Tags

Type your tag names separated by a space and hit enter

A Patient with Bilateral Conjunctivitis Positive for Sars-Cov-2 RNA in Conjunctival Sample.
Cornea. 2020 Jul 02 [Online ahead of print]C

Abstract

PURPOSE

To present a patient with bilateral conjunctivitis testing positive for viral RNA of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in both nasopharyngeal and conjunctival samples.

METHODS

A 40-year-old man with bilateral acute conjunctivitis and no suspicious signs of coronavirus disease 2019 (COVID-19) presented to the hospital. A detailed ophthalmic examination was performed. Samples obtained from conjunctival and nasopharyngeal swabs were tested by reverse transcription PCR (RT-PCR) for detection of SARS-CoV-2 virus. Ocular findings and duration of the presence of viral RNA in the conjunctival specimens were evaluated at follow-up visits.

RESULTS

Slit-lamp biomicroscopy revealed bilateral acute follicular conjunctivitis. The RT-PCR assay demonstrated the presence of viral RNA in the nasopharyngeal and conjunctival specimens at the initial visit and at the 4-day follow up. Conjunctivitis findings were decreased after 4 days and recovered completely without any sequelae within10 days. The PCR results of both nasopharyngeal and conjunctiva specimens were negative for the viral RNA at 10 days.

CONCLUSIONS

Bilateral conjunctivitis is rare in patients infected with COVID-19. Although it is difficult to detect viral RNA from conjunctival swabs, conjunctival secretions may be a source of contamination and protective measures must be taken.

Authors+Show Affiliations

1 Health Science University , Kayseri City Hospital, Department of Ophthalmology, Kayseri, Turkey 2 Hendek State Hospital, Department of Ophthalmology, Sakarya, Turkey 3 Health Science University, Kayseri City Hospital, Department of Internal Medicine, Kayseri, Turkey.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32794685

Citation

Sirakaya, Ender, et al. "A Patient With Bilateral Conjunctivitis Positive for Sars-Cov-2 RNA in Conjunctival Sample." Cornea, 2020.
Sirakaya E, Sahiner M, Sirakaya HA. A Patient with Bilateral Conjunctivitis Positive for Sars-Cov-2 RNA in Conjunctival Sample. Cornea. 2020.
Sirakaya, E., Sahiner, M., & Sirakaya, H. A. (2020). A Patient with Bilateral Conjunctivitis Positive for Sars-Cov-2 RNA in Conjunctival Sample. Cornea. https://doi.org/10.1097/ICO.0000000000002485
Sirakaya E, Sahiner M, Sirakaya HA. A Patient With Bilateral Conjunctivitis Positive for Sars-Cov-2 RNA in Conjunctival Sample. Cornea. 2020 Jul 2; PubMed PMID: 32794685.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A Patient with Bilateral Conjunctivitis Positive for Sars-Cov-2 RNA in Conjunctival Sample. AU - Sirakaya,Ender, AU - Sahiner,Mustafa, AU - Sirakaya,Hatice Aslan, Y1 - 2020/07/02/ PY - 2020/8/15/entrez PY - 2020/8/15/pubmed PY - 2020/8/15/medline JF - Cornea JO - Cornea N2 - PURPOSE: To present a patient with bilateral conjunctivitis testing positive for viral RNA of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in both nasopharyngeal and conjunctival samples. METHODS: A 40-year-old man with bilateral acute conjunctivitis and no suspicious signs of coronavirus disease 2019 (COVID-19) presented to the hospital. A detailed ophthalmic examination was performed. Samples obtained from conjunctival and nasopharyngeal swabs were tested by reverse transcription PCR (RT-PCR) for detection of SARS-CoV-2 virus. Ocular findings and duration of the presence of viral RNA in the conjunctival specimens were evaluated at follow-up visits. RESULTS: Slit-lamp biomicroscopy revealed bilateral acute follicular conjunctivitis. The RT-PCR assay demonstrated the presence of viral RNA in the nasopharyngeal and conjunctival specimens at the initial visit and at the 4-day follow up. Conjunctivitis findings were decreased after 4 days and recovered completely without any sequelae within10 days. The PCR results of both nasopharyngeal and conjunctiva specimens were negative for the viral RNA at 10 days. CONCLUSIONS: Bilateral conjunctivitis is rare in patients infected with COVID-19. Although it is difficult to detect viral RNA from conjunctival swabs, conjunctival secretions may be a source of contamination and protective measures must be taken. SN - 1536-4798 UR - https://www.unboundmedicine.com/medline/citation/32794685/A_Patient_with_Bilateral_Conjunctivitis_Positive_for_Sars_Cov_2_RNA_in_Conjunctival_Sample_ L2 - https://doi.org/10.1097/ICO.0000000000002485 DB - PRIME DP - Unbound Medicine ER -
Try the Free App:
Prime PubMed app for iOS iPhone iPad
Prime PubMed app for Android
Prime PubMed is provided
free to individuals by:
Unbound Medicine.