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[Current TSH-sensitive assays simplify thyroid diagnosis].
Schweiz Med Wochenschr. 1987 Oct 10; 117(41):1565-70.SM

Abstract

The methodology and clinical application of sensitive TSH assays are discussed. The new immunometric assays not only distinguish between normal and elevated, but also between normal and suppressed TSH values. Therefore, after clinical examination of the patient, serum TSH measurement by a sensitive assay may be used as a first line test whenever hypo- or hyperthyroidism is suspected. Normal TSH indicates euthyroidism and obviates the need for further thyroid function testing. In patients with elevated or suppressed TSH values, free T4 and (if TSH is suppressed and free T4 normal) free T3 are measured to discriminate between overt and subclinical hypo- or hyperthyroidism. Testing with TRH continues to be useful in some more complex cases, when the above-mentioned tests are not conclusive.

Authors+Show Affiliations

Medizinische Universitätsklinik, Endokrinologische Laboratorien, Inselspital, Bern.No affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Review

Language

ger

PubMed ID

3313695

Citation

Gerber, H, et al. "[Current TSH-sensitive Assays Simplify Thyroid Diagnosis]." Schweizerische Medizinische Wochenschrift, vol. 117, no. 41, 1987, pp. 1565-70.
Gerber H, Peter HJ, Koechli HP. [Current TSH-sensitive assays simplify thyroid diagnosis]. Schweiz Med Wochenschr. 1987;117(41):1565-70.
Gerber, H., Peter, H. J., & Koechli, H. P. (1987). [Current TSH-sensitive assays simplify thyroid diagnosis]. Schweizerische Medizinische Wochenschrift, 117(41), 1565-70.
Gerber H, Peter HJ, Koechli HP. [Current TSH-sensitive Assays Simplify Thyroid Diagnosis]. Schweiz Med Wochenschr. 1987 Oct 10;117(41):1565-70. PubMed PMID: 3313695.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Current TSH-sensitive assays simplify thyroid diagnosis]. AU - Gerber,H, AU - Peter,H J, AU - Koechli,H P, PY - 1987/10/10/pubmed PY - 1987/10/10/medline PY - 1987/10/10/entrez SP - 1565 EP - 70 JF - Schweizerische medizinische Wochenschrift JO - Schweiz Med Wochenschr VL - 117 IS - 41 N2 - The methodology and clinical application of sensitive TSH assays are discussed. The new immunometric assays not only distinguish between normal and elevated, but also between normal and suppressed TSH values. Therefore, after clinical examination of the patient, serum TSH measurement by a sensitive assay may be used as a first line test whenever hypo- or hyperthyroidism is suspected. Normal TSH indicates euthyroidism and obviates the need for further thyroid function testing. In patients with elevated or suppressed TSH values, free T4 and (if TSH is suppressed and free T4 normal) free T3 are measured to discriminate between overt and subclinical hypo- or hyperthyroidism. Testing with TRH continues to be useful in some more complex cases, when the above-mentioned tests are not conclusive. SN - 0036-7672 UR - https://www.unboundmedicine.com/medline/citation/3313695/[Current_TSH_sensitive_assays_simplify_thyroid_diagnosis]_ L2 - https://medlineplus.gov/thyroiddiseases.html DB - PRIME DP - Unbound Medicine ER -