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Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), a newly emerged pathogen: an overview.
Pathog Dis. 2020 08 01; 78(6)PD

Abstract

Coronavirus disease 2019 (COVID-19) is a viral pneumonia, responsible for the recent pandemic, and originated from Wuhan, China, in December 2019. The causative agent of the outbreak was identified as coronavirus and designated as severe acute respiratory syndrome coronavirus 2 (SARS- CoV-2). Few years back, the severe acute respiratory syndrome coronavirus (SARS- CoV) and the Middle East respiratory syndrome coronavirus (MERS-CoV) were reported to be highly pathogenic and caused severe infections in humans. In the current situation SARS-CoV-2 has become the third highly pathogenic coronavirus that is responsible for the present outbreak in human population. At the time of this review, there were more than 14 007 791 confirmed COVID-19 patients which associated with over 597 105 deaths in more then 216 countries across the globe (as reported by World Health Organization). In this review we have discussed about SARS-CoV, MERS-CoV and SARC-CoV-2, their reservoirs, role of spike proteins and immunogenicity. We have also covered the diagnosis, therapeutics and vaccine status of SARS-CoV-2.

Authors+Show Affiliations

School of Biotechnology, Gautam Buddha University, Yamuna Expressway, Greater Noida, Uttar Pradesh 210312, India.Department of Zoology, Gargi College, University of Delhi, New Delhi, Delhi 110049 India.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

32840560

Citation

Rathore, Jitendra Singh, and Chaitali Ghosh. "Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), a Newly Emerged Pathogen: an Overview." Pathogens and Disease, vol. 78, no. 6, 2020.
Rathore JS, Ghosh C. Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), a newly emerged pathogen: an overview. Pathog Dis. 2020;78(6).
Rathore, J. S., & Ghosh, C. (2020). Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), a newly emerged pathogen: an overview. Pathogens and Disease, 78(6). https://doi.org/10.1093/femspd/ftaa042
Rathore JS, Ghosh C. Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), a Newly Emerged Pathogen: an Overview. Pathog Dis. 2020 08 1;78(6) PubMed PMID: 32840560.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), a newly emerged pathogen: an overview. AU - Rathore,Jitendra Singh, AU - Ghosh,Chaitali, PY - 2020/05/18/received PY - 2020/08/07/accepted PY - 2020/8/26/pubmed PY - 2020/9/17/medline PY - 2020/8/26/entrez KW - COVID 19 KW - MERS-CoV KW - SARS-CoV KW - SARS-CoV-2 KW - spike protein and therapeutics JF - Pathogens and disease JO - Pathog Dis VL - 78 IS - 6 N2 - Coronavirus disease 2019 (COVID-19) is a viral pneumonia, responsible for the recent pandemic, and originated from Wuhan, China, in December 2019. The causative agent of the outbreak was identified as coronavirus and designated as severe acute respiratory syndrome coronavirus 2 (SARS- CoV-2). Few years back, the severe acute respiratory syndrome coronavirus (SARS- CoV) and the Middle East respiratory syndrome coronavirus (MERS-CoV) were reported to be highly pathogenic and caused severe infections in humans. In the current situation SARS-CoV-2 has become the third highly pathogenic coronavirus that is responsible for the present outbreak in human population. At the time of this review, there were more than 14 007 791 confirmed COVID-19 patients which associated with over 597 105 deaths in more then 216 countries across the globe (as reported by World Health Organization). In this review we have discussed about SARS-CoV, MERS-CoV and SARC-CoV-2, their reservoirs, role of spike proteins and immunogenicity. We have also covered the diagnosis, therapeutics and vaccine status of SARS-CoV-2. SN - 2049-632X UR - https://www.unboundmedicine.com/medline/citation/32840560/Severe_acute_respiratory_syndrome_coronavirus_2__SARS_CoV_2__a_newly_emerged_pathogen:_an_overview_ L2 - https://academic.oup.com/femspd/article-lookup/doi/10.1093/femspd/ftaa042 DB - PRIME DP - Unbound Medicine ER -