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Clinical, magnetic resonance imaging and histologic findings of canine thoracolumbar discal pseudocyst: 8 cases (2014-2019).
J Small Anim Pract. 2021 01; 62(1):28-32.JS

Abstract

OBJECTIVE

To report the clinical and MRI features, and histologic findings of thoracolumbar discal pseudocyst in dogs.

MATERIALS AND METHODS

The records of eight dogs with thoracolumbar discal cyst-like structures were retrospectively collected to record their clinical signs, MRI features and surgical and histologic findings.

RESULTS

Eight dogs with surgically and histologically confirmed thoracolumbar discal pseudocysts were included in the case series. Six dogs presented with acute onset and two dogs presented with subacute onset of thoracolumbar myelopathy. MRI showed compressive thoracolumbar myelopathy due to a round to oval-shaped epidural mass lesion communicating with the intervertebral disc, iso/hypointense on T1WI and mostly hyperintense on T2WI, associated with a variable contrast-enhancing wall, compatible with a cyst-like structure. These structures were surgically visualised and removed through a mini-hemilaminectomy or hemilaminectomy and submitted for histologic investigation. One dog also underwent cytologic examination of the cystic content. Similar to that in humans, histology revealed a cyst-like nature with a wall consisting of dense fibrous connective tissue containing clusters of chondroid cells accompanied by groups of notochordal cells and occasional erythrocytes; however, a real epithelial lining was missing and the term pseudocyst seemed more appropriate.

CLINICAL SIGNIFICANCE

This report describes clinical signs, and MRI and histologic findings of discal pseudocysts in dogs with thoracolumbar myelopathy. Despite being rare, discal pseudocysts should be considered as a differential diagnosis in dogs with acute onset thoracolumbar myelopathy.

Authors+Show Affiliations

Diagnostica Piccoli Animali, Via Caldierino 13, 36030, Zugliano (VI), Italy.Diagnostica Piccoli Animali, Via Caldierino 13, 36030, Zugliano (VI), Italy.Diagnostica Piccoli Animali, Via Caldierino 13, 36030, Zugliano (VI), Italy.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

33058203

Citation

Fiorentino, E, et al. "Clinical, Magnetic Resonance Imaging and Histologic Findings of Canine Thoracolumbar Discal Pseudocyst: 8 Cases (2014-2019)." The Journal of Small Animal Practice, vol. 62, no. 1, 2021, pp. 28-32.
Fiorentino E, Gasparinetti N, Falzone C. Clinical, magnetic resonance imaging and histologic findings of canine thoracolumbar discal pseudocyst: 8 cases (2014-2019). J Small Anim Pract. 2021;62(1):28-32.
Fiorentino, E., Gasparinetti, N., & Falzone, C. (2021). Clinical, magnetic resonance imaging and histologic findings of canine thoracolumbar discal pseudocyst: 8 cases (2014-2019). The Journal of Small Animal Practice, 62(1), 28-32. https://doi.org/10.1111/jsap.13235
Fiorentino E, Gasparinetti N, Falzone C. Clinical, Magnetic Resonance Imaging and Histologic Findings of Canine Thoracolumbar Discal Pseudocyst: 8 Cases (2014-2019). J Small Anim Pract. 2021;62(1):28-32. PubMed PMID: 33058203.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clinical, magnetic resonance imaging and histologic findings of canine thoracolumbar discal pseudocyst: 8 cases (2014-2019). AU - Fiorentino,E, AU - Gasparinetti,N, AU - Falzone,C, Y1 - 2020/10/15/ PY - 2019/05/22/received PY - 2020/07/15/revised PY - 2020/08/30/accepted PY - 2020/10/16/pubmed PY - 2021/2/2/medline PY - 2020/10/15/entrez SP - 28 EP - 32 JF - The Journal of small animal practice JO - J Small Anim Pract VL - 62 IS - 1 N2 - OBJECTIVE: To report the clinical and MRI features, and histologic findings of thoracolumbar discal pseudocyst in dogs. MATERIALS AND METHODS: The records of eight dogs with thoracolumbar discal cyst-like structures were retrospectively collected to record their clinical signs, MRI features and surgical and histologic findings. RESULTS: Eight dogs with surgically and histologically confirmed thoracolumbar discal pseudocysts were included in the case series. Six dogs presented with acute onset and two dogs presented with subacute onset of thoracolumbar myelopathy. MRI showed compressive thoracolumbar myelopathy due to a round to oval-shaped epidural mass lesion communicating with the intervertebral disc, iso/hypointense on T1WI and mostly hyperintense on T2WI, associated with a variable contrast-enhancing wall, compatible with a cyst-like structure. These structures were surgically visualised and removed through a mini-hemilaminectomy or hemilaminectomy and submitted for histologic investigation. One dog also underwent cytologic examination of the cystic content. Similar to that in humans, histology revealed a cyst-like nature with a wall consisting of dense fibrous connective tissue containing clusters of chondroid cells accompanied by groups of notochordal cells and occasional erythrocytes; however, a real epithelial lining was missing and the term pseudocyst seemed more appropriate. CLINICAL SIGNIFICANCE: This report describes clinical signs, and MRI and histologic findings of discal pseudocysts in dogs with thoracolumbar myelopathy. Despite being rare, discal pseudocysts should be considered as a differential diagnosis in dogs with acute onset thoracolumbar myelopathy. SN - 1748-5827 UR - https://www.unboundmedicine.com/medline/citation/33058203/Clinical_magnetic_resonance_imaging_and_histologic_findings_of_canine_thoracolumbar_discal_pseudocyst:_8_cases__2014_2019__ L2 - https://doi.org/10.1111/jsap.13235 DB - PRIME DP - Unbound Medicine ER -