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Prediction of Death with the FRAIL-NH in Institutionalized Older Adults: A Longitudinal Study from a Middle-Income Country.
J Nutr Health Aging. 2020; 24(8):817-820.JN

Abstract

BACKGROUND/OBJECTIVES

Frailty is common in nursing homes. However, few studies reported longitudinal validation for death prediction or cut-off scores with the FRAIL-NH, which is designed to be used in nursing homes. Moreover, no studies came from Latin America, where frailty is highly prevalent. Our objectives were to evaluate (1) the prevalence of frailty according to the FRAIL-NH scale, and (2) its association to and the best cut-off score for predicting death after 12 months.

DESIGN

longitudinal study with 12-month follow-up.

SETTING

6 nursing homes in southwest of Brazil.

PARTICIPANTS

293 residents with 60 years old or more.

METHODS

Frailty was evaluated through the FRAIL-NH scale. Logistic regression was used to estimate the associated between frailty and mortality adjusted for age and sex. ROC curve was used to evaluate the accuracy of the scale for mortality prediction.

RESULTS

Frailty was prevalent (47.4%) and was associated with death (odds ratio=1.31, 95% confidence interval [CI]=1.18-1.48, p<0.001). The area under the curve was 0.741 (95%CI=0.68-0.79). The sensitivity and specificity of the FRAIL-NH scale according to the best value of the Youden Index was 72.9% and 66.5%, respectively, for a cut-off > 8 points.

CONCLUSIONS

Frailty is prevalent in nursing homes according to the FRAIL-NH and it was associated with one-year prediction of death for a cut-off > 8 points.

Authors+Show Affiliations

Ivan Aprahamian, MD, MS, PhD, FACP. Group of Investigation on Multimorbidity and Mental Health in Aging (GIMMA), Division of Geriatrics, Department of Internal Medicine, Faculty of Medicine of Jundiaí. 250 Francisco Telles st. ZIP 13202-550. Jundiaí, Brazil.E-mail: ivan.aprahamian@gmail.com. Tweeter: @IAprahamian.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

33009530

Citation

Vasconcellos Romanini, C, et al. "Prediction of Death With the FRAIL-NH in Institutionalized Older Adults: a Longitudinal Study From a Middle-Income Country." The Journal of Nutrition, Health & Aging, vol. 24, no. 8, 2020, pp. 817-820.
Vasconcellos Romanini C, Vilas Boas P, Cecato JF, et al. Prediction of Death with the FRAIL-NH in Institutionalized Older Adults: A Longitudinal Study from a Middle-Income Country. J Nutr Health Aging. 2020;24(8):817-820.
Vasconcellos Romanini, C., Vilas Boas, P., Cecato, J. F., Robello, E., Borges, M. K., Martinelli, J. E., & Aprahamian, I. (2020). Prediction of Death with the FRAIL-NH in Institutionalized Older Adults: A Longitudinal Study from a Middle-Income Country. The Journal of Nutrition, Health & Aging, 24(8), 817-820. https://doi.org/10.1007/s12603-020-1464-7
Vasconcellos Romanini C, et al. Prediction of Death With the FRAIL-NH in Institutionalized Older Adults: a Longitudinal Study From a Middle-Income Country. J Nutr Health Aging. 2020;24(8):817-820. PubMed PMID: 33009530.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prediction of Death with the FRAIL-NH in Institutionalized Older Adults: A Longitudinal Study from a Middle-Income Country. AU - Vasconcellos Romanini,C, AU - Vilas Boas,P, AU - Cecato,J F, AU - Robello,E, AU - Borges,M K, AU - Martinelli,J E, AU - Aprahamian,I, PY - 2020/10/3/entrez PY - 2020/10/4/pubmed PY - 2021/2/4/medline KW - FRAIL-NH KW - Frailty KW - mortality KW - nursing home KW - older adults SP - 817 EP - 820 JF - The journal of nutrition, health & aging JO - J Nutr Health Aging VL - 24 IS - 8 N2 - BACKGROUND/OBJECTIVES: Frailty is common in nursing homes. However, few studies reported longitudinal validation for death prediction or cut-off scores with the FRAIL-NH, which is designed to be used in nursing homes. Moreover, no studies came from Latin America, where frailty is highly prevalent. Our objectives were to evaluate (1) the prevalence of frailty according to the FRAIL-NH scale, and (2) its association to and the best cut-off score for predicting death after 12 months. DESIGN: longitudinal study with 12-month follow-up. SETTING: 6 nursing homes in southwest of Brazil. PARTICIPANTS: 293 residents with 60 years old or more. METHODS: Frailty was evaluated through the FRAIL-NH scale. Logistic regression was used to estimate the associated between frailty and mortality adjusted for age and sex. ROC curve was used to evaluate the accuracy of the scale for mortality prediction. RESULTS: Frailty was prevalent (47.4%) and was associated with death (odds ratio=1.31, 95% confidence interval [CI]=1.18-1.48, p<0.001). The area under the curve was 0.741 (95%CI=0.68-0.79). The sensitivity and specificity of the FRAIL-NH scale according to the best value of the Youden Index was 72.9% and 66.5%, respectively, for a cut-off > 8 points. CONCLUSIONS: Frailty is prevalent in nursing homes according to the FRAIL-NH and it was associated with one-year prediction of death for a cut-off > 8 points. SN - 1760-4788 UR - https://www.unboundmedicine.com/medline/citation/33009530/Prediction_of_Death_with_the_FRAIL_NH_in_Institutionalized_Older_Adults:_A_Longitudinal_Study_from_a_Middle_Income_Country_ DB - PRIME DP - Unbound Medicine ER -