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Increased healing of gastric and duodenal ulcers in a controlled trial using tripotassium dicitrato-bismuthate.
Med J Aust. 1977 May 28; 1(22):808-12.MJ

Abstract

Thirty-seven outpatients with benign gastric ulcers proved by endoscopy were randomized and treated with tripotassium dicitrato-bismuthate (TDB) and a placebo for four weeks. They were assessed on the basis of symptoms and endoscopy examination. Ulcer healing observed by endoscopy was significantly better in the TDB treated group (18 of 20) than in the placebo treated group (six of 17). There was no statistical difference in symptomatic improvement. Nineteen patients with duodenal ulcers proved by endoscopy were randomized in a double-blind trial and given TDB and a placebo for four weeks. Ulcer healing in the TDB treated group (eight of nine) was significantly better than in the placebo treated group (two of 10). No significant difference was found in the symptomatic improvement of both groups. It is concluded that TDB is an effective agent for the treatment of chronic gastric and duodenal ulcers.

Authors

No affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

329077

Citation

Lee, S P., and G I. Nicholson. "Increased Healing of Gastric and Duodenal Ulcers in a Controlled Trial Using Tripotassium Dicitrato-bismuthate." The Medical Journal of Australia, vol. 1, no. 22, 1977, pp. 808-12.
Lee SP, Nicholson GI. Increased healing of gastric and duodenal ulcers in a controlled trial using tripotassium dicitrato-bismuthate. Med J Aust. 1977;1(22):808-12.
Lee, S. P., & Nicholson, G. I. (1977). Increased healing of gastric and duodenal ulcers in a controlled trial using tripotassium dicitrato-bismuthate. The Medical Journal of Australia, 1(22), 808-12.
Lee SP, Nicholson GI. Increased Healing of Gastric and Duodenal Ulcers in a Controlled Trial Using Tripotassium Dicitrato-bismuthate. Med J Aust. 1977 May 28;1(22):808-12. PubMed PMID: 329077.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Increased healing of gastric and duodenal ulcers in a controlled trial using tripotassium dicitrato-bismuthate. AU - Lee,S P, AU - Nicholson,G I, PY - 1977/5/28/pubmed PY - 1977/5/28/medline PY - 1977/5/28/entrez SP - 808 EP - 12 JF - The Medical journal of Australia JO - Med J Aust VL - 1 IS - 22 N2 - Thirty-seven outpatients with benign gastric ulcers proved by endoscopy were randomized and treated with tripotassium dicitrato-bismuthate (TDB) and a placebo for four weeks. They were assessed on the basis of symptoms and endoscopy examination. Ulcer healing observed by endoscopy was significantly better in the TDB treated group (18 of 20) than in the placebo treated group (six of 17). There was no statistical difference in symptomatic improvement. Nineteen patients with duodenal ulcers proved by endoscopy were randomized in a double-blind trial and given TDB and a placebo for four weeks. Ulcer healing in the TDB treated group (eight of nine) was significantly better than in the placebo treated group (two of 10). No significant difference was found in the symptomatic improvement of both groups. It is concluded that TDB is an effective agent for the treatment of chronic gastric and duodenal ulcers. SN - 0025-729X UR - https://www.unboundmedicine.com/medline/citation/329077/Increased_healing_of_gastric_and_duodenal_ulcers_in_a_controlled_trial_using_tripotassium_dicitrato_bismuthate_ L2 - https://doi.org/10.5694/j.1326-5377.1977.tb131140.x DB - PRIME DP - Unbound Medicine ER -