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The adverse effects of novel coronavirus on diabetic foot patients: A protocol for systematic review and meta analysis.
Medicine (Baltimore). 2020 Oct 23; 99(43):e22758.M

Abstract

BACKGROUND

Since the outbreak of novel coronavirus in 2019, the number of new coronavirus infections worldwide has been increasing, there is no effective treatment or vaccine. Novel coronavirus infection is closely related todiabetes, the mortality of diabetes with novel coronavirus pneumonia is significantly higher than that of non diabetic with novel coronavirus pneumonia, Diabetic foot is one of the common and serious complications of diabetes, however, no systematic study on novel coronavirus pneumonia adverse effects on diabetic foot has been found at home and abroad, however, this is a problem that can not be ignored.

METHODS

We will search each database from the built-in until April 2021. The English literature mainly searches Cochrane Library, PubMed, EMBASE, and Web of Science, while the Chinese literature comes from CNKI, CBM, VIP, and Wangfang database. Simultaneously we will retrieval clinical registration tests and grey literatures, and he researches related to the adverse effects of novel coronavirus on diabetic foot were collected, The 2 researchers worked independently on literature selection, data extraction, and quality assessment. The dichotomous data is represented by relative risk, and the continuous is expressed by mean difference or standard mean difference, eventually the data is synthesized using a fifixed effect model or a random effect model depending on whether or not heterogeneity exists. The primary outcome was clinical response rate, C-reactive protein and procalcitonin. Secondary outcomes are mainly including mortality, amputation rate, wound healing time and nerve conduction velocity. Finally, meta-analysis was conducted by RevMan software version 5.3.

RESULTS

The results of our research will be published in a peer-reviewed journal.

INPLASY REGISTRATION NUMBER

202080113.

Authors+Show Affiliations

Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan Province, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Meta-Analysis
Systematic Review

Language

eng

PubMed ID

33120781

Citation

Chen, Dongqiong, et al. "The Adverse Effects of Novel Coronavirus On Diabetic Foot Patients: a Protocol for Systematic Review and Meta Analysis." Medicine, vol. 99, no. 43, 2020, pp. e22758.
Chen D, Zhou H, Yang Y, et al. The adverse effects of novel coronavirus on diabetic foot patients: A protocol for systematic review and meta analysis. Medicine (Baltimore). 2020;99(43):e22758.
Chen, D., Zhou, H., Yang, Y., Zhang, Y., & Xie, C. (2020). The adverse effects of novel coronavirus on diabetic foot patients: A protocol for systematic review and meta analysis. Medicine, 99(43), e22758. https://doi.org/10.1097/MD.0000000000022758
Chen D, et al. The Adverse Effects of Novel Coronavirus On Diabetic Foot Patients: a Protocol for Systematic Review and Meta Analysis. Medicine (Baltimore). 2020 Oct 23;99(43):e22758. PubMed PMID: 33120781.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The adverse effects of novel coronavirus on diabetic foot patients: A protocol for systematic review and meta analysis. AU - Chen,Dongqiong, AU - Zhou,Hui, AU - Yang,Yan, AU - Zhang,Yuan, AU - Xie,Chunguang, PY - 2020/10/30/entrez PY - 2020/10/31/pubmed PY - 2020/11/11/medline SP - e22758 EP - e22758 JF - Medicine JO - Medicine (Baltimore) VL - 99 IS - 43 N2 - BACKGROUND: Since the outbreak of novel coronavirus in 2019, the number of new coronavirus infections worldwide has been increasing, there is no effective treatment or vaccine. Novel coronavirus infection is closely related todiabetes, the mortality of diabetes with novel coronavirus pneumonia is significantly higher than that of non diabetic with novel coronavirus pneumonia, Diabetic foot is one of the common and serious complications of diabetes, however, no systematic study on novel coronavirus pneumonia adverse effects on diabetic foot has been found at home and abroad, however, this is a problem that can not be ignored. METHODS: We will search each database from the built-in until April 2021. The English literature mainly searches Cochrane Library, PubMed, EMBASE, and Web of Science, while the Chinese literature comes from CNKI, CBM, VIP, and Wangfang database. Simultaneously we will retrieval clinical registration tests and grey literatures, and he researches related to the adverse effects of novel coronavirus on diabetic foot were collected, The 2 researchers worked independently on literature selection, data extraction, and quality assessment. The dichotomous data is represented by relative risk, and the continuous is expressed by mean difference or standard mean difference, eventually the data is synthesized using a fifixed effect model or a random effect model depending on whether or not heterogeneity exists. The primary outcome was clinical response rate, C-reactive protein and procalcitonin. Secondary outcomes are mainly including mortality, amputation rate, wound healing time and nerve conduction velocity. Finally, meta-analysis was conducted by RevMan software version 5.3. RESULTS: The results of our research will be published in a peer-reviewed journal. INPLASY REGISTRATION NUMBER: 202080113. SN - 1536-5964 UR - https://www.unboundmedicine.com/medline/citation/33120781/The_adverse_effects_of_novel_coronavirus_on_diabetic_foot_patients:_A_protocol_for_systematic_review_and_meta_analysis_ L2 - https://doi.org/10.1097/MD.0000000000022758 DB - PRIME DP - Unbound Medicine ER -