Tags

Type your tag names separated by a space and hit enter

Comparative efficacy of permethrin 1%, lindane 1%, and dimeticone 4% for the treatment of head louse infestation in Iran.
Environ Sci Pollut Res Int. 2021 Jan; 28(3):3506-3514.ES

Abstract

Pediculosis capitis occurs worldwide. Children in the age group of 5-13 years are the ordinary victims. Population-based studies show that the prevalence of pediculosis is 1.6-13.4% in various regions of Iran. In this observer-blinded trial, we conducted a study to evaluate the comparative efficacy and safety of permethrin 1% and lindane 1% shampoos and dimeticone 4% lotion to cure head lice infestation in children aged 7-13 years in female primary schools in Ahvaz City, Iran. Children with head lice were randomized to receive each treatment. Two applications of permethrin 1% or dimeticone 4% were done, 1 week apart. However, lindane 1% was used just once for treatment cases. Data analysis was done using SPSS software. Recovery differences between the groups were tested using the chi-squared test. Four hundred forty-four louse-infested schoolgirls were randomly treated with them. Permethrin, lindane, dimeticone, and placebo produced the recovery rates 56.8, 31.5, 51.4, and 10.8% on day 2 post-treatment, respectively. Cure rates were in the permethrin group on days 8 and 15, respectively, 69.4 and 90.1%. The success rates were in the lindane group on days 8 and 15, respectively, 73 and 86.5%. The success rates were in the dimeticone group on days 8 and 15, respectively, 60.4 and 94.6%. It is recommended dimeticone lotion (4%) as a very effective and safe pediculicide for pediculosis control. With proper application, dimethicone can rapidly cure head lice infestation with minimal reinfestation.

Authors+Show Affiliations

Department of Medical Entomology, School of Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. Hamid.Kassiri@yahoo.com.Department of Medical Entomology, School of Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.Department of Bio-Statistics, School of Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32918266

Citation

Kassiri, Hamid, et al. "Comparative Efficacy of Permethrin 1%, Lindane 1%, and Dimeticone 4% for the Treatment of Head Louse Infestation in Iran." Environmental Science and Pollution Research International, vol. 28, no. 3, 2021, pp. 3506-3514.
Kassiri H, Fahdani AE, Cheraghian B. Comparative efficacy of permethrin 1%, lindane 1%, and dimeticone 4% for the treatment of head louse infestation in Iran. Environ Sci Pollut Res Int. 2021;28(3):3506-3514.
Kassiri, H., Fahdani, A. E., & Cheraghian, B. (2021). Comparative efficacy of permethrin 1%, lindane 1%, and dimeticone 4% for the treatment of head louse infestation in Iran. Environmental Science and Pollution Research International, 28(3), 3506-3514. https://doi.org/10.1007/s11356-020-10686-3
Kassiri H, Fahdani AE, Cheraghian B. Comparative Efficacy of Permethrin 1%, Lindane 1%, and Dimeticone 4% for the Treatment of Head Louse Infestation in Iran. Environ Sci Pollut Res Int. 2021;28(3):3506-3514. PubMed PMID: 32918266.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparative efficacy of permethrin 1%, lindane 1%, and dimeticone 4% for the treatment of head louse infestation in Iran. AU - Kassiri,Hamid, AU - Fahdani,Atefe Ebrahimi, AU - Cheraghian,Bahman, Y1 - 2020/09/12/ PY - 2020/07/01/received PY - 2020/08/30/accepted PY - 2020/9/13/pubmed PY - 2021/1/9/medline PY - 2020/9/12/entrez KW - Children KW - Dimeticone KW - Head lice KW - Iran KW - Lindane KW - Pediculosis KW - Permethrin KW - Primary schools SP - 3506 EP - 3514 JF - Environmental science and pollution research international JO - Environ Sci Pollut Res Int VL - 28 IS - 3 N2 - Pediculosis capitis occurs worldwide. Children in the age group of 5-13 years are the ordinary victims. Population-based studies show that the prevalence of pediculosis is 1.6-13.4% in various regions of Iran. In this observer-blinded trial, we conducted a study to evaluate the comparative efficacy and safety of permethrin 1% and lindane 1% shampoos and dimeticone 4% lotion to cure head lice infestation in children aged 7-13 years in female primary schools in Ahvaz City, Iran. Children with head lice were randomized to receive each treatment. Two applications of permethrin 1% or dimeticone 4% were done, 1 week apart. However, lindane 1% was used just once for treatment cases. Data analysis was done using SPSS software. Recovery differences between the groups were tested using the chi-squared test. Four hundred forty-four louse-infested schoolgirls were randomly treated with them. Permethrin, lindane, dimeticone, and placebo produced the recovery rates 56.8, 31.5, 51.4, and 10.8% on day 2 post-treatment, respectively. Cure rates were in the permethrin group on days 8 and 15, respectively, 69.4 and 90.1%. The success rates were in the lindane group on days 8 and 15, respectively, 73 and 86.5%. The success rates were in the dimeticone group on days 8 and 15, respectively, 60.4 and 94.6%. It is recommended dimeticone lotion (4%) as a very effective and safe pediculicide for pediculosis control. With proper application, dimethicone can rapidly cure head lice infestation with minimal reinfestation. SN - 1614-7499 UR - https://www.unboundmedicine.com/medline/citation/32918266/Comparative_efficacy_of_permethrin_1_lindane_1_and_dimeticone_4_for_the_treatment_of_head_louse_infestation_in_Iran_ L2 - https://dx.doi.org/10.1007/s11356-020-10686-3 DB - PRIME DP - Unbound Medicine ER -