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The Effect of Voluntary Exercise on Gut Microbiota in Partially Hydrolyzed Guar Gum Intake Mice under High-Fat Diet Feeding.
Nutrients. 2020 Aug 19; 12(9)N

Abstract

Although dietary fiber treatment alters the gut microbiota and its metabolite production, it is unclear whether or not exercise habits can have a supplemental effect on changes in gut microbiota in dietary fiber-treated mice. To clarify the supplemental effect of voluntary exercise on gut microbiota in partially hydrolyzed guar gum (PHGG), which is a soluble dietary fiber, treated mice under high-fat diet (HFD) feeding, 4-week-old male C57BL/6J mice (n = 80) were randomly divided into two dietary groups: the control-diet (CD) and HFD. Then, each dietary group was treated with or without PHGG, and with or without wheel running. After the experimental period, measurement of maximal oxygen consumption, a glucose tolerance test and fecal materials collection for analysis of gut microbiota were carried out. Voluntary exercise load in PHGG treatment under HFD feeding showed the supplemental effect of exercise on obesity (p < 0.01) and glucose tolerance (p < 0.01). Additionally, in both CD and HFD groups, voluntary exercise accelerated the decrease in the Firmicutes/Bacteroidetes ratio in mice fed with PHGG (p < 0.01). These findings suggest that voluntary exercise might activate the prevention of obesity and insulin resistance more via change in gut microbiota in mice administrated with PHGG.

Authors+Show Affiliations

Graduate School of Health Science and Technology, Kawasaki University of Medical Welfare, Kurashiki, Okayama 701-0193, Japan. Department of Clinical Nutrition, Kawasaki University of Medical Welfare, Kurashiki, Okayama 701-0193, Japan.Department of Health and Sports Science, Kawasaki University of Medical Welfare, Kurashiki, Okayama 701-0193, Japan.Graduate School of Health Science and Technology, Kawasaki University of Medical Welfare, Kurashiki, Okayama 701-0193, Japan.Department of Health and Sports Science, Kawasaki University of Medical Welfare, Kurashiki, Okayama 701-0193, Japan.Graduate School of Health Science and Technology, Kawasaki University of Medical Welfare, Kurashiki, Okayama 701-0193, Japan.Graduate School of Health Science and Technology, Kawasaki University of Medical Welfare, Kurashiki, Okayama 701-0193, Japan.Department of Human Health, University of Marketing and Distribution Sciences, Kobe, Hyogo 651-2103, Japan.Graduate School of Health Science and Technology, Kawasaki University of Medical Welfare, Kurashiki, Okayama 701-0193, Japan. Department of Clinical Nutrition, Kawasaki University of Medical Welfare, Kurashiki, Okayama 701-0193, Japan.Department of Health and Sports Science, Kawasaki University of Medical Welfare, Kurashiki, Okayama 701-0193, Japan.Graduate School of Health Science and Technology, Kawasaki University of Medical Welfare, Kurashiki, Okayama 701-0193, Japan. Department of Health and Sports Science, Kawasaki University of Medical Welfare, Kurashiki, Okayama 701-0193, Japan.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32825157

Citation

Aoki, Takafumi, et al. "The Effect of Voluntary Exercise On Gut Microbiota in Partially Hydrolyzed Guar Gum Intake Mice Under High-Fat Diet Feeding." Nutrients, vol. 12, no. 9, 2020.
Aoki T, Oyanagi E, Watanabe C, et al. The Effect of Voluntary Exercise on Gut Microbiota in Partially Hydrolyzed Guar Gum Intake Mice under High-Fat Diet Feeding. Nutrients. 2020;12(9).
Aoki, T., Oyanagi, E., Watanabe, C., Kobiki, N., Miura, S., Yokogawa, Y., Kitamura, H., Teramoto, F., Kremenik, M. J., & Yano, H. (2020). The Effect of Voluntary Exercise on Gut Microbiota in Partially Hydrolyzed Guar Gum Intake Mice under High-Fat Diet Feeding. Nutrients, 12(9). https://doi.org/10.3390/nu12092508
Aoki T, et al. The Effect of Voluntary Exercise On Gut Microbiota in Partially Hydrolyzed Guar Gum Intake Mice Under High-Fat Diet Feeding. Nutrients. 2020 Aug 19;12(9) PubMed PMID: 32825157.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The Effect of Voluntary Exercise on Gut Microbiota in Partially Hydrolyzed Guar Gum Intake Mice under High-Fat Diet Feeding. AU - Aoki,Takafumi, AU - Oyanagi,Eri, AU - Watanabe,Chihiro, AU - Kobiki,Nanako, AU - Miura,Suzuka, AU - Yokogawa,Yuka, AU - Kitamura,Hiromi, AU - Teramoto,Fusako, AU - Kremenik,Michael J, AU - Yano,Hiromi, Y1 - 2020/08/19/ PY - 2020/07/16/received PY - 2020/08/05/revised PY - 2020/08/17/accepted PY - 2020/8/23/entrez PY - 2020/8/23/pubmed PY - 2021/3/30/medline KW - F/B ratio KW - dietary fiber KW - wheel running JF - Nutrients JO - Nutrients VL - 12 IS - 9 N2 - Although dietary fiber treatment alters the gut microbiota and its metabolite production, it is unclear whether or not exercise habits can have a supplemental effect on changes in gut microbiota in dietary fiber-treated mice. To clarify the supplemental effect of voluntary exercise on gut microbiota in partially hydrolyzed guar gum (PHGG), which is a soluble dietary fiber, treated mice under high-fat diet (HFD) feeding, 4-week-old male C57BL/6J mice (n = 80) were randomly divided into two dietary groups: the control-diet (CD) and HFD. Then, each dietary group was treated with or without PHGG, and with or without wheel running. After the experimental period, measurement of maximal oxygen consumption, a glucose tolerance test and fecal materials collection for analysis of gut microbiota were carried out. Voluntary exercise load in PHGG treatment under HFD feeding showed the supplemental effect of exercise on obesity (p < 0.01) and glucose tolerance (p < 0.01). Additionally, in both CD and HFD groups, voluntary exercise accelerated the decrease in the Firmicutes/Bacteroidetes ratio in mice fed with PHGG (p < 0.01). These findings suggest that voluntary exercise might activate the prevention of obesity and insulin resistance more via change in gut microbiota in mice administrated with PHGG. SN - 2072-6643 UR - https://www.unboundmedicine.com/medline/citation/32825157/The_Effect_of_Voluntary_Exercise_on_Gut_Microbiota_in_Partially_Hydrolyzed_Guar_Gum_Intake_Mice_under_High_Fat_Diet_Feeding_ L2 - https://www.mdpi.com/resolver?pii=nu12092508 DB - PRIME DP - Unbound Medicine ER -