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Rhabdomyolysis and acute kidney injury in severe COVID-19 infection.
BMJ Case Rep. 2020 Sep 02; 13(9)BC

Abstract

We report the case of a 38-year-old man who presented to the emergency department with fever, myalgia, nausea, vomiting, dry cough, breathlessness and abdominal pain. He was admitted due to hypoxaemia and was diagnosed with SARS-CoV-2 and was subsequently referred to the intensive care unit for intubation and mechanical ventilation. Severe rhabdomyolysis and acute kidney injury developed 4 days later and were suspected after noticing discolouration of the urine and a marked increase in plasma myoglobin levels. Treatment included hydration, forced diuresis and continuous renal replacement therapy. In addition to the coronavirus disease acute respiratory distress syndrome, he was diagnosed with possible SARS-CoV-2-induced myositis with severe rhabdomyolysis and kidney failure. The patient survived and was discharged from intensive care after 12 days, returning home 23 days after hospitalisation, fully mobilised with a partially restored kidney function.

Authors+Show Affiliations

Anaesthesia and Intensive Care Medicine, Region Jonkopings lan, Jonkoping, Sweden knut.taxbro@rjl.se.Anaesthesia and Intensive Care Medicine, Region Jonkopings lan, Jonkoping, Sweden.Anaesthesia and Intensive Care Medicine, Region Jonkopings lan, Jonkoping, Sweden.Anaesthesia and Intensive Care Medicine, Region Jonkopings lan, Jonkoping, Sweden. Infectious Diseases, Region Jonkopings lan, Jonkoping, Jönköping, Sweden.

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

32878841

Citation

Taxbro, Knut, et al. "Rhabdomyolysis and Acute Kidney Injury in Severe COVID-19 Infection." BMJ Case Reports, vol. 13, no. 9, 2020.
Taxbro K, Kahlow H, Wulcan H, et al. Rhabdomyolysis and acute kidney injury in severe COVID-19 infection. BMJ Case Rep. 2020;13(9).
Taxbro, K., Kahlow, H., Wulcan, H., & Fornarve, A. (2020). Rhabdomyolysis and acute kidney injury in severe COVID-19 infection. BMJ Case Reports, 13(9). https://doi.org/10.1136/bcr-2020-237616
Taxbro K, et al. Rhabdomyolysis and Acute Kidney Injury in Severe COVID-19 Infection. BMJ Case Rep. 2020 Sep 2;13(9) PubMed PMID: 32878841.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Rhabdomyolysis and acute kidney injury in severe COVID-19 infection. AU - Taxbro,Knut, AU - Kahlow,Hannes, AU - Wulcan,Hannes, AU - Fornarve,Anna, Y1 - 2020/09/02/ PY - 2020/9/4/entrez PY - 2020/9/4/pubmed PY - 2020/9/12/medline KW - adult intensive care KW - infectious diseases JF - BMJ case reports JO - BMJ Case Rep VL - 13 IS - 9 N2 - We report the case of a 38-year-old man who presented to the emergency department with fever, myalgia, nausea, vomiting, dry cough, breathlessness and abdominal pain. He was admitted due to hypoxaemia and was diagnosed with SARS-CoV-2 and was subsequently referred to the intensive care unit for intubation and mechanical ventilation. Severe rhabdomyolysis and acute kidney injury developed 4 days later and were suspected after noticing discolouration of the urine and a marked increase in plasma myoglobin levels. Treatment included hydration, forced diuresis and continuous renal replacement therapy. In addition to the coronavirus disease acute respiratory distress syndrome, he was diagnosed with possible SARS-CoV-2-induced myositis with severe rhabdomyolysis and kidney failure. The patient survived and was discharged from intensive care after 12 days, returning home 23 days after hospitalisation, fully mobilised with a partially restored kidney function. SN - 1757-790X UR - https://www.unboundmedicine.com/medline/citation/32878841/Rhabdomyolysis_and_acute_kidney_injury_in_severe_COVID_19_infection_ L2 - https://casereports.bmj.com/lookup/pmidlookup?view=long&pmid=32878841 DB - PRIME DP - Unbound Medicine ER -