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Case with long-standing gout showing various ultrasonographic features caused by monosodium urate monohydrate crystal deposition.
Mod Rheumatol Case Rep. 2020 01; 4(1):110-115.MR

Abstract

Gout, which is characterized by the deposition of monosodium urate monohydrate (MSU) in the synovial fluid and other tissues, is the most common form of inflammatory arthritis. Unlike the easily recognized acute and monoarticular gouty arthritis, advanced gout induces multiple finger joint disorders and may sometimes mimic rheumatoid arthritis (RA) or vice versa. The gold standard for gout diagnosis is the identification of MSU crystals via aspiration in the symptomatic joints or nodules; however, its feasibility and specificity may be inadequate. Recently, there have been important advances in imaging techniques, assisting in the non-invasive diagnosis of gout. Ultrasonography (US) has been known to have the ability to detect deposition of MSU crystals in patients with gout. Herein, we report an evocative case of long-standing gout with precisely detected specific US features indicating MSU crystal deposition and inflammation in multiple joints. Comprehensive US assessment included the bone, hyaline cartilage, soft tissue, subcutaneous nodules and tendon; we also discriminated gouty arthritis from RA.

Authors+Show Affiliations

Diagnostic Center for Sonography, Hokkaido University Hospital, Sapporo, Japan.Diagnostic Center for Sonography, Hokkaido University Hospital, Sapporo, Japan.Diagnostic Center for Sonography, Hokkaido University Hospital, Sapporo, Japan.Department of Surgical Pathology, Hokkaido University Hospital, Sapporo, Japan.Department of Surgical Pathology, Hokkaido University Hospital, Sapporo, Japan.Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.Diagnostic Center for Sonography, Hokkaido University Hospital, Sapporo, Japan.Department of Surgical Pathology, Hokkaido University Hospital, Sapporo, Japan.Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

33086974

Citation

Murayama, Michito, et al. "Case With Long-standing Gout Showing Various Ultrasonographic Features Caused By Monosodium Urate Monohydrate Crystal Deposition." Modern Rheumatology Case Reports, vol. 4, no. 1, 2020, pp. 110-115.
Murayama M, Nishida M, Kudo Y, et al. Case with long-standing gout showing various ultrasonographic features caused by monosodium urate monohydrate crystal deposition. Mod Rheumatol Case Rep. 2020;4(1):110-115.
Murayama, M., Nishida, M., Kudo, Y., Deguchi, T., Marukawa, K., Fujieda, Y., Abe, N., Kato, M., Shibuya, H., Matsuno, Y., & Atsumi, T. (2020). Case with long-standing gout showing various ultrasonographic features caused by monosodium urate monohydrate crystal deposition. Modern Rheumatology Case Reports, 4(1), 110-115. https://doi.org/10.1080/24725625.2019.1662987
Murayama M, et al. Case With Long-standing Gout Showing Various Ultrasonographic Features Caused By Monosodium Urate Monohydrate Crystal Deposition. Mod Rheumatol Case Rep. 2020;4(1):110-115. PubMed PMID: 33086974.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Case with long-standing gout showing various ultrasonographic features caused by monosodium urate monohydrate crystal deposition. AU - Murayama,Michito, AU - Nishida,Mutsumi, AU - Kudo,Yusuke, AU - Deguchi,Takahiro, AU - Marukawa,Katsuji, AU - Fujieda,Yuichiro, AU - Abe,Nobuya, AU - Kato,Masaru, AU - Shibuya,Hitoshi, AU - Matsuno,Yoshihiro, AU - Atsumi,Tatsuya, Y1 - 2019/09/16/ PY - 2020/10/22/entrez PY - 2020/10/23/pubmed PY - 2021/8/26/medline KW - Ultrasonography KW - double-contour sign KW - gout KW - monosodium urate crystals KW - tophus SP - 110 EP - 115 JF - Modern rheumatology case reports JO - Mod Rheumatol Case Rep VL - 4 IS - 1 N2 - Gout, which is characterized by the deposition of monosodium urate monohydrate (MSU) in the synovial fluid and other tissues, is the most common form of inflammatory arthritis. Unlike the easily recognized acute and monoarticular gouty arthritis, advanced gout induces multiple finger joint disorders and may sometimes mimic rheumatoid arthritis (RA) or vice versa. The gold standard for gout diagnosis is the identification of MSU crystals via aspiration in the symptomatic joints or nodules; however, its feasibility and specificity may be inadequate. Recently, there have been important advances in imaging techniques, assisting in the non-invasive diagnosis of gout. Ultrasonography (US) has been known to have the ability to detect deposition of MSU crystals in patients with gout. Herein, we report an evocative case of long-standing gout with precisely detected specific US features indicating MSU crystal deposition and inflammation in multiple joints. Comprehensive US assessment included the bone, hyaline cartilage, soft tissue, subcutaneous nodules and tendon; we also discriminated gouty arthritis from RA. SN - 2472-5625 UR - https://www.unboundmedicine.com/medline/citation/33086974/Case_with_long_standing_gout_showing_various_ultrasonographic_features_caused_by_monosodium_urate_monohydrate_crystal_deposition_ DB - PRIME DP - Unbound Medicine ER -