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Epidemiology of alcoholic liver disease.
Semin Liver Dis. 1988 Feb; 8(1):12-25.SL

Abstract

Although there exists a relationship between alcohol consumption and alcoholic liver disease at both the aggregate and individual levels, it is also well established that less than one-third of alcoholics or heavy drinkers develop serious alcohol-related liver damage. A number of factors have been proposed to account for this susceptibility. Evidence supporting the direct dose-response relationship and the role of genetic and environmental factors in influencing vulnerability are reviewed. To date, no consistent evidence attests to the significance of any one factor in the susceptibility to developing alcoholic liver disease.

Authors+Show Affiliations

Division of Biometry and Epidemiology, National Institute on Alcohol Abuse and Alcoholism, Rockville, Maryland 20857.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

3283941

Citation

Grant, B F., et al. "Epidemiology of Alcoholic Liver Disease." Seminars in Liver Disease, vol. 8, no. 1, 1988, pp. 12-25.
Grant BF, Dufour MC, Harford TC. Epidemiology of alcoholic liver disease. Semin Liver Dis. 1988;8(1):12-25.
Grant, B. F., Dufour, M. C., & Harford, T. C. (1988). Epidemiology of alcoholic liver disease. Seminars in Liver Disease, 8(1), 12-25.
Grant BF, Dufour MC, Harford TC. Epidemiology of Alcoholic Liver Disease. Semin Liver Dis. 1988;8(1):12-25. PubMed PMID: 3283941.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Epidemiology of alcoholic liver disease. AU - Grant,B F, AU - Dufour,M C, AU - Harford,T C, PY - 1988/2/1/pubmed PY - 1988/2/1/medline PY - 1988/2/1/entrez SP - 12 EP - 25 JF - Seminars in liver disease JO - Semin Liver Dis VL - 8 IS - 1 N2 - Although there exists a relationship between alcohol consumption and alcoholic liver disease at both the aggregate and individual levels, it is also well established that less than one-third of alcoholics or heavy drinkers develop serious alcohol-related liver damage. A number of factors have been proposed to account for this susceptibility. Evidence supporting the direct dose-response relationship and the role of genetic and environmental factors in influencing vulnerability are reviewed. To date, no consistent evidence attests to the significance of any one factor in the susceptibility to developing alcoholic liver disease. SN - 0272-8087 UR - https://www.unboundmedicine.com/medline/citation/3283941/Epidemiology_of_alcoholic_liver_disease_ L2 - https://www.thieme-connect.com/DOI/DOI?10.1055/s-2008-1040525 DB - PRIME DP - Unbound Medicine ER -