Tags

Type your tag names separated by a space and hit enter

Asbestos exposure and laryngeal cancer: an analysis of the epidemiologic evidence.
J Occup Med. 1988 Jan; 30(1):23-7.JO

Abstract

We conducted a critical analysis of the available epidemiologic investigations on the causal relationship between asbestos exposure and laryngeal cancer. A review of nine case-control studies indicates that the estimated risk (odds ratio) attributable to asbestos exposure alone is negligible when smoking and ethanol intake are appropriately controlled for. Six of the 12 cohort studies demonstrated no significant increase in the standardized mortality ratio due to asbestos exposure. The remaining six longitudinal studies showed an increased standardized mortality ratio from 1.91 to 5.41 but no adjustment was made for the confounding effects of smoking and ethanol consumption. In conclusion, the available epidemiologic evidence does not support a causal association between asbestos exposure and laryngeal cancer.

Authors+Show Affiliations

Department of Medicine, Yale University School of Medicine, New Haven, CT 06510.No affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

3280756

Citation

Chan, C K., and J B. Gee. "Asbestos Exposure and Laryngeal Cancer: an Analysis of the Epidemiologic Evidence." Journal of Occupational Medicine. : Official Publication of the Industrial Medical Association, vol. 30, no. 1, 1988, pp. 23-7.
Chan CK, Gee JB. Asbestos exposure and laryngeal cancer: an analysis of the epidemiologic evidence. J Occup Med. 1988;30(1):23-7.
Chan, C. K., & Gee, J. B. (1988). Asbestos exposure and laryngeal cancer: an analysis of the epidemiologic evidence. Journal of Occupational Medicine. : Official Publication of the Industrial Medical Association, 30(1), 23-7.
Chan CK, Gee JB. Asbestos Exposure and Laryngeal Cancer: an Analysis of the Epidemiologic Evidence. J Occup Med. 1988;30(1):23-7. PubMed PMID: 3280756.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Asbestos exposure and laryngeal cancer: an analysis of the epidemiologic evidence. AU - Chan,C K, AU - Gee,J B, PY - 1988/1/1/pubmed PY - 1988/1/1/medline PY - 1988/1/1/entrez SP - 23 EP - 7 JF - Journal of occupational medicine. : official publication of the Industrial Medical Association JO - J Occup Med VL - 30 IS - 1 N2 - We conducted a critical analysis of the available epidemiologic investigations on the causal relationship between asbestos exposure and laryngeal cancer. A review of nine case-control studies indicates that the estimated risk (odds ratio) attributable to asbestos exposure alone is negligible when smoking and ethanol intake are appropriately controlled for. Six of the 12 cohort studies demonstrated no significant increase in the standardized mortality ratio due to asbestos exposure. The remaining six longitudinal studies showed an increased standardized mortality ratio from 1.91 to 5.41 but no adjustment was made for the confounding effects of smoking and ethanol consumption. In conclusion, the available epidemiologic evidence does not support a causal association between asbestos exposure and laryngeal cancer. SN - 0096-1736 UR - https://www.unboundmedicine.com/medline/citation/3280756/Asbestos_exposure_and_laryngeal_cancer:_an_analysis_of_the_epidemiologic_evidence_ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=linkout&SEARCH=3280756.ui DB - PRIME DP - Unbound Medicine ER -