TY - JOUR T1 - Treatment Armamentarium of COVID-19: Evolving Strategies and Evidence So Far. AU - Dhampalwar,Swapnil, AU - Saigal,Sanjiv, AU - Soin,Arvinder S, Y1 - 2020/07/16/ PY - 2020/05/11/received PY - 2020/07/05/accepted PY - 2020/8/25/pubmed PY - 2020/8/25/medline PY - 2020/8/25/entrez KW - ARDS, Acute Respiratory Distress Syndrome KW - COVID-19 KW - COVID-19 treatment KW - COVID-19, COrona VIrus Disease - 2019 KW - CQ, Chloroquine KW - HCQ, Hydroxychloroquine KW - IL-6, Interleukin-6 KW - INF, Interferon KW - LPV/TRV, Lopinavir/ritonavir KW - SARS-CoV-2 KW - SARS-CoV-2, Severe Acute Respiratory Syndrome Coronavirus 2 KW - TCZ, Tocilizumab KW - WHO, World Health Organization KW - coronavirus disease KW - novel coronavirus SP - 599 EP - 609 JF - Journal of clinical and experimental hepatology JO - J Clin Exp Hepatol VL - 10 IS - 6 N2 - The outbreak of SARS-CoV-2 started in Hubei province of China in December 2019 and rapidly spread all over the world. It has infected more than 7 million people worldwide and has pushed half of the world in a state of lockdown. There is an urgent unmet need of interventions both for prevention and treatment of this disease and more than 500 clinical trials are ongoing in this regard. At present, no study with robust methodology have clearly demonstrated benefits of hydroxychloroquine for treatment, preexposure prophylaxis in healthcare workers or post exposure prophylaxis in COrona VIrus Disease-2019. Remdesivir has been shown to have modest benefits in moderate to severe disease, if administered early. Given the rapid pace of clinical information and discoveries, it is important for clinicians to be up to date with the latest, evidence-based treatment options available for this novel disease. Keeping up with this current pace of information, we review the clinical studies of different therapeutic options available to treat SARS-CoV-2. SN - 0973-6883 UR - https://www.unboundmedicine.com/medline/citation/32837097/Treatment_Armamentarium_of_COVID_19:_Evolving_Strategies_and_Evidence_So_Far_ DB - PRIME DP - Unbound Medicine ER -