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Vaginal delivery in women with COVID-19: report of two cases.
BMC Pregnancy Childbirth. 2020 Oct 02; 20(1):580.BP

Abstract

BACKGROUND

During the ongoing global outbreak of COVID-19, pregnant women who are susceptible to COVID-19 should be highly concerned. The issue of vertical transmission and the possibility of neonatal infection is a major concern.

CASE PRESENTATION

Case 1: A 35-year-old pregnant woman with a gestational age of 37 weeks and 6 days was admitted to our hospital at the point of giving birth. Except for the abnormalities in her chest CT image, she was asymptomatic. She had an uncomplicated spontaneous vaginal delivery, and her infant was discharged home for isolation. Because of the positive result of the maternal swabs for SARS-CoV-2 obtained on the 2nd day after sampling, we transferred the mother to the designated hospital and followed up with her by telephone interviews. Luckily, it was confirmed on February 23 that the newborn did not develop any COVID-19 symptoms after observation for 14 days after birth. Case 2: Another pregnant woman, with a gestational age of 38 weeks and 2 days, was also admitted to our hospital because of spontaneous labor with cervical dilation of 5 cm. Since she had the typical manifestations of COVID-19, including cough, lymphopenia, and abnormal chest CT images, she was highly suspected of having COVID-19. Based on the experience from case 1, we helped the mother deliver a healthy baby by vaginal delivery. On the 2nd day after delivery, the maternal nasopharyngeal swab result was positive, while the infant's result was negative.

CONCLUSION

There is still insufficient evidence supporting maternal-fetal vertical transmission for COVID-19-infected mothers in late pregnancy, and vaginal delivery may not increase the possibility of neonatal infection.

Authors+Show Affiliations

Department of Obstetrics, Maternal and Child Health Hospital of Hubei Province, No. 745 Wuluo Road, Hongshan District, Wuhan City, 430070, Hubei Province, China.Department of Obstetrics, Maternal and Child Health Hospital of Hubei Province, No. 745 Wuluo Road, Hongshan District, Wuhan City, 430070, Hubei Province, China. Department of Obstetrics, The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, Yuzhong District, Chongqing, 400016, China.Department of Obstetrics, Maternal and Child Health Hospital of Hubei Province, No. 745 Wuluo Road, Hongshan District, Wuhan City, 430070, Hubei Province, China.Department of Obstetrics, Maternal and Child Health Hospital of Hubei Province, No. 745 Wuluo Road, Hongshan District, Wuhan City, 430070, Hubei Province, China.Department of Obstetrics, Maternal and Child Health Hospital of Hubei Province, No. 745 Wuluo Road, Hongshan District, Wuhan City, 430070, Hubei Province, China. sun821ch@126.com.

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

33008308

Citation

Cao, Dongmei, et al. "Vaginal Delivery in Women With COVID-19: Report of Two Cases." BMC Pregnancy and Childbirth, vol. 20, no. 1, 2020, p. 580.
Cao D, Chen M, Peng M, et al. Vaginal delivery in women with COVID-19: report of two cases. BMC Pregnancy Childbirth. 2020;20(1):580.
Cao, D., Chen, M., Peng, M., Yin, H., & Sun, G. (2020). Vaginal delivery in women with COVID-19: report of two cases. BMC Pregnancy and Childbirth, 20(1), 580. https://doi.org/10.1186/s12884-020-03281-4
Cao D, et al. Vaginal Delivery in Women With COVID-19: Report of Two Cases. BMC Pregnancy Childbirth. 2020 Oct 2;20(1):580. PubMed PMID: 33008308.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Vaginal delivery in women with COVID-19: report of two cases. AU - Cao,Dongmei, AU - Chen,Miaomiao, AU - Peng,Min, AU - Yin,Heng, AU - Sun,Guoqiang, Y1 - 2020/10/02/ PY - 2020/03/04/received PY - 2020/09/23/accepted PY - 2020/10/3/entrez PY - 2020/10/4/pubmed PY - 2020/10/10/medline KW - COVID-19 KW - Case report KW - Intrauterine vertical transmission KW - Vaginal delivery SP - 580 EP - 580 JF - BMC pregnancy and childbirth JO - BMC Pregnancy Childbirth VL - 20 IS - 1 N2 - BACKGROUND: During the ongoing global outbreak of COVID-19, pregnant women who are susceptible to COVID-19 should be highly concerned. The issue of vertical transmission and the possibility of neonatal infection is a major concern. CASE PRESENTATION: Case 1: A 35-year-old pregnant woman with a gestational age of 37 weeks and 6 days was admitted to our hospital at the point of giving birth. Except for the abnormalities in her chest CT image, she was asymptomatic. She had an uncomplicated spontaneous vaginal delivery, and her infant was discharged home for isolation. Because of the positive result of the maternal swabs for SARS-CoV-2 obtained on the 2nd day after sampling, we transferred the mother to the designated hospital and followed up with her by telephone interviews. Luckily, it was confirmed on February 23 that the newborn did not develop any COVID-19 symptoms after observation for 14 days after birth. Case 2: Another pregnant woman, with a gestational age of 38 weeks and 2 days, was also admitted to our hospital because of spontaneous labor with cervical dilation of 5 cm. Since she had the typical manifestations of COVID-19, including cough, lymphopenia, and abnormal chest CT images, she was highly suspected of having COVID-19. Based on the experience from case 1, we helped the mother deliver a healthy baby by vaginal delivery. On the 2nd day after delivery, the maternal nasopharyngeal swab result was positive, while the infant's result was negative. CONCLUSION: There is still insufficient evidence supporting maternal-fetal vertical transmission for COVID-19-infected mothers in late pregnancy, and vaginal delivery may not increase the possibility of neonatal infection. SN - 1471-2393 UR - https://www.unboundmedicine.com/medline/citation/33008308/Vaginal_delivery_in_women_with_COVID_19:_report_of_two_cases_ L2 - https://bmcpregnancychildbirth.biomedcentral.com/articles/10.1186/s12884-020-03281-4 DB - PRIME DP - Unbound Medicine ER -