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Ability of the phenolic glycolipid-I antigen of M. leprae to elicit a positive Mitsuda response in the armadillo (Dasypus novemcinctus).
Int J Lepr Other Mycobact Dis. 1987 Jun; 55(2):299-304.IJ

Abstract

Three lepromin-positive armadillos and three lepromin-negative armadillos were tested intradermally with 100 micrograms of phenolic glycolipid-I (PGL-I) in 0.1 ml of normal saline. Positive delayed-hypersensitivity granulomas at 21 days in the lepromin-positive animals and negative responses in the lepromin-negative animals were obtained. These observations suggest that purified PGL-I is capable of eliciting cell-mediated immune or delayed-hypersensitivity responses in animals sensitized to Mycobacterium leprae.

Authors

Job CK
No affiliation info available
Sanchez RM
No affiliation info available
McCormick GT
No affiliation info available
Hastings RC
No affiliation info available

MeSH

AnimalsAntigens, BacterialArmadillosGlycolipidsHypersensitivity, DelayedLeprominMycobacterium lepraeXenarthra

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

3298476

Citation

Job, C K., et al. "Ability of the Phenolic glycolipid-I Antigen of M. Leprae to Elicit a Positive Mitsuda Response in the Armadillo (Dasypus Novemcinctus)." International Journal of Leprosy and Other Mycobacterial Diseases : Official Organ of the International Leprosy Association, vol. 55, no. 2, 1987, pp. 299-304.
Job CK, Sanchez RM, McCormick GT, et al. Ability of the phenolic glycolipid-I antigen of M. leprae to elicit a positive Mitsuda response in the armadillo (Dasypus novemcinctus). Int J Lepr Other Mycobact Dis. 1987;55(2):299-304.
Job, C. K., Sanchez, R. M., McCormick, G. T., & Hastings, R. C. (1987). Ability of the phenolic glycolipid-I antigen of M. leprae to elicit a positive Mitsuda response in the armadillo (Dasypus novemcinctus). International Journal of Leprosy and Other Mycobacterial Diseases : Official Organ of the International Leprosy Association, 55(2), 299-304.
Job CK, et al. Ability of the Phenolic glycolipid-I Antigen of M. Leprae to Elicit a Positive Mitsuda Response in the Armadillo (Dasypus Novemcinctus). Int J Lepr Other Mycobact Dis. 1987;55(2):299-304. PubMed PMID: 3298476.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Ability of the phenolic glycolipid-I antigen of M. leprae to elicit a positive Mitsuda response in the armadillo (Dasypus novemcinctus). AU - Job,C K, AU - Sanchez,R M, AU - McCormick,G T, AU - Hastings,R C, PY - 1987/6/1/pubmed PY - 1987/6/1/medline PY - 1987/6/1/entrez SP - 299 EP - 304 JF - International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association JO - Int J Lepr Other Mycobact Dis VL - 55 IS - 2 N2 - Three lepromin-positive armadillos and three lepromin-negative armadillos were tested intradermally with 100 micrograms of phenolic glycolipid-I (PGL-I) in 0.1 ml of normal saline. Positive delayed-hypersensitivity granulomas at 21 days in the lepromin-positive animals and negative responses in the lepromin-negative animals were obtained. These observations suggest that purified PGL-I is capable of eliciting cell-mediated immune or delayed-hypersensitivity responses in animals sensitized to Mycobacterium leprae. SN - 0148-916X UR - https://www.unboundmedicine.com/medline/citation/3298476/Ability_of_the_phenolic_glycolipid_I_antigen_of_M__leprae_to_elicit_a_positive_Mitsuda_response_in_the_armadillo__Dasypus_novemcinctus__ DB - PRIME DP - Unbound Medicine ER -