Tags

Type your tag names separated by a space and hit enter

Neurological complications of coronavirus infection; a comparative review and lessons learned during the COVID-19 pandemic.
J Neurol Sci. 2020 10 15; 417:117085.JN

Abstract

INTRODUCTION

Coronavirus disease-19 (COVID-19) pandemic continues to grow all over the world. Several studies have been performed, focusing on understanding the acute respiratory syndrome and treatment strategies. However, there is growing evidence indicating neurological manifestations occur in patients with COVID-19. Similarly, the other coronaviruses (CoV) epidemics; severe acute respiratory syndrome (SARS-CoV-1) and Middle East respiratory syndrome (MERS-CoV) have been associated with neurological complications.

METHODS

This systematic review serves to summarize available information regarding the potential effects of different types of CoV on the nervous system and describes the range of clinical neurological complications that have been reported thus far in COVID-19.

RESULTS

Two hundred and twenty-five studies on CoV infections associated neurological manifestations in human were reviewed. Of those, 208 articles were pertinent to COVID-19. The most common neurological complaints in COVID-19 were anosmia, ageusia, and headache, but more serious complications, such as stroke, impairment of consciousness, seizures, and encephalopathy, have also been reported.

CONCLUSION

There are several similarities between neurological complications after SARS-CoV-1, MERS-CoV and COVID-19, however, the scope of the epidemics and number of patients are very different. Reports on the neurological complications after and during COVID-19 are growing on a daily basis. Accordingly, comprehensive knowledge of these complications will help health care providers to be attentive to these complications and diagnose and treat them timely.

Authors+Show Affiliations

Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada; Clinical Neurology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada; Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China.Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.Department of Neurological Surgery, Keck School of Medicine, University of Southern California (USC), Los Angeles, CA, USA. Electronic address: mowla@usc.edu.

Pub Type(s)

Comparative Study
Journal Article
Review

Language

eng

PubMed ID

32871412

Citation

Sharifian-Dorche, Maryam, et al. "Neurological Complications of Coronavirus Infection; a Comparative Review and Lessons Learned During the COVID-19 Pandemic." Journal of the Neurological Sciences, vol. 417, 2020, p. 117085.
Sharifian-Dorche M, Huot P, Osherov M, et al. Neurological complications of coronavirus infection; a comparative review and lessons learned during the COVID-19 pandemic. J Neurol Sci. 2020;417:117085.
Sharifian-Dorche, M., Huot, P., Osherov, M., Wen, D., Saveriano, A., Giacomini, P. S., Antel, J. P., & Mowla, A. (2020). Neurological complications of coronavirus infection; a comparative review and lessons learned during the COVID-19 pandemic. Journal of the Neurological Sciences, 417, 117085. https://doi.org/10.1016/j.jns.2020.117085
Sharifian-Dorche M, et al. Neurological Complications of Coronavirus Infection; a Comparative Review and Lessons Learned During the COVID-19 Pandemic. J Neurol Sci. 2020 10 15;417:117085. PubMed PMID: 32871412.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Neurological complications of coronavirus infection; a comparative review and lessons learned during the COVID-19 pandemic. AU - Sharifian-Dorche,Maryam, AU - Huot,Philippe, AU - Osherov,Michael, AU - Wen,Dingke, AU - Saveriano,Alexander, AU - Giacomini,Paul S, AU - Antel,Jack P, AU - Mowla,Ashkan, Y1 - 2020/08/07/ PY - 2020/08/04/received PY - 2020/08/05/accepted PY - 2020/9/2/pubmed PY - 2020/9/26/medline PY - 2020/9/2/entrez KW - COVID-19 KW - Coronavirus KW - MERS-CoV KW - Neurological manifestations KW - SARS-CoV-1 SP - 117085 EP - 117085 JF - Journal of the neurological sciences JO - J Neurol Sci VL - 417 N2 - INTRODUCTION: Coronavirus disease-19 (COVID-19) pandemic continues to grow all over the world. Several studies have been performed, focusing on understanding the acute respiratory syndrome and treatment strategies. However, there is growing evidence indicating neurological manifestations occur in patients with COVID-19. Similarly, the other coronaviruses (CoV) epidemics; severe acute respiratory syndrome (SARS-CoV-1) and Middle East respiratory syndrome (MERS-CoV) have been associated with neurological complications. METHODS: This systematic review serves to summarize available information regarding the potential effects of different types of CoV on the nervous system and describes the range of clinical neurological complications that have been reported thus far in COVID-19. RESULTS: Two hundred and twenty-five studies on CoV infections associated neurological manifestations in human were reviewed. Of those, 208 articles were pertinent to COVID-19. The most common neurological complaints in COVID-19 were anosmia, ageusia, and headache, but more serious complications, such as stroke, impairment of consciousness, seizures, and encephalopathy, have also been reported. CONCLUSION: There are several similarities between neurological complications after SARS-CoV-1, MERS-CoV and COVID-19, however, the scope of the epidemics and number of patients are very different. Reports on the neurological complications after and during COVID-19 are growing on a daily basis. Accordingly, comprehensive knowledge of these complications will help health care providers to be attentive to these complications and diagnose and treat them timely. SN - 1878-5883 UR - https://www.unboundmedicine.com/medline/citation/32871412/Neurological_complications_of_coronavirus_infection L2 - https://linkinghub.elsevier.com/retrieve/pii/S0022-510X(20)30422-6 DB - PRIME DP - Unbound Medicine ER -