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Oxidative Stress in Parkinson's Disease: Potential Benefits of Antioxidant Supplementation.
Oxid Med Cell Longev. 2020; 2020:2360872.OM

Abstract

Parkinson's disease (PD) occurs in approximately 1% of the population over 65 years of age and has become increasingly more common with advances in age. The number of individuals older than 60 years has been increasing in modern societies, as well as life expectancy in developing countries; therefore, PD may pose an impact on the economic, social, and health structures of these countries. Oxidative stress is highlighted as an important factor in the genesis of PD, involving several enzymes and signaling molecules in the underlying mechanisms of the disease. This review presents updated data on the involvement of oxidative stress in the disease, as well as the use of antioxidant supplements in its therapy.

Authors+Show Affiliations

Oxidative Stress Research Laboratory, Institute of Biological Sciences, Federal University of Pará, Av. Augusto Corrêa, 01, Belém, Pará, Brazil 66075-110.Oxidative Stress Research Laboratory, Institute of Biological Sciences, Federal University of Pará, Av. Augusto Corrêa, 01, Belém, Pará, Brazil 66075-110.Oxidative Stress Research Laboratory, Institute of Biological Sciences, Federal University of Pará, Av. Augusto Corrêa, 01, Belém, Pará, Brazil 66075-110.Oxidative Stress Research Laboratory, Institute of Biological Sciences, Federal University of Pará, Av. Augusto Corrêa, 01, Belém, Pará, Brazil 66075-110.Oxidative Stress Research Laboratory, Institute of Biological Sciences, Federal University of Pará, Av. Augusto Corrêa, 01, Belém, Pará, Brazil 66075-110.Oxidative Stress Research Laboratory, Institute of Biological Sciences, Federal University of Pará, Av. Augusto Corrêa, 01, Belém, Pará, Brazil 66075-110.Institute of Health Sciences, Federal University of Pará, Av. Augusto Corrêa, 01, Belém, Pará, Brazil 66075-110.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

33101584

Citation

Percário, Sandro, et al. "Oxidative Stress in Parkinson's Disease: Potential Benefits of Antioxidant Supplementation." Oxidative Medicine and Cellular Longevity, vol. 2020, 2020, p. 2360872.
Percário S, da Silva Barbosa A, Varela ELP, et al. Oxidative Stress in Parkinson's Disease: Potential Benefits of Antioxidant Supplementation. Oxid Med Cell Longev. 2020;2020:2360872.
Percário, S., da Silva Barbosa, A., Varela, E. L. P., Gomes, A. R. Q., Ferreira, M. E. S., de Nazaré Araújo Moreira, T., & Dolabela, M. F. (2020). Oxidative Stress in Parkinson's Disease: Potential Benefits of Antioxidant Supplementation. Oxidative Medicine and Cellular Longevity, 2020, 2360872. https://doi.org/10.1155/2020/2360872
Percário S, et al. Oxidative Stress in Parkinson's Disease: Potential Benefits of Antioxidant Supplementation. Oxid Med Cell Longev. 2020;2020:2360872. PubMed PMID: 33101584.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Oxidative Stress in Parkinson's Disease: Potential Benefits of Antioxidant Supplementation. AU - Percário,Sandro, AU - da Silva Barbosa,Aline, AU - Varela,Everton Luiz Pompeu, AU - Gomes,Antônio Rafael Quadros, AU - Ferreira,Michelli Erica Souza, AU - de Nazaré Araújo Moreira,Thayana, AU - Dolabela,Maria Fani, Y1 - 2020/10/12/ PY - 2020/04/02/received PY - 2020/09/06/revised PY - 2020/09/21/accepted PY - 2020/10/26/entrez PY - 2020/10/27/pubmed PY - 2021/5/14/medline SP - 2360872 EP - 2360872 JF - Oxidative medicine and cellular longevity JO - Oxid Med Cell Longev VL - 2020 N2 - Parkinson's disease (PD) occurs in approximately 1% of the population over 65 years of age and has become increasingly more common with advances in age. The number of individuals older than 60 years has been increasing in modern societies, as well as life expectancy in developing countries; therefore, PD may pose an impact on the economic, social, and health structures of these countries. Oxidative stress is highlighted as an important factor in the genesis of PD, involving several enzymes and signaling molecules in the underlying mechanisms of the disease. This review presents updated data on the involvement of oxidative stress in the disease, as well as the use of antioxidant supplements in its therapy. SN - 1942-0994 UR - https://www.unboundmedicine.com/medline/citation/33101584/Oxidative_Stress_in_Parkinson's_Disease:_Potential_Benefits_of_Antioxidant_Supplementation_ L2 - https://doi.org/10.1155/2020/2360872 DB - PRIME DP - Unbound Medicine ER -