Citation
De León-Rodríguez, Saraí G., et al. "SARS-CoV-2: Previous Coronaviruses, Immune Response, and Development of Vaccines." Boletin Medico Del Hospital Infantil De Mexico, vol. 77, no. 5, 2020, pp. 252-261.
De León-Rodríguez SG, Hernández-Rico B, Olmo-Vázquez GD, et al. SARS-CoV-2: previous coronaviruses, immune response, and development of vaccines. Bol Med Hosp Infant Mex. 2020;77(5):252-261.
De León-Rodríguez, S. G., Hernández-Rico, B., Olmo-Vázquez, G. D., Cruz-Dávalos, I., & Bonifaz, L. C. (2020). SARS-CoV-2: previous coronaviruses, immune response, and development of vaccines. Boletin Medico Del Hospital Infantil De Mexico, 77(5), 252-261. https://doi.org/10.24875/BMHIM.20000191
De León-Rodríguez SG, et al. SARS-CoV-2: Previous Coronaviruses, Immune Response, and Development of Vaccines. Bol Med Hosp Infant Mex. 2020;77(5):252-261. PubMed PMID: 33064679.
TY - JOUR
T1 - SARS-CoV-2: previous coronaviruses, immune response, and development of vaccines.
AU - De León-Rodríguez,Saraí G,
AU - Hernández-Rico,Brenda,
AU - Olmo-Vázquez,Guadalupe Del,
AU - Cruz-Dávalos,Iván,
AU - Bonifaz,Laura C,
PY - 2020/10/16/entrez
PY - 2020/10/17/pubmed
PY - 2020/10/28/medline
KW - Ad5-nCoV vaccine
KW - Bacillus Calmette-Guerin
KW - Bacilo de Calmette-Guérin
KW - COVID-19 vaccine
KW - Coronavirus de Wuhan
KW - SARS-CoV-2 vaccine
KW - Vacuna Ad5-nCoV
KW - Vacuna COVID-19
KW - Vacuna SARS-CoV-2
KW - Vacuna mRNA-1273
KW - Wuhan coronavirus
KW - mRNA 1273 vaccine
SP - 252
EP - 261
JF - Boletin medico del Hospital Infantil de Mexico
JO - Bol Med Hosp Infant Mex
VL - 77
IS - 5
N2 - Since the emergence of the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in China at the end of 2019, when its characteristics were practically unknown, one aspect was evident: its high contagion rate. This high infection rate resulted in the spread of the virus in China, Europe, and, eventually, the rest of the world, including Mexico. At present, around 9 million people are infected, and around 470,000 have died worldwide. In this context, the need to generate protective immunity, and especially the generation of a vaccine that can protect the world population against infection in the shortest possible time, is a challenge that is being addressed in different countries using different strategies in multiple clinical trials. This opinion article will present the evidence of the induction of immune response in some of the viruses of the coronavirus family before COVID-19, such as SARS-CoV and MERS-CoV (Middle East respiratory syndrome coronavirus). The information collected about the induction of an immune response by SARS-CoV-2 will be presented, as well as a description of the vaccine candidates reported to date in the various ongoing clinical trials. Finally, an opinion based on the evidence presented will be issued on the potential success of developing vaccine prototypes.
SN - 1665-1146
UR - https://www.unboundmedicine.com/medline/citation/33064679/SARS_CoV_2:_previous_coronaviruses_immune_response_and_development_of_vaccines_
L2 - http://www.bmhim.com/frame_esp.php?id=176
DB - PRIME
DP - Unbound Medicine
ER -