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Fangcang Shelter Hospital in Wuhan: A radiographic report on a cohort of 98 COVID-19 patients.
Int J Med Sci. 2020; 17(14):2125-2132.IJ

Abstract

Objectives:

To present the temporal changes of CT manifestations in COVID-19 patients from a single fangcang shelter hospital and to facilitate the understanding of the disease course. Materials and

Methods:

This retrospective study included 98 patients (males: females, 43:55, mean year, 49±12 years) with confirmed COVID-19 at Jianghan fangcang shelter hospital admitted between Feb 05, 2020, and Feb 09, 2020, who had initial chest CTs at our hospital. Radiographic features and CT scores were analyzed.

Results:

A total of 267 CT scans of 98 patients were evaluated. Our study showed a high median total CT score of 7 within the first week from symptom onset, peaked in the 2nd week at 10, followed by persistently high levels of CT score with 9.5, 7 and 7 for the week 3, 4, and >4, respectively, and a prolonged median disease course (30 days, the median interval between the onset of initial symptoms and discharge). Ground-glass opacity (GGO) (58%, 41/71) was the earliest and most frequent finding in week 1. Consolidation (26%, 14/53) and mixed pattern (40%, 21/53) were predominant patterns in 2nd week. GGO and reticular were the main patterns of later phase CT scans in patients with relatively advanced diseases who had longer illness duration (≥4 weeks). Among the 94 CT abnormalities obtained within 3 days from the twice RT-PCR test turned negative, the mixed pattern was mainly presented in patients with disease duration of 2-3 weeks, for GGO and reticular were common during the whole course.

Conclusion:

Discharged patients from fangcang shelter hospital demonstrated a high extent of lung abnormalities on CT within the first week from symptom onset, peaked at 2nd week, followed by persistence of high levels and a prolonged median disease course. GGO was the predominant pattern in week 1, consolidation and mixed pattern in 2nd week, whereas GGO and reticular patterns in later stages (≥4 weeks).

Authors+Show Affiliations

Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China. Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430022, China.Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China. Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430022, China.Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China. Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430022, China.MSC Clinical & Technical Solutions, Philips Healthcare, Beijing, 100000, China.Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China. Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430022, China.Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China. Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430022, China.Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China. Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430022, China.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32922173

Citation

Guo, Tingting, et al. "Fangcang Shelter Hospital in Wuhan: a Radiographic Report On a Cohort of 98 COVID-19 Patients." International Journal of Medical Sciences, vol. 17, no. 14, 2020, pp. 2125-2132.
Guo T, Liu X, Xu C, et al. Fangcang Shelter Hospital in Wuhan: A radiographic report on a cohort of 98 COVID-19 patients. Int J Med Sci. 2020;17(14):2125-2132.
Guo, T., Liu, X., Xu, C., Wang, J., Yang, L., Shi, H., & Dai, M. (2020). Fangcang Shelter Hospital in Wuhan: A radiographic report on a cohort of 98 COVID-19 patients. International Journal of Medical Sciences, 17(14), 2125-2132. https://doi.org/10.7150/ijms.48074
Guo T, et al. Fangcang Shelter Hospital in Wuhan: a Radiographic Report On a Cohort of 98 COVID-19 Patients. Int J Med Sci. 2020;17(14):2125-2132. PubMed PMID: 32922173.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Fangcang Shelter Hospital in Wuhan: A radiographic report on a cohort of 98 COVID-19 patients. AU - Guo,Tingting, AU - Liu,Xiaoming, AU - Xu,Cihao, AU - Wang,Jiazheng, AU - Yang,Lian, AU - Shi,Heshui, AU - Dai,Meng, Y1 - 2020/07/30/ PY - 2020/05/11/received PY - 2020/07/22/accepted PY - 2020/9/14/entrez PY - 2020/9/15/pubmed PY - 2020/9/23/medline KW - CT KW - Coronavirus disease 2019 (COVID-19) KW - ground-glass opacity (GGO) SP - 2125 EP - 2132 JF - International journal of medical sciences JO - Int J Med Sci VL - 17 IS - 14 N2 - Objectives: To present the temporal changes of CT manifestations in COVID-19 patients from a single fangcang shelter hospital and to facilitate the understanding of the disease course. Materials and Methods: This retrospective study included 98 patients (males: females, 43:55, mean year, 49±12 years) with confirmed COVID-19 at Jianghan fangcang shelter hospital admitted between Feb 05, 2020, and Feb 09, 2020, who had initial chest CTs at our hospital. Radiographic features and CT scores were analyzed. Results: A total of 267 CT scans of 98 patients were evaluated. Our study showed a high median total CT score of 7 within the first week from symptom onset, peaked in the 2nd week at 10, followed by persistently high levels of CT score with 9.5, 7 and 7 for the week 3, 4, and >4, respectively, and a prolonged median disease course (30 days, the median interval between the onset of initial symptoms and discharge). Ground-glass opacity (GGO) (58%, 41/71) was the earliest and most frequent finding in week 1. Consolidation (26%, 14/53) and mixed pattern (40%, 21/53) were predominant patterns in 2nd week. GGO and reticular were the main patterns of later phase CT scans in patients with relatively advanced diseases who had longer illness duration (≥4 weeks). Among the 94 CT abnormalities obtained within 3 days from the twice RT-PCR test turned negative, the mixed pattern was mainly presented in patients with disease duration of 2-3 weeks, for GGO and reticular were common during the whole course. Conclusion: Discharged patients from fangcang shelter hospital demonstrated a high extent of lung abnormalities on CT within the first week from symptom onset, peaked at 2nd week, followed by persistence of high levels and a prolonged median disease course. GGO was the predominant pattern in week 1, consolidation and mixed pattern in 2nd week, whereas GGO and reticular patterns in later stages (≥4 weeks). SN - 1449-1907 UR - https://www.unboundmedicine.com/medline/citation/32922173/Fangcang_Shelter_Hospital_in_Wuhan:_A_radiographic_report_on_a_cohort_of_98_COVID_19_patients_ L2 - https://www.medsci.org/v17p2125.htm DB - PRIME DP - Unbound Medicine ER -