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Is there a role for childhood vaccination against COVID-19?
Pediatr Allergy Immunol. 2021 01; 32(1):9-16.PA

Abstract

Tremendous efforts are undertaken to quickly develop COVID-19 vaccines that protect vulnerable individuals from severe disease and thereby limit the health and socioeconomic impacts of the pandemic. Potential candidates are tested in adult populations, and questions arise of whether COVID-19 vaccination should be implemented in children. Compared to adults, the incidence and disease severity of COVID-19 are low in children, and despite their infectiveness, their role in disease propagation is limited. Therefore, COVID-19 vaccines will need to have fully demonstrated safety and efficacy in preventing not only complications but transmission to justify childhood vaccination. This work summarizes currently tested vaccine platforms and debates practical and ethical considerations for their potential use in children. It also discusses the already deleterious effect of the pandemic on routine childhood vaccine coverage, calling for action to limit the risks for a rise in vaccine-preventable diseases.

Authors+Show Affiliations

Center for Vaccinology, University Hospitals of Geneva, Geneva, Switzerland. Departments of Pathology-Immunology and Pediatrics, Faculty of Medicine, University of Geneva, Geneva, Switzerland. Emory Vaccine Center, Emory University, Atlanta, GA, USA.Center for Vaccinology, University Hospitals of Geneva, Geneva, Switzerland. Departments of Pathology-Immunology and Pediatrics, Faculty of Medicine, University of Geneva, Geneva, Switzerland.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

33113210

Citation

Eberhardt, Christiane Sigrid, and Claire-Anne Siegrist. "Is There a Role for Childhood Vaccination Against COVID-19?" Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology, vol. 32, no. 1, 2021, pp. 9-16.
Eberhardt CS, Siegrist CA. Is there a role for childhood vaccination against COVID-19? Pediatr Allergy Immunol. 2021;32(1):9-16.
Eberhardt, C. S., & Siegrist, C. A. (2021). Is there a role for childhood vaccination against COVID-19? Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology, 32(1), 9-16. https://doi.org/10.1111/pai.13401
Eberhardt CS, Siegrist CA. Is There a Role for Childhood Vaccination Against COVID-19. Pediatr Allergy Immunol. 2021;32(1):9-16. PubMed PMID: 33113210.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Is there a role for childhood vaccination against COVID-19? AU - Eberhardt,Christiane Sigrid, AU - Siegrist,Claire-Anne, Y1 - 2020/11/20/ PY - 2020/09/23/received PY - 2020/10/17/revised PY - 2020/10/20/accepted PY - 2020/10/29/pubmed PY - 2021/2/25/medline PY - 2020/10/28/entrez KW - COVID-19 KW - COVID-19 vaccines KW - childhood vaccination KW - efficacy KW - safety KW - transmission of disease SP - 9 EP - 16 JF - Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology JO - Pediatr Allergy Immunol VL - 32 IS - 1 N2 - Tremendous efforts are undertaken to quickly develop COVID-19 vaccines that protect vulnerable individuals from severe disease and thereby limit the health and socioeconomic impacts of the pandemic. Potential candidates are tested in adult populations, and questions arise of whether COVID-19 vaccination should be implemented in children. Compared to adults, the incidence and disease severity of COVID-19 are low in children, and despite their infectiveness, their role in disease propagation is limited. Therefore, COVID-19 vaccines will need to have fully demonstrated safety and efficacy in preventing not only complications but transmission to justify childhood vaccination. This work summarizes currently tested vaccine platforms and debates practical and ethical considerations for their potential use in children. It also discusses the already deleterious effect of the pandemic on routine childhood vaccine coverage, calling for action to limit the risks for a rise in vaccine-preventable diseases. SN - 1399-3038 UR - https://www.unboundmedicine.com/medline/citation/33113210/Is_there_a_role_for_childhood_vaccination_against_COVID_19 L2 - https://doi.org/10.1111/pai.13401 DB - PRIME DP - Unbound Medicine ER -