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Clinical characteristics and risk factors for mortality of patients with COVID-19 in a large data set from Mexico.
Ann Epidemiol. 2020 12; 52:93-98.e2.AE

Abstract

PURPOSE

The purpose of this study was to assess clinical characteristics and risk factors for mortality of patients with coronavirus disease 2019 (COVID-19) from Mexico, given that it currently is in active community transmission.

METHODS

Multivariate logistic regression model and Kaplan-Meier survival curves were fitted to study odds of death of characteristics and comorbidities in patients with COVID-19 in Mexico.

RESULTS

Age, sex, and the most frequent comorbidities diabetes, obesity, and hypertension were significantly associated to the risk of death by COVID-19 (P < .0001). Smoking habit was not identified as a risk factor for death. Less-frequent comorbidities such as chronic obstructive pulmonary disease, chronic kidney disease, and patients with immunosuppressed conditions also showed a significant risk for death (P < .0001). Hospitalized patients and those with pneumonia had serious risks for mortality (P < .0001), and more attention to specific conditions might be considered during clinical admission.

CONCLUSIONS

A more vulnerable positive patient is depicted by a male patient, older than 41 years, which increases their risk with more prevalent comorbidities such as diabetes, hypertension, and obesity. Some implications on outcomes are discussed.

Authors+Show Affiliations

Centro de Biotecnología Genómica-Instituto Politécnico Nacional, Reynosa, Mexico. Electronic address: gparra@ipn.mx.School of Agriculture, Massey University, Palmerston North, New Zealand.Cardiology Clinical Care, Centro Médico Pensiones, Mérida, Mexico.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32798701

Citation

Parra-Bracamonte, Gaspar Manuel, et al. "Clinical Characteristics and Risk Factors for Mortality of Patients With COVID-19 in a Large Data Set From Mexico." Annals of Epidemiology, vol. 52, 2020, pp. 93-98.e2.
Parra-Bracamonte GM, Lopez-Villalobos N, Parra-Bracamonte FE. Clinical characteristics and risk factors for mortality of patients with COVID-19 in a large data set from Mexico. Ann Epidemiol. 2020;52:93-98.e2.
Parra-Bracamonte, G. M., Lopez-Villalobos, N., & Parra-Bracamonte, F. E. (2020). Clinical characteristics and risk factors for mortality of patients with COVID-19 in a large data set from Mexico. Annals of Epidemiology, 52, 93-e2. https://doi.org/10.1016/j.annepidem.2020.08.005
Parra-Bracamonte GM, Lopez-Villalobos N, Parra-Bracamonte FE. Clinical Characteristics and Risk Factors for Mortality of Patients With COVID-19 in a Large Data Set From Mexico. Ann Epidemiol. 2020;52:93-98.e2. PubMed PMID: 32798701.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clinical characteristics and risk factors for mortality of patients with COVID-19 in a large data set from Mexico. AU - Parra-Bracamonte,Gaspar Manuel, AU - Lopez-Villalobos,Nicolas, AU - Parra-Bracamonte,Francisco E, Y1 - 2020/08/14/ PY - 2020/06/18/received PY - 2020/07/19/revised PY - 2020/08/10/accepted PY - 2020/8/18/pubmed PY - 2020/12/16/medline PY - 2020/8/18/entrez KW - Comorbidity KW - Mexico KW - Odds ratio KW - SARS-CoV-2 KW - Survival probability SP - 93 EP - 98.e2 JF - Annals of epidemiology JO - Ann Epidemiol VL - 52 N2 - PURPOSE: The purpose of this study was to assess clinical characteristics and risk factors for mortality of patients with coronavirus disease 2019 (COVID-19) from Mexico, given that it currently is in active community transmission. METHODS: Multivariate logistic regression model and Kaplan-Meier survival curves were fitted to study odds of death of characteristics and comorbidities in patients with COVID-19 in Mexico. RESULTS: Age, sex, and the most frequent comorbidities diabetes, obesity, and hypertension were significantly associated to the risk of death by COVID-19 (P < .0001). Smoking habit was not identified as a risk factor for death. Less-frequent comorbidities such as chronic obstructive pulmonary disease, chronic kidney disease, and patients with immunosuppressed conditions also showed a significant risk for death (P < .0001). Hospitalized patients and those with pneumonia had serious risks for mortality (P < .0001), and more attention to specific conditions might be considered during clinical admission. CONCLUSIONS: A more vulnerable positive patient is depicted by a male patient, older than 41 years, which increases their risk with more prevalent comorbidities such as diabetes, hypertension, and obesity. Some implications on outcomes are discussed. SN - 1873-2585 UR - https://www.unboundmedicine.com/medline/citation/32798701/Clinical_characteristics_and_risk_factors_for_mortality_of_patients_with_COVID_19_in_a_large_data_set_from_Mexico_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1047-2797(20)30286-6 DB - PRIME DP - Unbound Medicine ER -