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Therapeutic Uses of Red Macroalgae.
Molecules. 2020 Sep 25; 25(19)M

Abstract

Red Seaweed "Rhodophyta" are an important group of macroalgae that include approximately 7000 species. They are a rich source of structurally diverse bioactive constituents, including protein, sulfated polysaccharides, pigments, polyunsaturated fatty acids, vitamins, minerals, and phenolic compounds with nutritional, medical, and industrial importance. Polysaccharides are the main components in the cell wall of red algae and represent about 40-50% of the dry weight, which are extensively utilized in industry and pharmaceutical compounds, due to their thickening and gelling properties. The hydrocolloids galactans carrageenans and agars are the main red seaweed cell wall polysaccharides, which had broad-spectrum therapeutic characters. Generally, the chemical contents of seaweed are different according to the algal species, growth stage, environment, and external conditions, e.g., the temperature of the water, light intensity, nutrient concentrations in the ecosystem. Economically, they can be recommended as a substitute source for natural ingredients that contribute to a broad range of bioactivities like cancer therapy, anti-inflammatory agents, and acetylcholinesterase inhibitory. This review touches on the main points of the pharmaceutical applications of red seaweed, as well as the exploitation of their specific compounds and secondary metabolites with vital roles.

Authors+Show Affiliations

National Institute of Oceanography and Fisheries, NIOF, Alexandria 21556, Egypt.Pharmaceutical Sciences Department, College of Pharmacy, Princess Nourah bint Abdulrahman University, Riyadh 11671, Saudi Arabia.Botany Department, Faculty of Science, Tanta University, Tanta 31527, Egypt.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

32992919

Citation

Ismail, Mona M., et al. "Therapeutic Uses of Red Macroalgae." Molecules (Basel, Switzerland), vol. 25, no. 19, 2020.
Ismail MM, Alotaibi BS, El-Sheekh MM. Therapeutic Uses of Red Macroalgae. Molecules. 2020;25(19).
Ismail, M. M., Alotaibi, B. S., & El-Sheekh, M. M. (2020). Therapeutic Uses of Red Macroalgae. Molecules (Basel, Switzerland), 25(19). https://doi.org/10.3390/molecules25194411
Ismail MM, Alotaibi BS, El-Sheekh MM. Therapeutic Uses of Red Macroalgae. Molecules. 2020 Sep 25;25(19) PubMed PMID: 32992919.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Therapeutic Uses of Red Macroalgae. AU - Ismail,Mona M, AU - Alotaibi,Badriyah S, AU - El-Sheekh,Mostafa M, Y1 - 2020/09/25/ PY - 2020/09/10/received PY - 2020/09/21/revised PY - 2020/09/23/accepted PY - 2020/9/30/entrez PY - 2020/10/1/pubmed PY - 2021/3/19/medline KW - Rhodophyta KW - bioactive compounds KW - drugs KW - seaweed JF - Molecules (Basel, Switzerland) JO - Molecules VL - 25 IS - 19 N2 - Red Seaweed "Rhodophyta" are an important group of macroalgae that include approximately 7000 species. They are a rich source of structurally diverse bioactive constituents, including protein, sulfated polysaccharides, pigments, polyunsaturated fatty acids, vitamins, minerals, and phenolic compounds with nutritional, medical, and industrial importance. Polysaccharides are the main components in the cell wall of red algae and represent about 40-50% of the dry weight, which are extensively utilized in industry and pharmaceutical compounds, due to their thickening and gelling properties. The hydrocolloids galactans carrageenans and agars are the main red seaweed cell wall polysaccharides, which had broad-spectrum therapeutic characters. Generally, the chemical contents of seaweed are different according to the algal species, growth stage, environment, and external conditions, e.g., the temperature of the water, light intensity, nutrient concentrations in the ecosystem. Economically, they can be recommended as a substitute source for natural ingredients that contribute to a broad range of bioactivities like cancer therapy, anti-inflammatory agents, and acetylcholinesterase inhibitory. This review touches on the main points of the pharmaceutical applications of red seaweed, as well as the exploitation of their specific compounds and secondary metabolites with vital roles. SN - 1420-3049 UR - https://www.unboundmedicine.com/medline/citation/32992919/Therapeutic_Uses_of_Red_Macroalgae_ DB - PRIME DP - Unbound Medicine ER -