vaccines. Additionally, ongoing and discontinued clinical trials that have been carried out for validating probable treatments for COVID-19 are discussed. The review also elaborates the prospective approach and the possible advantages of using convalescent plasma and stem cells for the improvement of clinical symptoms and meeting the demand for an instantaneous cure.

Authors+Show Affiliations

Institute of Molecular Biology and Biotechnology, The University of Lahore, Lahore, Pakistan.Institute of Molecular Biology and Biotechnology, The University of Lahore, Lahore, Pakistan.Department of Clinical Sciences, College of Pharmacy, Al-Ain University of Science and Technology, Abu Dhabi, United Arab Emirates.Institute of Molecular Biology and Biotechnology, The University of Lahore, Lahore, Pakistan.Department of Pharmacy, COMSATS University Islamabad, Lahore Campus, Islamabad, 54000, Pakistan. gmdogar356@gmail.com.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

32778950

Citation

Shamim, Saba, et al. "Potential Strategies for Combating COVID-19." Archives of Virology, vol. 165, no. 11, 2020, pp. 2419-2438.
Shamim S, Khan M, Kharaba ZJ, et al. Potential strategies for combating COVID-19. Arch Virol. 2020;165(11):2419-2438.
Shamim, S., Khan, M., Kharaba, Z. J., Ijaz, M., & Murtaza, G. (2020). Potential strategies for combating COVID-19. Archives of Virology, 165(11), 2419-2438. https://doi.org/10.1007/s00705-020-04768-3
Shamim S, et al. Potential Strategies for Combating COVID-19. Arch Virol. 2020;165(11):2419-2438. PubMed PMID: 32778950.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Potential strategies for combating COVID-19. AU - Shamim,Saba, AU - Khan,Maryam, AU - Kharaba,Zelal Jaber, AU - Ijaz,Munazza, AU - Murtaza,Ghulam, Y1 - 2020/08/10/ PY - 2020/04/15/received PY - 2020/06/18/accepted PY - 2020/8/12/pubmed PY - 2020/10/22/medline PY - 2020/8/12/entrez SP - 2419 EP - 2438 JF - Archives of virology JO - Arch Virol VL - 165 IS - 11 N2 - Coronavirus disease 2019, also known as COVID-19, is caused by a novel coronavirus named severe acute respiratory syndrome coronavirus 2, or SARS-CoV-2. The infection has now catapulted into a full-blown pandemic across the world, which has affected more than 2 million people and has led to approximately 150,000 fatalities all over the world (WHO). In this review, we elaborate all currently available data that shed light on possible methods for treatment of COVID-19, such as antiviral drugs, corticosteroids, convalescent plasma, and potentially effective vaccines. Additionally, ongoing and discontinued clinical trials that have been carried out for validating probable treatments for COVID-19 are discussed. The review also elaborates the prospective approach and the possible advantages of using convalescent plasma and stem cells for the improvement of clinical symptoms and meeting the demand for an instantaneous cure. SN - 1432-8798 UR - https://www.unboundmedicine.com/medline/citation/32778950/Potential_strategies_for_combating_COVID_19_ L2 - https://dx.doi.org/10.1007/s00705-020-04768-3 DB - PRIME DP - Unbound Medicine ER -