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Ability of the phenolic glycolipid-I antigen of M. leprae to elicit a positive Mitsuda response in the armadillo (Dasypus novemcinctus).
Int J Lepr Other Mycobact Dis. 1987 Jun; 55(2):299-304.IJ

Abstract

Three lepromin-positive armadillos and three lepromin-negative armadillos were tested intradermally with 100 micrograms of phenolic glycolipid-I (PGL-I) in 0.1 ml of normal saline. Positive delayed-hypersensitivity granulomas at 21 days in the lepromin-positive animals and negative responses in the lepromin-negative animals were obtained. These observations suggest that purified PGL-I is capable of eliciting cell-mediated immune or delayed-hypersensitivity responses in animals sensitized to Mycobacterium leprae.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

3298476

Citation

Job, C K., et al. "Ability of the Phenolic glycolipid-I Antigen of M. Leprae to Elicit a Positive Mitsuda Response in the Armadillo (Dasypus Novemcinctus)." International Journal of Leprosy and Other Mycobacterial Diseases : Official Organ of the International Leprosy Association, vol. 55, no. 2, 1987, pp. 299-304.
Job CK, Sanchez RM, McCormick GT, et al. Ability of the phenolic glycolipid-I antigen of M. leprae to elicit a positive Mitsuda response in the armadillo (Dasypus novemcinctus). Int J Lepr Other Mycobact Dis. 1987;55(2):299-304.
Job, C. K., Sanchez, R. M., McCormick, G. T., & Hastings, R. C. (1987). Ability of the phenolic glycolipid-I antigen of M. leprae to elicit a positive Mitsuda response in the armadillo (Dasypus novemcinctus). International Journal of Leprosy and Other Mycobacterial Diseases : Official Organ of the International Leprosy Association, 55(2), 299-304.
Job CK, et al. Ability of the Phenolic glycolipid-I Antigen of M. Leprae to Elicit a Positive Mitsuda Response in the Armadillo (Dasypus Novemcinctus). Int J Lepr Other Mycobact Dis. 1987;55(2):299-304. PubMed PMID: 3298476.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Ability of the phenolic glycolipid-I antigen of M. leprae to elicit a positive Mitsuda response in the armadillo (Dasypus novemcinctus). AU - Job,C K, AU - Sanchez,R M, AU - McCormick,G T, AU - Hastings,R C, PY - 1987/6/1/pubmed PY - 1987/6/1/medline PY - 1987/6/1/entrez SP - 299 EP - 304 JF - International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association JO - Int J Lepr Other Mycobact Dis VL - 55 IS - 2 N2 - Three lepromin-positive armadillos and three lepromin-negative armadillos were tested intradermally with 100 micrograms of phenolic glycolipid-I (PGL-I) in 0.1 ml of normal saline. Positive delayed-hypersensitivity granulomas at 21 days in the lepromin-positive animals and negative responses in the lepromin-negative animals were obtained. These observations suggest that purified PGL-I is capable of eliciting cell-mediated immune or delayed-hypersensitivity responses in animals sensitized to Mycobacterium leprae. SN - 0148-916X UR - https://www.unboundmedicine.com/medline/citation/3298476/Ability_of_the_phenolic_glycolipid_I_antigen_of_M__leprae_to_elicit_a_positive_Mitsuda_response_in_the_armadillo__Dasypus_novemcinctus__ DB - PRIME DP - Unbound Medicine ER -